Epigenetic processes associated with neonatal spinal transection
Nicholas J. Collins,
Taylor S. Campbell,
Aimee L. Bozeman
et al.
Abstract:In early development, the spinal cord in healthy or disease states displays remarkable activity‐dependent changes in plasticity, which may be in part due to the increased activity of brain derived neurotrophic factor (BDNF). Indeed, BDNF delivery has been efficacious in partially ameliorating many of the neurobiological and behavioral consequences of spinal cord injury (SCI), making elucidating the role of BDNF in the normative developing and injured spinal cord a critical research focus. Recent work in our la… Show more
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