Epidermolysis Bullosa Acquisita of MRSA Skin Carrier: A Case of Successful Total Hip Arthroplasty

Homma, Yasuhiro; Baba, Tomonori; Goto, Kenji; Maruyama, Yoshihiro

doi:10.5301/hipint.5000243

Cited by 2 publications

(3 citation statements)

References 13 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Few cases of successful primary THA in methicillin-resistant Staphylococcus aureus (MRSA) carrier patients, who are at higher risk of infection, were documented in the literature which encouraged our decision to proceed [9].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Epidermolysis Bullosa: A Case of Successful Total Hip Arthroplasty

Kawasmi

Ajlouni

Almanaseer

et al. 2020

Cureus

View full text Add to dashboard Cite

Epidermolysis bullosa (EB) is a rare dermatological disease in which patients suffer from skin fragility and blisters. One of the major complications is the development of skin infections, which may preclude surgical intervention. We present a case of a 49-year-old female with a past medical history of EB, who presented to the emergency department (ED) with right groin pain of one-hour duration after falling on her right side. The patient underwent a successful open reduction and internal fixation for her right hip without complications. Over the course of three months after the procedure, she experienced worsening of the pain accompanied by skin necrosis and total collapse of the femoral head. Subsequent total hip replacement surgery was performed using a cementless (Zimmer, Warsaw, IN) prosthesis and fixated via cannulated screws. To decrease the risk of infection, IV cefazolin was given as a prophylactic antibiotic preoperatively. Vancomycin IV and imipenem/cilastatin IV were given for four days postoperatively. We made sure that our patient is experiencing the least possible pain by giving sufficient analgesics after the surgery. We used morphine, paracetamol, and gabapentin for pain control. For 25 days after the surgery, the patient did not complain of any pain. Upon follow-up, sutures were removed, and no surgical wound infection, rashes, or lacerations were noted. We encourage orthopedic surgeons dealing with patients suffering from dermatological conditions with fragile skin such as EB and decreased level of activity that requires total hip arthroplasty to proceed with the surgical intervention after considering adequate infection control to improve quality of life.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Pressure sites are more exposed using the lateral or posterior approaches. Consequently, the anterior approach was chosen to avoid the associated complications, predominantly pressure ulcers [9].…”

Section: Discussionmentioning

confidence: 99%

Epidermolysis Bullosa: A Case of Successful Total Hip Arthroplasty

Kawasmi

Ajlouni

Almanaseer

et al. 2020

Cureus

View full text Add to dashboard Cite

show abstract

“…Explanation : There are few case series and cases studies reporting the use of steroid pulse therapy during the treatment of EBA, and they provide no conclusions with regard to efficacy.…”

Section: Eba‐cq4: Is Steroid Pulse Therapy Useful?mentioning

confidence: 99%

Japanese guidelines for the management of pemphigoid (including epidermolysis bullosa acquisita)

Ujiie

Iwata

Yamagami

et al. 2019

The Journal of Dermatology

View full text Add to dashboard Cite

The pemphigoid group is a category of autoimmune subepidermal blistering diseases in which autoantibodies deposit linearly at the epidermal basement membrane zone (BMZ). The main subtypes of pemphigoid mediated by immunoglobulin G autoantibodies are bullous pemphigoid (BP), mucous membrane pemphigoid (MMP) and epidermolysis bullosa acquisita (EBA). To establish the first guidelines approved by the Japanese Dermatological Association for the management of pemphigoid diseases, the Committee for Guidelines for the Management of Pemphigoid Diseases (Including EBA) was founded as part of the Study Group for Rare Intractable Skin Diseases under the Ministry of Health, Labor and Welfare Research Project on Overcoming Intractable Diseases. These guidelines aim to provide current information for the management of BP, MMP and EBA in Japan. Based on evidence, the guidelines summarize the clinical and immunological manifestations, pathophysiologies, diagnostic criteria, disease severity determination criteria, treatment algorithms and treatment recommendations. Because of the rarity of these diseases, there are few clinical studies with a high degree of evidence, so several parts of these guidelines were established based on the opinions of the Committee. To further optimize these guidelines, periodic revision in line with the new evidence is necessary.

show abstract

Epidermolysis Bullosa Acquisita of MRSA Skin Carrier: A Case of Successful Total Hip Arthroplasty

Abstract: Although care must be taken by medical professionals to avoid the prescription of unnecessary antibiotics, when used appropriately, there appears to be substantial benefits to be gained in the field of joint replacement for patients who are at high risk of infection.

Cited by 2 publications

References 13 publications

Epidermolysis Bullosa: A Case of Successful Total Hip Arthroplasty

Epidermolysis Bullosa: A Case of Successful Total Hip Arthroplasty

Japanese guidelines for the management of pemphigoid (including epidermolysis bullosa acquisita)

Contact Info

Product

Resources

About