Epidemiology of Rotavirus Infection in Children Less than Five Years in Omdurman Paediatric Hospital, Khartoum, Sudan

Abstract

Objective: Our objective is to study epidemiology of rotavirus infection in children less than five years during one year in Omdurman Paediatric Hospital. Materials and Methods:The study design was a setting-based study. The required data were obtained by reviewing records of a year in the hospital. Results: The findings revealed that, the total cases of rotavirus infection was 1563, majority of cases occurred among age group 1-12 months 642(41%). About 899(57.5%) of cases were males while 664(42.5%) were females. High percentage 520(33.3%) of diagnosed children came from Umbda. Most of rotavirus cases occurred during April168 (10.7%) and May 158(10.1%), Mild dehydration was found in 1121(71.7%) of cases while 320(20.5%) of patients suffered from severe dehydration. Oral rehydration therapy (ORT) were given to 1120(71.7%) of patients as treatment, intravenous fluids (IVF) to 334(21.3%) and ORT & IVF to 109 (7%). A lot of cases 1110(71%) were improved after received the treatment, 9(0.6%) were died and the rest were still suffering from the clinical features. Conclusion: The study concluded that rotavirus represents a public health problem among children less than five which and effective control measures are needed to minimize this problem.

The Accuracy of Elisa Versus Latex Agglutination Tests in Diagnosis of Rotavirus Acute Gastroenteritis and the Clinical Usefulness of C- Reactive Protein in Iraqi Children

“…In this study, the minimum age of infected children was (1) months while maximum age was seven years and the mean age was 1.23 years. The reported age come in line with that reported in local [13] and international studies in Sudan [2], India [14] and Taiwan [15]. In the current study, males represent (62.5%) which come by findings in Iraq [13,16], India [14], and Sudan [2].…”

“…The reported age come in line with that reported in local [13] and international studies in Sudan [2], India [14] and Taiwan [15]. In the current study, males represent (62.5%) which come by findings in Iraq [13,16], India [14], and Sudan [2]. The minimum CRP level (6 mg/dl), the maximum was (96 mg/dl) and the mean (31.72 ± 30.58 mg/dl).…”

“…Rotavirus is a member of the genus Rotavirus, family Reoviridae, and it is an important causative agent of acute gastroenteritis in children and many young animal species worldwide [1]. There are five species of this virus, referred to as A, B, C, D, and E. Rotavirus A, the most common species, causes more than 90% of infections in humans [2]. By the age five, nearly every child in the world has been infected with rotavirus at least once [3].…”

“…The disease causes many symptoms mainly diarrhoea, nausea, malaise, headache, abdominal cramping, fever and vomiting. However, the infection can be symptomless sometimes [2]. The World Health Organization (WHO) has encouraged the introduction of a rotavirus vaccine into national immunisation programs, particularly in poorer countries [6].…”

A Review of Sudan’s Major Food-Borne Viral and Fungal Diseases

“…In Sudan, viral genotyping was studied based on the viral proteins (VP4 and VP7) by nested PCR and gene sequencing results showed the VP7 predominant G class was G1 (8). Two epidemiological studies conducted on under-5-year-old children infected with rotavirus in Omdurman Pediatric Hospital, Sudan; The first was a setting-based study over one year, which concluded that rotavirus represents a public health problem among Sudanese children younger than five years and that effective control procedures are essential to reduce this problem (9). The other study found that rotavirus prevalence was 25% in children under the age of five, and that rotavirus vaccine, accurate and routine diagnosis of acute child diarrheal infection aids in accurate management, preventing antibiotic use, and reducing the prevalence in vulnerable children (10).…”