Epidermal turnover in the planarianSchmidtea mediterraneainvolves basal cell extrusion and intestinal digestion
Jun-Ru Lee,
Tobias Boothe,
Clemens Mauksch
et al.
Abstract:SummaryPlanarian flatworms undergo continuous internal turnover, wherein old cells are replaced by the division progeny of adult pluripotent stem cells known as neoblasts. How dynamic cell turnover is executed at the organismal scale remains an intriguing question in planarians and biological systems in general. While previous studies have predominantly focused on neoblast proliferation, little is known about the processes that mediate cell loss during tissue homeostasis. Here, we use the planarian epidermis a… Show more
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