Epigenetic clocks and gliomas: unveiling the molecular interactions between aging and tumor development
Shiliang Chen,
Yi Jiang,
Cong Wang
et al.
Abstract:Gliomas, the most prevalent and aggressive primary brain tumors, represent a diverse group of malignancies originating from glial cells. These tumors account for significant brain tumor-related morbidity and mortality, with higher incidence rates in North America and Europe compared to Asia and Africa. Genetic predispositions and environmental factors, particularly ionizing radiation, critically impact glioma risk. Epigenetics, particularly DNA methylation, plays a pivotal role in glioma research, with IDH-mut… Show more
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