Epidemiology of viral hepatitis B and C in Punjab, Pakistan: a multicenter cross-sectional study, 2017-18

Khan, Amjad; Afzal, Saira; Yaqoob, Aashifa; Fatima, Razia; Haq, Mahboob Ul; Junaid, Khunsa; Nadir, Abdul

doi:10.12688/f1000research.20174.1

Cited by 12 publications

(9 citation statements)

References 20 publications

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“…The results when compared with a similar study[ 13 ] conducted in the general population of Pakistan almost correlated with young patients of up to 40 years. However, when comparing with a second study published in 2019 at an outreach center for screening and treatment in Pakistan,[ 14 ] it was found that most older age people (>61 years) were positive. It may be due to the inability of patients to seek medical attention after appearing of symptoms due to various reasons like finances, etc., eventually seeking medical help at a later stage.…”

Section: Discussionmentioning

confidence: 89%

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Predictive factors for acquiring HCV infection in the population residing in high endemic, resource-limited settings

Khan

Shah

Ashraf

2021

J Family Med Prim Care

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Background: In a country like Pakistan, a high prevalence of HCV persists due to a lack of awareness among the masses and the absence of adequate medical facilities in less privileged areas. Therefore, this study aimed to develop a risk-based screening tool based on the identification of predictive factors for HCV in the adult population in Karachi, Pakistan, which can later be validated for implementation. Methodology: A case-control study design was adopted and data was collected through an interview-based questionnaire from among 284 patients visiting the Family Medicine Department at The Indus Hospital, Karachi on whom the anti-HCV antibody test was conducted. Received data was then entered and analyzed using Statistical Package for the Social Sciences (SPSS) version 21.0. Result: Analysis indicated that in the entire cohort, marital status, employment status, history of being operated on in the past, family history of HCV infection, and body piercing were the factors significantly associated with positive HCV antibody. Results thus achieved show that the anti-HCV-positive rate was higher in ever married, employed, having had surgery, and family history of HCV infection (aOR: 2.42, 3.5, 2.04 and 2.5, P = 0.043, 0.002, 0.011 and 0.005, respectively). Conclusions: It is concluded that future research may be conducted enrolling the heterogeneous population to further probe the HCV burden and incidence in our society to initiate educational purposes. This goal can be achieved through commercial advertisements and free public lectures for disease prevention and better health awareness among the masses and the curers.

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Section: Discussionmentioning

confidence: 89%

“…Moreover, gender trends similar to our study were observed in another study that indicated women being infected more at a ratio of 1:3. [ 14 ]…”

Section: Discussionmentioning

confidence: 99%

Predictive factors for acquiring HCV infection in the population residing in high endemic, resource-limited settings

Khan

Shah

Ashraf

2021

J Family Med Prim Care

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“…The mean age of patients with positive and negative HBsAg was 48.7 ± 17.6 and 45.9 ± 21.22, respectively, and the difference was statistically significant. Studies report a strong relationship between age and HBsAg positivity (18,19). Nonetheless, a significant variation exists between regions and countries regarding the relationship of age groups with HBsAg positivity.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Seroprevalence of Hepatitis B Virus and Hepatitis C Virus in Reference Center Hospital in Turkey's Southeast Anatolia Among Patients Referred for Major or Minimally Invasive Surgery: Last Decade Experience in a Previously High Prevalence Area

Ekin

Uçmak

Atay

2021

Jundishapur J Microbiol

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Background: There is a high worldwide prevalence of chronic Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) infections, among the significant causes of liver-related morbidity and mortality. Objectives: We aimed to determine the prevalence of HBV and HCV in a referral center hospital in Southeast Anatolia among patients that applied for major or minimally invasive surgery. Methods: In a tertiary referral state hospital for general purposes, patients undergoing surgical procedures and serologic examinations for HBV and HCV were included in the study between January 2011 and September 2020. Results: In the general population, hepatitis B surface antigen (HBsAg) and anti-HBs were examined in 220,724 patients, and anti-HCV was examined in 186,017 patients. The mean age was 42.3 ± 20.2 years with a 51.8% male distribution. The frequency of positive HBsAg and anti-HCV in all patients was 9.4 and 0.9%, respectively. On the other hand, the frequency of positive HBsAg and anti-HCV was 4.2 and 0.7%, respectively, among patients admitted for a surgical procedure. The mean age was 46.1 ± 21.1 years with a slightly male predominance (54 vs. 46%). In this group, the frequency of positive HBsAg was higher in males (5.1%) while the lowest was in the 1 - 10 age range (0.4%) and the highest in the 41 - 50 age range (5.7%). Between 2011 and 2019, the prevalence of HBsAg positivity decreased from 6.4 to 4.0%, while anti-HCV positivity was similar in both genders, and its frequency increased with age. Conclusions: Between 2011 and 2020, the overall prevalence of HBV and HCV decreased in the Southeast Anatolia Region of Turkey.

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“…In every province, there are more than 28 districts which have a higher prevalence of hepatitis B. 9 This study aimed to assess the knowledge, attitude and practices of dental practitioners against Hepatitis B in district Faisalabad.…”

Section: Correspondencementioning

confidence: 99%

Knowledge, Attitude and Practices of Dental Practitioners against Hepatitis B in District Faisalabad

Rashid¹,

Habiba²,

Asif³

et al. 2021

JAFMDC

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Objective: To assess the knowledge, attitude and practices of dental practitioners against Hepatitis B in district Faisalabad. Methodology: This descriptive cross-sectional study was conducted from 1st August 2019 to 31st January 2020. Sixty four dental practitioners who are practicing in Allied hospital Faisalabad and DHQ hospital Faisalabad were recruited by using simple random sampling technique, included in this study. The data was collected through self-administered questionnaires. Results: Mean age ± SD of the respondents was 31.6±2.8 years. On account of assessing knowledge, 52 dentists strongly agreed for proper hand washing in the prevention of Hepatitis B. For using barriers like gloves, gown and masks, 56 of the respondents strongly agreed. For using puncture-resistant containers for sharp disposal, 25 of the respondents strongly agreed. For using protective eye wares 46 agreed. Fifty nine of the respondents strongly agreed for the proper sterilization of instruments in the prevention of Hepatitis B. On account of practices against Hepatitis B, 52 respondents were vaccinated against hepatitis B. Twelve were not vaccinated. Forty six out of 52 had completed the course of vaccination. Five out of 52 failed to recall the history of their vaccination but 6 did not completed the course. Conclusion: A good percentage of dental practitioners have been vaccinated against hepatitis B. However, there is a need to increase this percentage, so that maximum number of dentists that come in direct contact with the persons could be prevented against this fatal disease.

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Epidemiology of viral hepatitis B and C in Punjab, Pakistan: a multicenter cross-sectional study, 2017-18

Cited by 12 publications

References 20 publications

Predictive factors for acquiring HCV infection in the population residing in high endemic, resource-limited settings

Predictive factors for acquiring HCV infection in the population residing in high endemic, resource-limited settings

Evaluation of Seroprevalence of Hepatitis B Virus and Hepatitis C Virus in Reference Center Hospital in Turkey's Southeast Anatolia Among Patients Referred for Major or Minimally Invasive Surgery: Last Decade Experience in a Previously High Prevalence Area

Knowledge, Attitude and Practices of Dental Practitioners against Hepatitis B in District Faisalabad

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