Epidemiology of Rheumatoid Arthritis in Southern Albania

Abstract

Objectives:The aim of this study was to assess the prevalence, incidence and the burden of rheumatoid arthritis (RA) in the Southern Albania.Material and Methods:This is an epidemiologic observational study with cross-sectional analyses of all patients with RA who lived in Southern Albania during the 1995-2011 years. The RA prevalence, incidence and disability-adjusted life years (DALY) were assessed.Results:During the 1995-2011 years, 194 patients (154 females and 40 males) with RA living in Southern Albania were identified. The prevalence of RA in 2011 was 0.25% in general population and 0.34% in adult (>14 years) population. The incidence of RA in 2011 was 0.012% (12 new cases per 100000 inhabitants) and 0.016% (16 new cases per 100000 adults). The prevalence increased (from 0.036% in 1996 to 0.25% in 2011) and the incidence did not change over the study period. The mortality was 3.2% (n=7 deaths). The DALY due to RA was 823 years per 100000 inhabitants during 1995-2011 years.Conclusion:RA in Southern Albania has a prevalence of 0.25 % and an annual incidence of 0.012% in the general population in 2011. RA was responsible for a considerable burden on the health of population during the 1995-2011 years.

RNA‐seq analysis reveals different gene ontologies and pathways in rheumatoid arthritis and Kashin–Beck disease

“…Rheumatoid arthritis (RA) is a systemic autoimmune disease involving the activation of inflammatory cells, synovial hyperplasia and destruction of cartilage and bone. It is postulated as having a complex environmental and genetic basis involving an unknown number of genes . A complete loss of mobility and functioning can be the final outcome of the disease.…”