Epidemiology of lumbar osteoporosis and osteoarthritis and their causal relationship—is osteoarthritis a predictor for osteoporosis or vice versa?: The Miyama study

Yoshimura, Nagahisa; Muraki, Shigeyuki; Oka, Hiroyuki; Mabuchi, Akihiko; Kinoshita, Hiroki; Yosihda, M.; Kawaguchi, Hiroshi; Nakamura, Kozo; Akune, Toru

doi:10.1007/s00198-008-0771-3

Cited by 27 publications

(17 citation statements)

References 29 publications

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“…Two Japanese studies on lumbar spine radiographic OA, using a higher Kellgren-Lawrence (K-L) grade (≥3), reported point prevalences of 40%-75% in the 60–69 year olds to 80%-90% in the 80+ age group [33,35]. …”

Section: Resultsmentioning

confidence: 99%

What is the prevalence of musculoskeletal problems in the elderly population in developed countries? A systematic critical literature review

2012

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BackgroundThe proportion of older people will be tripled by the year 2050. In addition, the incidence of chronic musculoskeletal (MSK) conditions will also increase among the elderly people. Thus, in order to prepare for future health care demands, the magnitude and impact of MSK conditions from this growing population is needed. The objective of this literature review is to determine the current prevalence of MSK disorders in the elderly population.MethodsA systematic literature search was conducted in Pubmed on articles in English, published between January 2000 and July 2011. Studies from developed countries with prevalence estimates on elderly people (60+) on the following MSK conditions were included: Non-specific extremity pain, rheumatoid arthritis, osteoarthritis, osteoporosis, and back pain. The included articles were extracted for information and assessed for risk of bias.ResultsA total of 85 articles were included with 173 different prevalence estimates. Musculoskeletal disorders are common in the elderly population, but due to heterogeneity of the studies, no general estimate on the prevalence of MSK can be determined. Women report more often MSK pain than men. Overall, prevalence estimates either remain fairly constant or increase slightly with increasing age, but with a tendency to decrease in the oldest (80+) people.ConclusionsMusculoskeletal disorders remain prevalent in the elderly population. Given the increasing proportion of elderly population in the world population and the burden of MSK diseases among the elderly people, efforts must be made to maintain their functional capacity for as long as possible through optimal primary and secondary health care.

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Section: Resultsmentioning

confidence: 99%

What is the prevalence of musculoskeletal problems in the elderly population in developed countries? A systematic critical literature review

2012

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“…8 Further studies with a prospective design are needed to clarify this issue, because osteoarthritis may spuriously influence BMD measurements, but on the other hand, a true association between bone mass and osteoarthritis has also been suggested. 40 …”

Section: Discussionmentioning

confidence: 97%

Relationship of sclerostin and secreted frizzled protein polymorphisms with bone mineral density

et al. 2011

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“…Most of these patients suffer from osteoporosis [36, 37]. Osteoporosis likely reduces both the stiffness and the ultimate shear strength of the pars interarticularis.…”

Section: Discussionmentioning

confidence: 99%

Anterior shear strength of the porcine lumbar spine after laminectomy and partial facetectomy

et al. 2010

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Degenerative lumbar spinal stenosis is the most common reason for lumbar surgery in patients in the age of 65 years and older. The standard surgical management is decompression of the spinal canal by laminectomy and partial facetectomy. The effect of this procedure on the shear strength of the spine has not yet been investigated in vitro. In the present study we determined the ultimate shear force to failure, the displacement and the shear stiffness after performing a laminectomy and a partial facetectomy. Eight lumbar spines of domestic pigs (7 months old) were sectioned to obtain eight L2–L3 and eight L4–L5 motion segments. All segments were loaded with a compression force of 1,600 N. In half of the 16 motion segments a laminectomy and a 50% partial facetectomy were applied. The median ultimate shear force to failure with laminectomy and partial facetectomy was 1,645 N (range 1,066–1,985) which was significantly smaller (p = 0.012) than the ultimate shear force to failure of the control segments (median 2,113, range 1,338–2,659). The median shear stiffness was 197.4 N/mm (range 119.2–216.7) with laminectomy and partial facetectomy which was significantly (p = 0.036) smaller than the stiffness of the control specimens (median 216.5, 188.1–250.2). It was concluded that laminectomy and partial facetectomy resulted in 22% reduction in ultimate shear force to failure and 9% reduction in shear stiffness. Although relatively small, these effects may explain why patients have an increased risk of sustaining shear force related vertebral fractures after spinal decompression surgery.

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Epidemiology of lumbar osteoporosis and osteoarthritis and their causal relationship—is osteoarthritis a predictor for osteoporosis or vice versa?: The Miyama study

Abstract: OP in women appears to reduce the future incidence of OA at the lumbar spine.

Cited by 27 publications

References 29 publications

What is the prevalence of musculoskeletal problems in the elderly population in developed countries? A systematic critical literature review

What is the prevalence of musculoskeletal problems in the elderly population in developed countries? A systematic critical literature review

Relationship of sclerostin and secreted frizzled protein polymorphisms with bone mineral density

Anterior shear strength of the porcine lumbar spine after laminectomy and partial facetectomy

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