Epidemiology of the Charcot Foot

Frykberg, Robert G.; Belczyk, Ronald

doi:10.1016/j.cpm.2007.10.001

Cited by 170 publications

(158 citation statements)

References 42 publications

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“…An association was also not found when the OR was calculated for ACF with BMI ≥ 25 kg/m 2 , which agrees with the results of other case control studies (12,20,27). The prevalence of ACF was 6% in the investigated population; whereas, in other published series, it varied from 0.1 to 12.9% as a function of the type of regional healthcare service sought, namely, general or specialized in diabetic foot care (6,7).…”

Section: Discussionmentioning

confidence: 81%

“…The risk factors for CF are not yet well established (7,11,12). The identification, prevention, and early manipulation of risk factors might delay the appearance and progression of CF.…”

Section: Introductionmentioning

confidence: 99%

“…The incidence of CF varies from 1.2 to 8.5 per 1,000 diabetic people per year (5), and its prevalence from 0.1% in the overall population of individuals with type 2 diabetes to 12.9% among the patients who seek diabetic foot care services (6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

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Risk factors for Charcot foot

Nóbrega

Aras

Netto

et al. 2015

Arch. Endocrinol. Metab.

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Objective: Diabetes mellitus is the main cause of Charcot neuroarthropathy and is clinically classified as follows: Charcot foot, acute Charcot foot (ACF) when there is inflammation, and inactive Charcot foot when inflammatory signs are absent. The aim of this study was to identify the risk factors for ACF in patients with type 2 diabetes mellitus. Materials and methods: A matched case-control study was conducted to assess the factors associated with acute Charcot foot from February 2000 until September 2012. Four controls for each case were selected 47 cases of ACF and 188 controls without ACF were included. Cases and controls were matched by year of initialization of treatment. Conditional logistic regression was used to estimate matched odds ratios (ORs) and 95% confidence intervals (95% CIs). Results: In multivariate analysis, patients having less than 55 years of age (adjusted OR = 4.10, 95% CI = 1.69 -9.94), literate education age (adjusted OR = 3.73, 95% CI = 1.40 -9.92), living alone (adjusted OR = 5.84, 95% CI = 1.49 -22.86), previous ulceration (adjusted OR = 4.84, 95% CI = 1.62 -14.51) were at increased risk of ACF. However, peripheral arterial disease (adjusted OR = 0.16, 95% CI = 0.05 -0.52) of 6.25 (1.92 -20.0) was a protective factor. Discussion: The results suggest that PCA in type 2 diabetes primarily affects patients under 55 who live alone, are literate, and have a prior history of ulcers, and that peripheral arterial disease is a protective factor. Arch Endocrinol Metab.2015;59(3):226-30

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Section: Discussionmentioning

confidence: 81%

“…The risk factors for CF are not yet well established (7,11,12). The identification, prevention, and early manipulation of risk factors might delay the appearance and progression of CF.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Risk factors for Charcot foot

Nóbrega

Aras

Netto

et al. 2015

Arch. Endocrinol. Metab.

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“…21 Also in 1883, Charcot and his colleague Fere described involvement of the foot in patients with tabes dorsalis, coining the term "pied tabetique" which has come to be known as Charcot's foot. 18 While syphilis was the most common cause of Charcot's joint in the mid to late 19 th century, William Jordan recognized the association between diabetes mellitus and neuropathic arthropathies in 1936. 16,20 Currently, Charcot's joint is believed to be present in up to 35% of patients with diabetic neuropathy, but this number may be an underestimate, since Charcot's joint is difficult to diagnose.…”

Section: Charcot's Jointmentioning

confidence: 99%

“…16,17 The loss of sensation and pain perception that occurs in patients with arthropathies results in continued weight bearing and stress of the weakened joints, leading to bone fractures and further destruction of the joint and soft tissue. 18,19 After a period of acute inflammation, structural weakening occurs followed by eventual healing or consolidation, at which point the bone is deformed. 20 However, the involvement of the small bones and joints of the foot in tabetic arthropathies was not described until 1881 at the 7 th International Medical Congress by English physician Herbert W. Page (though not fully recognized until 1883 when presented to the Clinical Society of London.)…”

Section: Charcot's Jointmentioning

confidence: 99%