Epidemiology of rotavirus-associated hospital admissions in the province of Ferrara, Italy

Marsella, Maria; Raimondi, Licia; Bergamini, Mauro; Sprocati, Monica; Bigi, Ettore; Sanctis, Vincenzo De; Borgna‐Pignatti, Caterina; Gabutti, Giovanni

doi:10.1007/s00431-009-0942-z

Cited by 15 publications

(15 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other authors [18] [22] have confirmed this finding. Physicians recorded the ICD code 00861 on the main discharge diagnosis form in only 23.14% of RV-positive cases with community-acquired infection, and on the secondary discharge diagnosis form in 42.12%; the RV code was attributed to only 65.26% of RV-positive cases.…”

Section: Discussionsupporting

confidence: 75%

“…The disease burden was seen to be heavy and similar to 9 the percentages reported in other Italian studies [17] [18]. Giaquinto et al [5] reported a heavier impact; they found that 40% of acute enteritis cases in children under 5 years were caused by RV, the virus being responsible for 68% of hospitalisations, 61% of ED examinations and 33% of cases of primary care in the Padua area (Northern Italy).…”

Section: Discussionsupporting

confidence: 73%

See 1 more Smart Citation

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

Panatto

Amicizia

Giacchino

et al. 2011

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

Purpose We evaluated the rates of gastroenteritis admissions to the emergency department and of rotavirusrelated hospitalisations in children ≤5 years in 2006 at an Italian paediatric hospital; we calculated the number of rotavirus cases avoidable through the universal vaccination of children.Methods Epidemiological data were extracted from the Data Elaboration Centre. To calculate the hospitalisation rate due to rotavirus, the virus was sought in the faeces of children hospitalised for acute gastroenteritis by means of rapid immunochromatographic assay.Results Emergency department admissions due to gastroenteritis numbered 2396 (11.58% of total admissions).Of these, 276 children (11.52%) were examined and then sent home; 1286 (53.67%) were kept in short observation and 776 (32.38%) were hospitalised. In 27.83% of hospitalised cases, the rotavirus test proved positive. The RV hospitalization rate was 55 per 10000 children ≤5 years in Genoa in 2006. In 85.6% of hospitalised patients with community-acquired rotavirus infection, the disease was severe. ConclusionsThe number of avoidable cases confirmed that the vaccination of children ≤1 year of age could reduce the burden of rotavirus infection, especially with regard to hospitalisation (45 per 10000 children ≤5 years) and admissions to short observation (85 per 10000), generating benefits for Italian healthcare system.

show abstract

Section: Discussionsupporting

confidence: 75%

Section: Discussionsupporting

confidence: 73%

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

Panatto

Amicizia

Giacchino

et al. 2011

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

show abstract

“…1 Mean patient age during all episodes of diarrhea in both racecadotril (black) and loperamide (white) treatment groups infections, including those caused by viruses, bacteria, or parasites [17,18]. Viruses are more important in infants (rotaviruses) [19][20][21] and cause community foodand water-borne gastroenteritis (noroviruses) in all age groups [22,23]. In health-care facilities, transmission can additionally occur through hand transfer of the virus to the oral mucosa via contact with materials, vomits, and environmental surfaces that have been contaminated with either feces or vomits.…”

Section: Discussionmentioning

confidence: 99%

Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes

Gallelli

Colosimo²,

Tolotta

et al. 2009

Eur J Clin Pharmacol

View full text Add to dashboard Cite

show abstract

“…The 20 These costs are estimated for all hospitalizations which were complicated by a hospitalacquired rotavirus infection. To give an estimation of the excess of cost due to nosocomial rotavirus, our results were compared with the cost of a standard hospitalization in which rotavirus was not implicated.…”

Section: Figures 4 Andmentioning

confidence: 99%

Hospital-acquired rotavirus infections in Spain over a ten-year period (1998-2007)

Gil-Prieto¹,

M²,

Al³

et al. 2009

Human Vaccines

View full text Add to dashboard Cite

IntroductionAcute gastroenteritis poses an important health problem in developing countries and a considerable economic burden in developed countries, taking into account not only direct costs but also indirect costs, such us days of work lost by parents. 1,2 Rotavirus is regarded as the most frequent cause of acute gastroenteritis, with 3.6 million cases per year in children up to five years of age in Europe, 3,4 and it imposes a median hospitalization cost of 1,417 Euros among EU-25 Member States.Rotavirus can survive for weeks in water and on different surfaces. Thus, it is easily transmitted through contaminated surfaces, particularly in kindergartens and pediatric units in hospitals. Hygienic preventive measures are not effective in stopping transmission, hence the high morbidity in developed countries.Real incidence of rotavirus infection is underestimated because there is not a specific epidemiological surveillance system. It is estimated that a significant percentage (20 to 60%) of hospital admissions due to acute diarrhea in children are caused by rotavirus, most of these in children younger than six months. Although rotavirusrelated mortality in developed countries is low, the morbidity and associated consumption of health care resources are considered to be high. 5Gastrointestinal infections, especially those caused by rotavirus, are considered among the most frequent cause of nosocomial infection in pediatric units. In contrast to community-acquired rotavirus, nosocomial infections mainly affect breast-fed babies under six months of age.5 Symptoms appear two to six days after hospitalization. A high percentage of non-symptomatic carriers contribute to spread of the infection. The risk of nosocomial infection is associated with lengthy hospitalizations, low birth weight, presence of chronic pathology, immunocompromise and malnutrition. [5][6][7] This study was performed to assess the burden of nosocomial rotavirus infection in Spain during a 10-year period. ResultsA total of 10,990 cases of rotavirus disease (ICD 9 CM codes 008.61; secondary diagnosis position) in hospitalized children five years of age and younger were reported during the 10-year Hospital-acquired rotavirus infections in spain over a ten-year period (1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007) Ruth Gil-prieto, Background and objectives: To analyze the epidemiology and burden of rotavirus infections amongst hospitalized children up to 5 years of age in spain over a 10-year period (1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007).Results: During the study period (1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007), a total of 10,990 cases of rotavirus disease mentioned as a secondary diagnosis were recorded (annual incidence of 59.02 cases per 100,000 people and 0.45 cases per 100 admissions). The average patient age was 9.8 months (sD 9.3), with 71% of the patients younger than 12 months of age. The mortality rate for children hospitalized for other primary causes, with rotavirus gastroenteritis as a...

show abstract

Epidemiology of rotavirus-associated hospital admissions in the province of Ferrara, Italy

Abstract: The results of this study contribute to the awareness of rotavirus epidemiology in Italy and underline the potential impact of rotavirus vaccination in our province.

Cited by 15 publications

References 26 publications

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes

Hospital-acquired rotavirus infections in Spain over a ten-year period (1998-2007)

Contact Info

Product

Resources

About