Epidemiology of methicillin-resistant Staphylococcus aureus in dairy herds

Devriese, Luc; Hommez, J.

doi:10.1016/s0034-5288(18)33549-5

Cited by 124 publications

(68 citation statements)

References 17 publications

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“…In 1975 the first report on MRSA isolated from cows with mastitis was published (Devriese and Hommez, 1975). This sporadic case was followed by only a few other cases in the next 25 years.…”

Section: Emergence Of La-mrsa In Livestock and Other Animalsmentioning

confidence: 99%

Livestock-associated methicillin-resistant Staphylococcus aureus in animals and humans

Graveland

Duim

Duijkeren

et al. 2011

International Journal of Medical Microbiology

259

179

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Section: Emergence Of La-mrsa In Livestock and Other Animalsmentioning

confidence: 99%

Livestock-associated methicillin-resistant Staphylococcus aureus in animals and humans

Graveland

Duim

Duijkeren

et al. 2011

International Journal of Medical Microbiology

259

179

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“…25 Devriese reported 68 MRSA isolates from mastitis milk samples originating in 20 Belgian dairy herds, and suggested that these strains might have come from a single human source. Transmission of 'human' strains of S. aureus to farm animals was also reported by Moeller et al 26 in 1963.…”

Section: Methicillin-resistant Staphylococci In Animalsmentioning

confidence: 99%

Staphylococci in animals: prevalence, identification and antimicrobial susceptibility, with an emphasis on methicillin-resistant Staphylococcus aureus

Rich¹

2005

British Journal of Biomedical Science

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Staphylococci form part of the normal flora of man and a wide variety of animals. Some staphylococcal species also cause a wide variety of pyogenic infections. The main pathogenic staphylococcus in man is Staphylococcus aureus. Increasingly, methicillin-resistant S. aureus (MRSA) has been a problem in the healthcare setting. Reports of MRSA in animals have been infrequent; however, evidence suggests that MRSA is being isolated increasingly from animals, in particular household pets and other companion animals. This article reviews the prevalence of pathogenic staphylococci in animals, with an emphasis on the emergence of MRSA as a possible animal pathogen.

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“…Since the initial description in 1961, MRSA has spread globally with a small number of specific clones, including multilocus sequence types 239 (ST239), ST22, and ST8, causing the majority of the burden of disease (1, 2). Since the late 1990s, the role that both livestock and companion animals play as reservoirs and vectors for transmission of MRSA has become clearer (3–5). This relationship seems to be bidirectional, with human origins for the ST5 poultry lineage (6) and clonal complex 398 (CC398) originally infecting humans, jumping to livestock, and then back to humans (7, 8).…”

Section: Introductionmentioning

confidence: 99%

A Shared Population of Epidemic Methicillin-Resistant Staphylococcus aureus 15 Circulates in Humans and Companion Animals

Harrison

Weinert

Holden

et al. 2014

mBio

100

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Methicillin-resistant Staphylococcus aureus (MRSA) is a global human health problem causing infections in both hospitals and the community. Companion animals, such as cats, dogs, and horses, are also frequently colonized by MRSA and can become infected. We sequenced the genomes of 46 multilocus sequence type (ST) 22 MRSA isolates from cats and dogs in the United Kingdom and compared these to an extensive population framework of human isolates from the same lineage. Phylogenomic analyses showed that all companion animal isolates were interspersed throughout the epidemic MRSA-15 (EMRSA-15) pandemic clade and clustered with human isolates from the United Kingdom, with human isolates basal to those from companion animals, suggesting a human source for isolates infecting companion animals. A number of isolates from the same veterinary hospital clustered together, suggesting that as in human hospitals, EMRSA-15 isolates are readily transmitted in the veterinary hospital setting. Genome-wide association analysis did not identify any host-specific single nucleotide polymorphisms (SNPs) or virulence factors. However, isolates from companion animals were significantly less likely to harbor a plasmid encoding erythromycin resistance. When this plasmid was present in animal-associated isolates, it was more likely to contain mutations mediating resistance to clindamycin. This finding is consistent with the low levels of erythromycin and high levels of clindamycin used in veterinary medicine in the United Kingdom. This study furthers the “one health” view of infectious diseases that the pathogen pool of human and animal populations are intrinsically linked and provides evidence that antibiotic usage in animal medicine is shaping the population of a major human pathogen.

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Epidemiology of methicillin-resistant Staphylococcus aureus in dairy herds

Cited by 124 publications

References 17 publications

Livestock-associated methicillin-resistant Staphylococcus aureus in animals and humans

Livestock-associated methicillin-resistant Staphylococcus aureus in animals and humans

Staphylococci in animals: prevalence, identification and antimicrobial susceptibility, with an emphasis on methicillin-resistant Staphylococcus aureus

A Shared Population of Epidemic Methicillin-Resistant Staphylococcus aureus 15 Circulates in Humans and Companion Animals

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