Epidemiology of lymphogranuloma venereum in New South Wales, 2006–2015

Abstract

Aim To describe the epidemiology of lymphogranuloma venereum (LGV) in New South Wales (NSW) from 2006 to 2015. Methods LGV notification data between 2006 and 2015 from New South Wales were analysed to describe time trends in counts and rates by gender, age group and area of residence, as well as anatomical sites of infection. A positivity ratio was calculated using the number of LGV notifications per 100 anorectal chlamydia notifications per year. Data linkage was used to ascertain the proportion of LGV cases that were co-infected with HIV. Results There were 208 notifications of LGV in NSW from 2006 to 2015; all were among men, with a median age of 42 years, and half were residents of inner-city Sydney. Annual notifications peaked at 57 (1.6 per 100,000 males) in 2010, declined to 16 (0.4 per 100,000 males) in 2014, and then increased to 34 (0.9 per 100,000 males) in 2015. Just under half (47.4%) of LGV cases were determined to be co-infected with HIV. Conclusion The number of LGV notifications each year has not returned to the low levels seen prior to the peak in 2010. Continued public health surveillance is important for the management and control of LGV.

Clinical and Epidemiological Characterization of Lymphogranuloma Venereum in a Sexually Transmitted Diseases Clinic in Lisbon, 2001 to 2020

“…Contrary to the results of most studies, 12,13 the majority (63%) of our LGV cases were detected in HIV-negative patients. Accordingly, increasing proportions of HIV-negative among LGV-positives have been described 4,14 .…”

Prevalence of anatomically specific infections with Chlamydia trachomatis among men who have sex with men in China: protocol for a nationwide cross-sectional study as part of Disease Burden Surveillance of Infections with Chlamydia (DBSIC)

“…The study also aims to investigate the specific genotypes associated with the LGV strains in this population in China. LGV outbreaks or increasing prevalence of LGV has appeared during the last decade in many countries in North America, Europe and the Pacific in the form of proctocolitis among MSM 13–16. However, no cases with LGV-related proctocolitis or genotypes associated with LGV have been reported from clinic practice or epidemiological studies2–5 since a case was reported by us in 2007 17.…”

Investigating the decline in Lymphogranuloma venereum diagnoses in men who have sex with men in the United Kingdom since 2016: an analysis of surveillance data

“…1 Increases in LGV were first seen among gay, bisexual and other men who have sex with men (MSM) in Western Europe in 2003, and outbreaks were subsequently reported in other high-income countries, including Australia. 2 Diagnoses in the UK and across Europe rose between 2004 and 2016, with the highest European rates seen in the UK. 3 Surveillance of LGV in the UK showed a consistent ongoing pattern of the infection being concentrated in MSM living in London, many of whom were co-infected HIV and other STIs.…”