Sleep Disorders in Women 2013
DOI: 10.1007/978-1-62703-324-4_2
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Epidemiology of Sleep Disorders in Women

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(2 citation statements)
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“…Estrogen influences the dopaminergic system and not only up-regulates the receptors but also the reuptake mechanism. Further, it also reduces the catabolism of dopamine by inhibitory influence on the Catechol-O-methyltransferase (COMT) enzyme [82]. Thus, it increases the availability of dopamine in the nigro-striatal pathway yet it also increases the reuptake.…”
Section: Restless Legs Syndromementioning
confidence: 99%
See 1 more Smart Citation
“…Estrogen influences the dopaminergic system and not only up-regulates the receptors but also the reuptake mechanism. Further, it also reduces the catabolism of dopamine by inhibitory influence on the Catechol-O-methyltransferase (COMT) enzyme [82]. Thus, it increases the availability of dopamine in the nigro-striatal pathway yet it also increases the reuptake.…”
Section: Restless Legs Syndromementioning
confidence: 99%
“…As we have already discussed, sleep difficulties in this group are in part related to vasomotor symptoms. This could be one reason why WED/RLS symptoms have been correlated with the presence of vasomotor symptom among menopausal women in many studies [11,83]. However, one of the recent studies did not find any difference between the sleep difficulties across genders, despite higher prevalence of RLS among females [84].…”
Section: Restless Legs Syndromementioning
confidence: 99%