Epidemiology of Trauma Deaths

Sauaia, Angela; Moore, Frederick A.; Moore, Ernest E.; Moser, Kathe S.; Brennan, Regina; Read, Robert; Pons, Peter T.

doi:10.1097/00005373-199502000-00006

Cited by 1,706 publications

(1,085 citation statements)

References 28 publications

Supporting

Mentioning

971

Contrasting

Unclassified

Order By: Relevance

“…Haemorrhage remains the leading cause of battlefield deaths [17] and the second leading cause of early death after civilian trauma [18]. Currently, a high proportion of military battlefield injuries are the consequence of explosive events, e.g.…”

Section: Forward (Pre-hospital) Resuscitationmentioning

confidence: 99%

Blast injury research models

Kirkman

Watts

Cooper

2011

Phil. Trans. R. Soc. B

105

View full text Add to dashboard Cite

Blast injuries are an increasing problem in both military and civilian practice. Primary blast injury to the lungs (blast lung) is found in a clinically significant proportion of casualties from explosions even in an open environment, and in a high proportion of severely injured casualties following explosions in confined spaces. Blast casualties also commonly suffer secondary and tertiary blast injuries resulting in significant blood loss. The presence of hypoxaemia owing to blast lung complicates the process of fluid resuscitation. Consequently, prolonged hypotensive resuscitation was found to be incompatible with survival after combined blast lung and haemorrhage. This article describes studies addressing new forward resuscitation strategies involving a hybrid blood pressure profile (initially hypotensive followed later by normotensive resuscitation) and the use of supplemental oxygen to increase survival and reduce physiological deterioration during prolonged resuscitation. Surprisingly, hypertonic saline dextran was found to be inferior to normal saline after combined blast injury and haemorrhage. New strategies have therefore been developed to address the needs of blast-injured casualties and are likely to be particularly useful under circumstances of enforced delayed evacuation to surgical care.

show abstract

Section: Forward (Pre-hospital) Resuscitationmentioning

confidence: 99%

Blast injury research models

Kirkman

Watts

Cooper

2011

Phil. Trans. R. Soc. B

105

View full text Add to dashboard Cite

show abstract

“…Haemorrhage is the leading cause of battlefield deaths [1] and the second leading cause after head injury of civilian trauma deaths [2]. Fluid resuscitation following trauma is frequently required to replace lost blood volume and optimize haemodynamics in order to maintain oxygen delivery to the tissues.…”

Section: Volume Resuscitation In Major Traumamentioning

confidence: 99%

Resuscitation and coagulation in the severely injured trauma patient

Midwinter

Woolley

2011

Phil. Trans. R. Soc. B

View full text Add to dashboard Cite

Developments in the resuscitation of the severely injured trauma patient in the last decade have been through the increased understanding of the early pathophysiological consequences of injury together with some observations and experiences of recent casualties of conflict. In particular, the recognition of early derangements of haemostasis with hypocoagulopathy being associated with increased mortality and morbidity and the prime importance of tissue hypoperfusion as a central driver to this process in this population of patients has led to new resuscitation strategies. These strategies have focused on haemostatic resuscitation and the development of the ideas of damage control resuscitation and damage control surgery continuum. This in turn has led to a requirement to be able to more closely monitor the physiological status, of major trauma patients, including their coagulation status, and react in an anticipatory fashion.

show abstract

“…RI an intrarenal artery is the most frequently used for clinical investigations because this measurement does not require estimations of the Doppler angle or the vessel crosssectional area. 5 Moreover, animal studies have shown that the renal Doppler RI is dependent on the perfusion pressure and is increased by hypotension in the presence of hypovolemia or normovolemic anemia.…”

Section: Introductionmentioning

confidence: 99%

Early detection with renal Doppler resistive index measurements of hemorrhagic shock in polytrauma patients

Yeslawath

2017

Int J Adv Med

View full text Add to dashboard Cite

Background: Poly trauma is a major cause of morbidity and mortality in both developed and developing countries. The aim was to investigate whether renal Doppler RI changes occur early with posttraumatic bleeding and whether the renal Doppler RI may enable accurate prediction of occult hypoperfusion and thus be predictive of the development of hemorrhagic shock in polytrauma patients.Methods: It was a prospective study involving patients admitted in the causality and evaluated by radiology department. Study was done in a period of 6 months from June 2016-December 2016. Renal Doppler RI was measured in 48 hemodynamically stable adult patients admitted in emergency because of polytrauma.Results: 26 patients developed hemorrhagic shock, and 22 did not. Hemorrhagic shock group, as compared with the nonhemorrhagic shock group, had higher renal Doppler RI (mean, 0.79±0.11 [standard deviation] vs 0.61±0.2; P<0.01), injury severity score (mean, 33±12 vs 25±9; P<0.01), and standard base excess (mean, -4.0mEq/L±4 vs 1mEq/L±3; P≤0.05) values. At logistic regression analysis, a renal Doppler RI greater than 0.9 was the only independent risk factor for progression to hemorrhagic shock (P<0.001).Conclusions: Renal Doppler RI measurement may represent a clinically useful non-invasive method for the early detection of occult hemorrhagic shock.

show abstract

Epidemiology of Trauma Deaths

Cited by 1,706 publications

References 28 publications

Blast injury research models

Blast injury research models

Resuscitation and coagulation in the severely injured trauma patient

Early detection with renal Doppler resistive index measurements of hemorrhagic shock in polytrauma patients

Contact Info

Product

Resources

About