“…Since, clear cell RCC is the most frequent histological variant and is the most commonly found in patients with metastatic disease it is mandatory to explore the association of the EGFR pathways with progression of tumor variant [19,20]. Although there are mounting evidence that personalized therapy with applying targeted agents can often induce responses in patients we are aware of paucity of literature data on significance of its nuclear translocation.…”
Section: Consequences Of the Hypothesis And Discussionmentioning
“…Since, clear cell RCC is the most frequent histological variant and is the most commonly found in patients with metastatic disease it is mandatory to explore the association of the EGFR pathways with progression of tumor variant [19,20]. Although there are mounting evidence that personalized therapy with applying targeted agents can often induce responses in patients we are aware of paucity of literature data on significance of its nuclear translocation.…”
Section: Consequences Of the Hypothesis And Discussionmentioning
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