Epidemiology of Intrauterine Fetal Deaths: A Study In Tertiary Referral Centre In Uttarakhand

Choudhary, Dr Anjali; Gupta, D

doi:10.9790/0853-13320306

Cited by 32 publications

(51 citation statements)

References 6 publications

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“…This is in accordance with the study by Singh neetu7 et al in which the maximum IUD were in the age group 21-25 (45.71%) followed by age group 26-30 (36.19%). Similar results were found in the study by Choudhary A et al 6 also. Pregnancy in extremes of age group and obesity in reproductive age group is uncommon in our setup.…”

Section: Discussionsupporting

confidence: 82%

“…Incidence of IUFD at our centre was found to be 50 per 1000 deliveries which is in accordance to study conducted by ChoudharyAnjali et al 6 which revealed prevalence as 49 per 1000 live births. In a Retrospective study by SinghNeetu et al 7 incidence of IUFD reported was 40 per 1000.…”

Section: Discussionsupporting

confidence: 77%

“…In the study by SinghNeetu 7 et al it was 54%in males and 46%in females. Whereas in study by Choudhary A et al 6 there were 58 male babies v/s 47 female babies. 60% IUFD were found among fetuses weighing 2000 grams or less.…”

Section: Discussionmentioning

confidence: 98%

See 2 more Smart Citations

Intrauterine fetal demise-a tragic event: a study of its epidemiology, causes and methods of induction

Dave

Patidar

Goyal

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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Section: Discussionsupporting

confidence: 82%

Section: Discussionsupporting

confidence: 77%

See 1 more Smart Citation

Intrauterine fetal demise-a tragic event: a study of its epidemiology, causes and methods of induction

Dave

Patidar

Goyal

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…The rate of IUFD cases are different between countries, cities, even differ from year to year, this variance due to the fact that there are several factors such as antenatal care service quality, the argument between researchers in determining gestational age and weight of the fetus in the definition of IUFD [4] [7]. Several studies were carried out to define the risk factors caused IUFD, these factors di- As regards to maternal factors associated with fetus death, several studies addressed the relation between maternal age and IUFD, where childbearing women younger than 20 and older than 40 years are more likely to have stillbirth than women in group age 24 -35 years and the problem become more obvious in women aged ≥ 40 years [12] [13].…”

Section: Discussionmentioning

confidence: 99%

Conditions Associated with Intrauterine Fetal Demise (IUFD) in Pregnant Women at King Abdulaziz University (KAUH). A Five-Year Experience

Kafy¹,

Oraif²

2017

OJOG

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Background: Intrauterine fetal demise is the death of the fetus after twenty week of gestation but before the onset of labor. In more than 50% of cases, the etiology of antepartum fetal death is not known or cannot be determined. Several factors attributed to the risk of IUFD. This study aimed to determine the incidence of IUFD, as well as associated conditions. Method: This retrospective study enrolled all pregnant women who attending at KAUH between 2011 and 2015. Results: During the last five years 248 verified IUFD cases were reported, the mean age was 30.59. Saudi nationality represented by 27 %. PET was represented 17.7% and congenital malformation was represented by 7.3% as risk factors. Regarding the mode of delivery SVD was 58.9% followed by CS 28.6. Conclusion: Stillbirth is an unfavorable event, there are several factors (maternal, fetal & placenta) associated with IUFD. Providing good level of antenatal care helped in reducing IUFD incidence.

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“…A number of investigations, including autopsy, examination of the placenta, amniocentesis and tests on blood from the mother and child, have been recommended in the diagnostic evaluation of IUFD [12][13][14][15]. The proportion of IUFDs in which no identifiable cause can be determined ranges from 12 to 50% and may be related to environmental factors [16][17][18]. Notably, increased consumption of dietary choline during pregnancy can improve biomarkers of choline metabolism.…”

Section: Discussionmentioning

confidence: 99%

Polymorphic variants of genes involved in choline pathway and the risk of intrauterine fetal death

Drews¹,

Różycka²,

Barlik³

et al. 2017

Ginekol Pol

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Objectives: Choline and folate metabolism disturbances may be involved in the occurrence of intrauterine fetal death (IUFD). The proper activity of this metabolism could be determined by genetic variants involved in choline pathway e.g. CHKA (gene encoding choline kinase α), PCYT1A (gene encoding CCTα) and CHDH (gene encoding choline dehydrogenase). Our study aimed at determining the genotype and allele frequencies of CHKA rs7928739, PCYT1A rs712012, PCYT1A rs7639752, CHDH rs893363 and CHDH rs2289205 polymorphisms in mothers with IUFD occurrence. Material and methods:The study involved 76 mothers with IUFD occurrence and 215 mothers of healthy children. Genetic analysis was performed with the use of PCR/RFLP method. Results:The frequency of genotypes and alleles of studied polymorphisms was similar in both groups. The study revealed no association of PCYT1A, CHKA and CHDH polymorphisms in analysed groups of women. While evaluating the co-existence of analysed polymorphisms statistically significant correlation was revealed. Co-existence of CHKA rs7928739 AC/CHDH rs2289205 AA genotypes was observed statistically more frequently in the study group than in the control group (p = 0,031). Conclusions:There is no correlation between single CHKA rs7928739, PCYT1A rs712012, PCYT1A rs7639752, CHDH rs893363 and CHDH rs2289205 polymorphisms and the incidence of intrauterine fetal death. However, revealed statistically significant difference between co-existence of CHKA rs7928739 AC/CHDH rs2289205 AA genotypes between study groups suggest the need of further analysis.

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Epidemiology of Intrauterine Fetal Deaths: A Study In Tertiary Referral Centre In Uttarakhand

Cited by 32 publications

References 6 publications

Intrauterine fetal demise-a tragic event: a study of its epidemiology, causes and methods of induction

Intrauterine fetal demise-a tragic event: a study of its epidemiology, causes and methods of induction

Conditions Associated with Intrauterine Fetal Demise (IUFD) in Pregnant Women at King Abdulaziz University (KAUH). A Five-Year Experience

Polymorphic variants of genes involved in choline pathway and the risk of intrauterine fetal death

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