Epidermal necrolysis: characterization of different phenotypes using an unsupervised clustering analysis

Novel inflammatory markers and in‐hospital mortality in epidermal necrolysis—A monocentric study of 137 patients

“…10 We also showed that the lymphocyte count was significantly lower in EN patients with a poorer prognosis. 10 Our study is limited by its retrospective and monocentric design. The overall severity of the patients was mild (median SCORTEN 2, final BSA affected 25%) but similar to other large EN series.…”

“…We could explain that NLR was not associated to prognosis in our cohort because, as we previously reported, neutropenia is frequent in severe EN patients. 10 We also showed that the lymphocyte count was significantly lower in EN patients with a poorer prognosis. 10 Our study is limited by its retrospective and monocentric design.…”

Outcomes Associated With Neutropenia and Lymphopenia in Epidermal Necrolysis

“…In a recently published study of 377 patients with EN, Wang et al 3 reported that baseline leukopenia (<4000 white blood cells/mm 3 at hospital admission) af- a Threshold used in original publication. 4…”

“…Additionally, female patients are recommended to undergo an annual mammogram beginning at ages 30 to 35 years and annual endometrial cancer ultrasonography beginning at ages 30 to 35 years. 4,5 Skin lesions associated with the syndrome are treated with surgical excision, chemical peels, and laser resurfacing. 1 Report of a Case | A 67-year-old White woman with multiple asymptomatic facial papules presented to our university clinic (University of Oklahoma; Oklahoma City) in 2018 for fullbody skin examinations.…”

“…We previously reported that the median blood lymphocyte counts were low in the patients with the most severe disease, whereas neutrophil counts, although lower in those with severe disease, remained in the normal range, suggesting that lymphocytes may be the most affected leukocytes. 4 In the present study, we aimed to investigate the association between lymphocytes and neutrophils and outcomes of the disease.…”