Epidermal inclusion cyst in the thyroid gland

Palacio, Maria Naranjo; Gonzalez-Mosquera, Luis F.; Rosenthal, David S.; Kunar, Salini; Tao, Qi; Gebre, Wondwossen; Liao, Huijuan

doi:10.21037/sci-2020-021

Cited by 3 publications

(3 citation statements)

References 5 publications

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“…On cytology, they appear as many mature superficial squamous cells with intact nuclei, anucleate squames, clusters of neutrophils and lymphocytes, macrophages, and amorphous debris in the background. It is rare for EICs to undergo malignant transformation, and no such cases have been reported in thyroid cases 9 . This is a picture that is similar to the one obtained in our case.…”

Section: Discussionmentioning

confidence: 99%

A case report of uncommon giant epidermal inclusion cyst found in the thyroid gland

Mousa,

Aljassem

2024

Annals of Medicine &Amp; Surgery

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Introduction and importance: This case report describes a rare occurrence of an epidermal inclusion cyst (EIC) being found in the thyroid gland and highlights the importance of considering uncommon entities like EIC in the differential diagnosis of thyroid lesions. Case presentation: A 68-year-old male presented with a large, painless swelling in the anterior neck, causing dysphagia and dysphonia. Imaging and cytology confirmed a benign Epidermal Inclusion Cyst involving the left lobe of the thyroid, which was successfully removed via hemithyroidectomy, resulting in resolution of symptoms. Clinical discussion: Epidermoid inclusion cysts are rare in the thyroid gland, with only sixteen reported cases worldwide. The cyst was diagnosed through ultrasound-guided fine needle aspiration and confirmed by surgical pathology. Treatment involves complete removal of the cyst and its capsule, which was successfully performed in this case under local anesthesia with sedation due to the patient’s medical history of COPD. Conclusion: it is important to consider the possibility of EIC when benign squamous cells are detected in a thyroid aspirate without any follicular cells. In such cases, hemithyroidectomy can be a successful management strategy.

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Section: Discussionmentioning

confidence: 99%

A case report of uncommon giant epidermal inclusion cyst found in the thyroid gland

Mousa,

Aljassem

2024

Annals of Medicine &Amp; Surgery

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“…Although it was suspected that the neck mass we encountered was a TGDC, according to the pathology report the specimen was an EIC. While commonly found on the skin, having an EIC on the thyroid gland is a rare finding [ 7 ]. According to a study published by the National Center for Biotechnology Information (NCBI) by Palacio et al in 2020, 85% to 90% of excised cysts are EICs [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…While commonly found on the skin, having an EIC on the thyroid gland is a rare finding [ 7 ]. According to a study published by the National Center for Biotechnology Information (NCBI) by Palacio et al in 2020, 85% to 90% of excised cysts are EICs [ 7 ]. However, the study also states that only 0.01% of EICs are found on mucosal sites, such as the oral cavity, and the majority are found on the trunk, neck, face, scrotum, and palmoplantar regions [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

Atypical Presentation of Epidermoid Inclusion Cyst in a 60-Year-Old Female: A Case Report

Salem¹,

Ahmed²,

Gupta³

et al. 2022

Cureus

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General surgeons frequently handle patients who present with an unknown neck mass. Due to the nature of diseases, medial neck soft tissue masses often manifest with variable etiologies and clinical signs and symptoms. Establishing a thorough evaluation of neck masses based on differential diagnoses is essential. The clinical evaluation of neck masses usually includes a thorough history and physical examination, advanced imaging techniques such as magnetic resonance imaging (MRI), ultrasonography, contrastenhanced computed tomography (CT), and fine-needle aspiration biopsy. From a surgeon's standpoint, proper knowledge of tissue structure, anatomy, and pathology, and applying fundamental surgical principles ensure a successful management of such lesions. This case report intends to reveal the pathological and clinical nature of an unknown neck mass in a 60-year-old female, which was postoperatively diagnosed as an epidermal inclusion cyst (EIC). This report also intends to indicate the significance of surgical intervention to prevent EIC complications and improve patient's life quality.

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