Epidermoid carcinoma of the mouth and pharynx at memorial sloan-kettering cancer center, 1965 to 1969

Farr, Hollon W.; Goldfarb, Paul M.; Farr, C

doi:10.1016/0002-9610(80)90213-5

Cited by 41 publications

(10 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These patterns have been delineated through careful anatomic studies of the lymphatic drainage for different sites of the head and neck [6][7][8] and also through clinical studies of this distribution. [9][10][11][12][13][14][15][16] Many reports [17][18][19][20][21][22][23][24][25] have also shown the effectiveness of less radical procedures such as SOHND and LND as elective or therapeutic procedures compared with radical neck dissection considering the regional recurrence. [26][27][28] To date however, there is a lack of assurance about the impact on survival for this type of neck dissection in the setting of a prospective and randomized clinical study.…”

Section: Commentsmentioning

confidence: 99%

Neck lymph node metastases to the posterior triangle apex: Evaluation of clinical and histopathological risk factors

Chone¹,

Crespo²,

Rezende³

et al. 2000

Head Neck

View full text Add to dashboard Cite

Background Dissection of posterior triangle apex (APEX) is a surgical step in supraomohyoid and lateral neck dissections. The prevalence of lymphatic metastases at this site and the clinicohistopathologic conditions that influence their occurrence have not been established. We have evaluated the prevalence and the risk factors for cervical metastases in lymph nodes of the APEX. Methods Sixty‐two neck dissections were performed in 51 patients with squamous cell carcinoma of the oropharynx, hypopharynx, oral cavity, glottic larynx, and supraglottic larynx or with primary occult tumor. We correlated the presence of positive metastases in the APEX with the neck level involved either clinically (CLIN) or histopathologically (H/P) and with the number of CLIN‐ or H/P‐positive neck levels with metastases. The prevalence of metastases in the APEX in elective (N0) and therapeutic (N+) neck dissections was also compared. This prevalence was also compared with that for each neck level. The histopathologic comparisons between the APEX and the neck levels were calculated for N0, N+, and all neck dissections. The primary site of tumor was correlated with the presence of H/P‐positive nodes in the APEX. Results The overall prevalence of lymphatic metastases in the APEX was 6.5%. The prevalence in N0 neck dissections was 2.3% and in N+ neck dissections it was 16.7%. The prevalence of lymphatic metastases in the APEX for primary tumors of pharynx was 23.1%, for the oral cavity it was 3.6%, and it was 0% for other sites. Metastases in the APEX were not influenced by the neck level with CLIN or H/P metastases in N+ necks. The number of CLIN‐ or H/P‐positive neck levels had no influence on histopathologic metastases in the APEX. Factors that influenced metastases in the APEX were positive histopathologic metastases at level II for N0 neck dissections and positive histopathologic metastases at level II or III for all neck dissections. All the comparisons were analyzed using Fisher's or Poisson's test. Conclusions The prevalence of histopathologic metastases in the APEX in N+ necks is 7.3 times greater than that of N0 necks and for primary tumors of pharynx it was 6.4 times greater than for the oral cavity and significantly greater than for the larynx. Histopathologic metastases at level II for clinically N0 necks and histopathologic metastases to level II or III for all neck dissections are risk factors for metastases in the APEX. The number of positive levels did not influence the prevalence of metastases in the APEX. There are no isolated metastases in the APEX of the posterior triangle. © 2000 John Wiley & Sons, Inc. Head Neck 22: 564–571, 2000.

show abstract

Section: Commentsmentioning

confidence: 99%

Neck lymph node metastases to the posterior triangle apex: Evaluation of clinical and histopathological risk factors

Chone¹,

Crespo²,

Rezende³

et al. 2000

Head Neck

View full text Add to dashboard Cite

show abstract

“…Regardless of the site of the primary tumor, the presence of a single metastatic lymph node in either the ipsilateral or contralateral side of the neck reduces the 5-year survival rate by about 50%. The presence of a single metastatic lymph node in each side of the neck reduces the survival rate to nearly 25% of that expected in patients without any cervical nodal metastasis [2][3][4][5].…”

Section: Radiologistsmentioning

confidence: 99%

“…Thus, for most primary tumor sites in the head and neck, the presence of one metastatic lymph node in both sides of the neck with tumor extending beyond the nodal capsule in at least one node reduces survival to one eighth of that of a patient with the same primary tumor, but without any nodal metastases [2][3][4][5]. The striking effect that lymph node metastases have on prognosis and the efficacy of CT and MR imaging to detect such disease have combined to make evaluation of nodal metastases a fundamental part of the preoperative evaluation and follow-up of patients with tumors in the head and neck.…”

Section: Radiologistsmentioning

confidence: 99%

Detection of metastasis in cervical lymph nodes: CT and MR criteria and differential diagnosis.

Som

1992

American Journal of Roentgenology

426

276

View full text Add to dashboard Cite

“…Five year survival is reduced by 50 % when a single metastatic cervical lymph node is present, and drops to 25 % in the setting of a contralateral metastatic cervical lymph node [1,2]. In addition, nodal metastatic disease not only increases the risk of local recurrence but also increases the risk of distant metastases [3,4].…”

Section: Introductionmentioning

confidence: 99%

Lymph Node Disease and Advanced Head and Neck Imaging: A Review of the 2013 Literature

Khan

2014

Curr Radiol Rep

View full text Add to dashboard Cite

Detection and differentiation of lymph node disease in the head and neck can be very difficult but is of importance for staging and treating head and neck (H&N) tumors. This topic is therefore a source of much ongoing study. With constantly evolving imaging technology, there is an ongoing need for evaluation of both new and improved techniques, and potential new uses of current modalities. CT, MRI, and PET are examined in this article, with a focus on H&N disease processes and the technical aspects of imaging. The goal of this review article is to bring the reader up to date on pertinent articles in advanced imaging of H&N lymph node disease from the year 2013.

show abstract

Epidermoid carcinoma of the mouth and pharynx at memorial sloan-kettering cancer center, 1965 to 1969

Cited by 41 publications

References 26 publications

Neck lymph node metastases to the posterior triangle apex: Evaluation of clinical and histopathological risk factors

Neck lymph node metastases to the posterior triangle apex: Evaluation of clinical and histopathological risk factors

Detection of metastasis in cervical lymph nodes: CT and MR criteria and differential diagnosis.

Lymph Node Disease and Advanced Head and Neck Imaging: A Review of the 2013 Literature

Contact Info

Product

Resources

About