Epidermoid Cysts of the Testis: A Clinical and Pathologic Analysis of 69 Cases from the Testicular Tumor Registry

Price, Edward B.

doi:10.1016/s0022-5347(17)62236-5

Cited by 212 publications

(135 citation statements)

References 4 publications

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“…Epidermoid cysts ( Figure 6) constitute approximately 1-2% of all resected testicular lesions [8]. Epidermoid cysts are composed of a variable quantity of keratinising, stratified epithelium, and in some a well-defined fibrous wall.…”

Section: Tumour-like Pathologies Epidermoid Cystsmentioning

confidence: 99%

Focal testicular lesions: colour Doppler ultrasound, contrast-enhanced ultrasound and tissue elastography as adjuvants to the diagnosis

Huang¹,

Sidhu²

2012

The British Journal of Radiology

121

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ABSTRACT. The aim of this review is to illustrate the potential of different and newer ultrasound techniques beyond conventional B-mode imaging, including colour Doppler ultrasound, contrast-enhanced ultrasound (CEUS) and tissue elastography, in the characterisation of both benign and malignant intratesticular lesions. Normally, testicular malignancies, either primary or secondary, demonstrate an increase in colour Doppler signal. However, there is a diversity of benign testicular lesions that may mimic testicular malignancies. The use of CEUS improves characterisation of testicular lesions, and confirms lack of vascularity in benign abnormalities such as epidermoid cysts, infarctions, abscesses and changes following trauma. Tissue elastography allows further evaluation of the cellular consistency of the abnormality. Familiarity with the appearances seen with these ultrasound techniques in both benign and malignant abnormalities should aid in improving confidence in arriving at the correct diagnosis.

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Section: Tumour-like Pathologies Epidermoid Cystsmentioning

confidence: 99%

Focal testicular lesions: colour Doppler ultrasound, contrast-enhanced ultrasound and tissue elastography as adjuvants to the diagnosis

Huang¹,

Sidhu²

2012

The British Journal of Radiology

121

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“…Epidermoid cyst of the testis is an uncommon benign lesion accounting for <1% of all testicular tumors (1). Several authors have hypothesized that it originates from squamous metaplasia of the mesothelium, rete testis epithelium, or seminiferous tubular cells; others believe that it represents a monodermal teratoma (1,2).…”

mentioning

confidence: 99%

“…Several authors have hypothesized that it originates from squamous metaplasia of the mesothelium, rete testis epithelium, or seminiferous tubular cells; others believe that it represents a monodermal teratoma (1,2). The main differential diagnostic consideration of epidermoid cyst is teratoma of the testis.…”

mentioning

confidence: 99%

Interphase Fluorescence In situ Hybridization Analysis of Chromosome 12p Abnormalities Is Useful for Distinguishing Epidermoid Cysts of the Testis from Pure Mature Teratoma

Liu

Zhang²,

MacLennan

et al. 2006

Clinical Cancer Research

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Purpose: The distinction of epidermoid cyst of the testis from teratoma is of critical importance because the former is benign and the latter is a malignant tumor that may have associated metastasis of either teratomatous or non^teratomatous germ cell tumor types. Chromosome 12p abnormalities are seen in the vast majority of testicular germ cell tumors of adults and are present in all histologic subtypes. In this study, we investigated the clinical utility of interphase fluorescence in situ hybridization (FISH) analysis of chromosome 12p abnormalities for distinguishing epidermoid cysts of the testis from pure mature teratoma. Experimental Design: Sixteen testicular epidermoid cysts and 17 testicular teratomas were investigated for isochromosome 12p [i(12p)] and 12p overrepresentation using interphase FISH analysis. Results: Neither i(12p) nor 12p overrepresentation were observed in 16 epidermoid cyst cases, whereas i(12p) was detected in 76% of teratomas and 12p overrepresentation was identified in 29% of teratomas. Overall, 88% of testicular teratomas had chromosome 12p abnormalities. Conclusions: FISH identification of i(12p) and/or 12p overrepresentation in routinely processed surgical specimens is a useful ancillary diagnostic tool in distinguishing testicular epidermoid cysts from teratoma.

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“…These tumours can occur at any age, but they are most common during the second to fourth decades [1,2]. Epidermoid cysts can be multiple, bilateral or both [3].…”

Section: Discussionmentioning

confidence: 99%

Intrascrotal extratesticular epidermoid cyst

Agarwal¹,

Agarwal²

2011

BJR

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ABSTRACT. Epidermoid cysts are rare tumours, which account for 1% of all testicular tumours. Very rarely, they are intrascrotal but extratesticular. We present a rare case of an intrascrotal extratesticular cyst. The triad of findings were sonographic appearance of an onion ring, avascularity on Doppler sonography and negative results of tumour markers; these are highly suggestive of an epidermoid cyst.

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Epidermoid Cysts of the Testis: A Clinical and Pathologic Analysis of 69 Cases from the Testicular Tumor Registry

Cited by 212 publications

References 4 publications

Focal testicular lesions: colour Doppler ultrasound, contrast-enhanced ultrasound and tissue elastography as adjuvants to the diagnosis

Focal testicular lesions: colour Doppler ultrasound, contrast-enhanced ultrasound and tissue elastography as adjuvants to the diagnosis

Interphase Fluorescence In situ Hybridization Analysis of Chromosome 12p Abnormalities Is Useful for Distinguishing Epidermoid Cysts of the Testis from Pure Mature Teratoma

Intrascrotal extratesticular epidermoid cyst

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