Background: Breast cancer is the most often diagnosed disease and the main cause of death between females globally. Different chemotherapeutic are used, such as doxorubicin or epirubicin in combination with cyclophosphamide, and paclitaxel (Taxol) or docetaxel in combination with carboplatin Aims: the study aimed to evaluate effect of implementing bundle of care on breast cancer patients paclitaxel induced peripheral neuropathy and quality of life. Methods