Epidermolysis bullosa acquisita: A comprehensive review

“…Such aAbs against COL7 are detectable in the basement membrane and in the serum. Despite advancements in the understanding of the pathogenesis, effective treatment still remains a challenge (35). Experimental models of EBA support the idea that binding of aAbs to COL7 mediates inflammation and triggers blister formation (18,36).…”

Section: Discussionmentioning

confidence: 99%

Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita

et al. 2020

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“…EBA is a rare autoimmune blistering disease that has autoantibodies to collagen VII. 55 Vesicle and bullae formation appear predominantly at sites of trauma. Mucosal involvement occurs in 23% of EBA patients, and the most affected localizations are the oral, ocular, and genital areas.…”

Section: Vesiculobullous Disordersmentioning

confidence: 99%

“…Mucosal involvement occurs in 23% of EBA patients, and the most affected localizations are the oral, ocular, and genital areas. 55 LABD is characterized by tense vesicles and bullae that usually appear 1-15 days after drug exposure. 1 IgA autoantibodies produced against basement membrane antigens are responsible for this entity.…”

Section: Vesiculobullous Disordersmentioning

confidence: 99%

Approach to the aphthous lesions of the oral mucosa

Arıca

Ferhatosmanoğlu

2021

Mucosa

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Aphthous oral cavity lesions are common in clinical practice that negatively affect the quality of life. It is possible to reveal the etiological cause in aphthous lesions, with detailed history, physical examination findings, and appropriate laboratory evaluation. In this article, we aimed to review the differential diagnosis by examining the conditions that need to be questioned with clinical clues to reveal the correct etiological cause in a patient presenting with the complaint of oral aphthae.

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“…Epidermolysis bullosa (EB) is a dermatological condition, inherited or rarely acquired [1], characterized by increased tendency to develop blisters (bullae) either spontaneously [2], or after mechanical trauma. Inherited EB is four types, defined by the levels in the skin at which blistering occurs (Table 1) [[2], [3], [4]].…”

Section: Introductionmentioning

confidence: 99%

Management of epidermolysis bullosa simplex in pregnancy: A case report

Shah

Kumaraswami

Mushi

2019

Case Reports in Women's Health

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Epidermolysis bullosa (EB) encompasses a group of diseases characterized by extreme fragility of skin and mucous membranes, resulting in blister formation following minimal injury. There are 4 types of EB, with epidermolysis bullosa simplex (EBS) being the most common. We report our experience with the care of a parturient woman diagnosed with EBS. There is little literature on pregnancy in women with this condition. Special precautions are necessary during diagnostic and therapeutic interventions to avoid bullae formation or exacerbation of existing lesions. Frictional or shearing forces are typically more damaging than compressive forces. Multidisciplinary planning was done for our patient to ensure uneventful labor and delivery. Elective induction of labor was started at 40 weeks of gestation. She eventually underwent a cesarean delivery after failed trial of labor. We present this case to highlight the obstetric and anesthetic implications of caring for a parturient with EBS.

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Epidermolysis bullosa acquisita: A comprehensive review

Cited by 57 publications

References 133 publications

Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita

Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita

Approach to the aphthous lesions of the oral mucosa

Management of epidermolysis bullosa simplex in pregnancy: A case report

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