Epidural ropivacaine 1% with and without sufentanil addition for Caesarean section

Bachmann-Mennenga, B.; Veit, Gunter; Biscoping, J.; Steinicke, B

doi:10.1111/j.1399-6576.2004.00580.x

Cited by 7 publications

(6 citation statements)

References 32 publications

(41 reference statements)

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“…Degree and onset of the motor block as well as neonatal outcome were unaffected by sufentanil addition. This result is in contrast to a previous study by our group (13) which could not detect a significant effect of sufentanil addition to ropivacaine 1%. Perhaps, these finding could be explained by the fact that we had used a 1% solution, which may have masked the influence of sufentanil.…”

Section: Discussioncontrasting

confidence: 99%

“…To our knowledge no similar study has been performed to date. In a previous study with ropivacaine 1% we were unable to find an effect on the onset time of the sensory block or the analgesic quality by the addition of 10 or 20 µg of sufentanil (13).…”

mentioning

confidence: 78%

“…The methods have been described in detail previously (13). In brief, this study was approved by the ethics committee of the University of Muenster, Germany.…”

Section: Methodsmentioning

confidence: 99%

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Efficacy of sufentanil addition to ropivacaine epidural anaesthesia for Caesarean section

Bachmann-Mennenga

Veit

Steinicke

et al. 2005

Acta Anaesthesiol Scand

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Section: Discussioncontrasting

confidence: 99%

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confidence: 78%

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Efficacy of sufentanil addition to ropivacaine epidural anaesthesia for Caesarean section

Bachmann-Mennenga

Veit

Steinicke

et al. 2005

Acta Anaesthesiol Scand

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“…Sufentanil can be used for sedation with a low dose (2.5–5.0 µg) providing adequate analgesia for surgery. 2 , 3 …”

Section: Introductionmentioning

confidence: 99%

Addition of low-dose sufentanil to ropivacaine for reducing shivering and visceral traction pain during cesarean section

et al. 2021

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Objective To investigate the efficacy of low-dose sufentanil for preventing shivering and visceral traction pain during cesarean section under spinal anesthesia. Methods This was a prospective, randomized, controlled study. A total of 112 full-term parturients who underwent elective caesarean delivery were randomly divided into two groups. Group R received 0.75% isobaric ropivacaine intrathecally and group RS received 0.75% isobaric ropivacaine plus 5 µg sufentanil intrathecally. Results There were no significant differences in the maximum sensory block time, motor block time, duration of the surgery, and heart rate, mean arterial pressure, and blood oxygen saturation before and 1, 5, and 10 minutes after spinal anesthesia, and at the end of the surgery between the two groups. Shivering was significantly more common in group R (n = 30) than in group RS (n = 8). The incidence of visceral traction pain in group R (46.43%) was significantly higher than that in group RS (14.29%). There was no significant difference in the newborns’ Apgar scores between the groups. Conclusion Adding low-dose sufentanil to ropivacaine can significantly reduce the incidence of shivering and visceral traction pain after spinal anesthesia.

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“…Sufentanil, a lipophilic opioid, spinal administration in conjunction with a local anesthetics is widely used for pain relief in cesarean section because of the properties of its dose minimizing and adverse effects reduction. [ 4 , 5 ] It should be clearly stressed that the central blocks effect of sufentanil in cesarean section and the side effects on the condition of a foetus or its recorded concentration in the umbilical blood were not in parallel. [ 6 , 7 ] Therefore, we are reasonably sure that the ideal method of providing relief from somato-visceral pain is to use a combination of drugs that epidural administration of local anesthetics in combination with sufentanil for cesarean section in parturients with scarred uterus.…”

Section: Introductionmentioning

confidence: 99%

The dose response of sufentanil as an adjuvant to ropivacaine in cesarean section for relief from somato-visceral pain under epidural anesthesia in parturients with scarred uterus

Lü

Dong²,

Yu³

et al. 2018

Medicine

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Visceral pain is common during epidural anesthesia with mini dose local anesthetics in parturients during cesarean section. To reduce or avoid this complication caused by traction on the abdominal viscera, this study aimed to determine the 50% effective dose (ED50) and 95% effective dose (ED95) of epidural sufentanil as an adjuvant combination with local anesthetics for relief visceral pain in parturients with scarred uterus undergoing elective cesarean section.One hundred parturients with scarred uterus undergoing elective cesarean section under epidural anesthesia were enrolled in this randomized, double-blinded, dose-ranging study. Parturients received 5, 10, 15, 20, and 25 μg epidural sufentanil as an adjuvant with 10 mL of 0.65% ropivacaine. Successful epidural anesthesia was defined as a sixth thoracic vertebra (T6) sensory level achieved within 20 minutes after epidural drugs administration and/or no visceral pain by traction on the abdominal viscera during the cesarean section. The ED50 and ED95 were calculated with a logistic regression model.ED50 and ED95 of epidural sufentanil for successful of the pain-free from visceral pain were 10.7 μg [95% confidence interval (CI): 2.4–14.4 μg) and 28.1 μg (95% CI: 19.4–44.0 μg), respectively. The onset time to sensory block, maximum Bromage scale and duration of motor block were significant different with dose of sufentanil >20 μg (P < .05, compared with the other dose groups). With the dose of epidural sufentanil >20 μg could result in an increase of incidence of maternals’ adverse effects. Compared with a different dose of sufentanil, epidural administed sufentanil between 15 μg and 20 μg can maximize parturients’ satisfaction.Our study showed that sufentanil could be used in combination with ropivacaine for relief from somato-visceral pain in patients with scarred uterus during elective cesarean section during epidural anesthesia, and that maximized parturients’ satisfaction could be achieved when the use of sufentanil with the dose between 15 μg and 20 μg for epidural anesthesia.

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Epidural ropivacaine 1% with and without sufentanil addition for Caesarean section

Abstract: Ropivacaine 1% alone provided sufficient analgesia. Sufentanil addition did not significantly improve the quality of epidural anaesthesia with ropivacaine 1.0% for Caesarean section.

Cited by 7 publications

References 32 publications

Efficacy of sufentanil addition to ropivacaine epidural anaesthesia for Caesarean section

Efficacy of sufentanil addition to ropivacaine epidural anaesthesia for Caesarean section

Addition of low-dose sufentanil to ropivacaine for reducing shivering and visceral traction pain during cesarean section

The dose response of sufentanil as an adjuvant to ropivacaine in cesarean section for relief from somato-visceral pain under epidural anesthesia in parturients with scarred uterus

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