Épilepsie dans le contexte neuropédiatrique sénégalais

Sarr, M.; Mapoure, Yacouba Njankouo; Sène-Diouf, F; Touré, Kamadore; Sow, Adjaratou Dieynabou; Sène, Matar; Thiam, Amath; Diagne, M.; Guéye, Lamine; Diop, Amadou Gallo; Ndiaye, Moustapha; Ip, Ndiaye

doi:10.1016/j.neurol.2007.06.002

Cited by 6 publications

(7 citation statements)

References 2 publications

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“…Epilepsy is a recognized neurological sequelae of the CM [16, 17], reported by many analytical hospital studies in children and adolescents, in SSA [18-21]. Our series and that of Ndiaye et al in Senegal [8], by identifying the sequelae of CM in 2.6% and about 1% of the causes of non-genetic epilepsy of the child and adolescent, confirmed this observation. In some series, as in ours, the history of cranial and encephalic trauma was the third most important cause of the child's non-genetic epilepsy [8, 10, 12].…”

Section: Discussionsupporting

confidence: 88%

“…[15] found 18% of post bacterial meningitis epilepsy in children previously hospitalized in Yaoundé (Cameroon). In our series, the sequelae of acute meningoencephalitis constituted 11.3% of the causes of non-genetic epilepsy of the child and adolescent, and respectively 4.5% and 9.6% of the causal factors in the series of Ndiaye et al [8] and Nguefack et al [9]. This could be explained by the persistence of epidemics of meningococcal meningitis, especially in the meningitis belt of La Peyronie, which is particularly serious in children, due to their strong lethality or the high rate of brain damage potentially epileptogenic in survivors.…”

Section: Discussionmentioning

confidence: 64%

“…The proportions of the different causal factors vary according to whether or not genetic epilepsies are included in the study population, depending on whether or not the neuroradiological and biological criteria are used, in addition to the clinical and EEG criteria [1, 4]. According to the series combining clinical and cerebral CT criteria, such as ours, the etiology of non-genetic epilepsy of the child was dominated by abnormalities of pregnancy or antenatal factors and childbirth or perinatal factors and CNS infections [4, 8-11] In two african literature reviews, one in 2006 [1] and the other in 2014, in SSA [7], an implication of perinatal causes was found respectively between 1-36% and between 2%-65% of cases of epilepsy and therefore considered to be major. In our series, the sequelae of perinatal cerebral damage were the leading cause of non-genetic epilepsy of the child and adolescent, or 34.8%, after the undetermined causes, thus confirming the literature data.…”

Section: Discussionmentioning

confidence: 99%

“…Infectious pathology is the other major provider of potentially epileptogenic brain lesions, estimated to be between 1.6 and 6.3% of cases of epilepsy especially in children, in African and Asian work [13]. The history of CNS infection was 20.2% and 11.9% of the causal factors of non-genetic epilepsy in Dakar, respectively in children [8] and in children and adolescents [4] and up to 29.3% of the causative factors of focal genetic and non-genetic focal epilepsies of the child in Cameroon, including non-specific febrile seizures [9]. The sequelae of CNS infections accounted for 14.8% of the causes of non-genetic epilepsy of the child and adolescent in our series.…”

Section: Discussionmentioning

confidence: 99%

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Etiologies of non-genetic epilepsies of child and adolescent, newly diagnosed in Ouagadougou, Burkina Faso

Lompo¹,

Ousseini²,

Dao³

et al. 2018

Pan Afr Med J

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Introduction in sub-Saharan Africa, epilepsy is common and mainly concerns children before the age of 15 years. The data on childhood epilepsy is parcel, but a high prevalence of non-genetic epilepsy is frequently reported. EEG, TDM and MRI devices are rare. The aim of this work was to study the etiological aspects of non - genetic epilepsy of the child and adolescent, newly diagnosed in Ouagadougou, Burkina Faso. Methods This was a cross-sectional, descriptive, multicentric study, from 01/01/2016 to 31/12/2016, involving patients aged 0 to 18 years old, epileptic, newly diagnosed, in the city of Ouagadougou. Each patient included in the study was to have had an EEG and brain CT scan and/or brain MRI and to gather the anamnestic and electro clinical arguments for non-genetic epilepsy. Sociodemographic, clinical, EEG and neuroradiological data were analyzed. An univariate analysis was used to determine the electro-clinical and neuro-radiological characteristics associated with epilepsies of structural causes. Results In all 115 patients were collected, with an average age of onset of epilepsy of 8.2 years, a male predominance with a sex ratio to 1.67. Risk factors of epilepsy was present in 74.8%; They were dominated by perinatal events in 79.1%. Focal seizures, daily frequency of these seizures and focal epilepsy, were predominant, respectively in 53%, 58% and 60.9% of cases. Brain scan and Brain MRI where performed in 90.4% and 9.6% of patients, respectively. The brain sequelaes of perinatal adverse events, the sequelae of central nervous system infections, and the sequelae of cranial and brain trauma, with 34.8%, 14.8%, and 5.2% respectively, were the main causes of non- genetic epilepsies of the child and adolescent. No cause was identified in 37.4% of cases. Conclusion The improvement of policies in the field of maternal and child health and the generalization of the control of infectious and parasitic diseases, including malaria, may contribute to the reduction of non-genetic epilepsy in sub-Saharan Africa.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Etiologies of non-genetic epilepsies of child and adolescent, newly diagnosed in Ouagadougou, Burkina Faso

Lompo¹,

Ousseini²,

Dao³

et al. 2018

Pan Afr Med J

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“…In our study there is an unexplained discrepancy between the high prevalence of epilepsy and the absence of inbreeding. Indeed most African authors have shown the high risk of epilepsy with the existence of consanguinity between parents [7].…”

Section: Epidemiological Datamentioning

confidence: 99%

Assessment of State of Convulsive Child in Hospital National Children Albert Royer, Dakar

Thiam¹,

Moustapha²,

Sandrine³

et al. 2017

Clin Pediatr OA

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Introduction: The state of epilepticus in children is considered as a medical emergency which involves the vital and functional prognosis of the patient. The difficulties of this support in our country are linked to the lack of pediatric intensive care unit. The aim of our study is to evaluate the clinical, therapeutic, scalable and etiological states of epilepticus in children at Hospital Albert Royer National Children, Dakar.Methods: This is a prospective study which includes all patients aged between 2 months and 16 years who were hospitalized between 1 August, 2014 and 31 May, 2015 for a prolonged convulsion over 5 minutes and/or with at least 3 episodes of successive convulsions. We have not included the newborns and non-convulsive state epilepticus patients. The treatment protocol consists of the use of diazepam as first line, after 60 minutes if the crisis persists; diazepam phenobarbital was associated with the second line. Results:We collected 53 cases of state epilepticus (29 boys and 24 girls), which turned out to be a hospital incidence of 4.2%. The mean age was 48.5 months. Three quarters of our patients (n=40) were received emergency beyond 30 minutes after the onset of convulsions where the generalized seizures (n=42) were more common than partial seizures (n=11). The convulsions occurred in a context of fever in 38 patients. The metabolic balance was in favor of hyponatremia in 13 cases. Twenty-four patients (45.3%) have received only phenobarbital diazepam combination within 60 minutes after the onset of seizures. Conclusions:The state epilepticus cases are frequent in the hospital emergency department especially for infants from 2 months to 3 years. It was observed that the patients unfortunately received emergency in late beyond 30 minutes after the onset of convulsions.

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