Epidemiology of inpatient stay in Parkinson’s disease in the United States: Insights from the Nationwide Inpatient Sample

Mahajan, Abhimanyu; Balakrishnan, Poojitha; Patel, Achint; Konstantinidis, Ioannis; Nistal, Dominic A; Annapureddy, Narender; Poojary, Priti; Nadkarni, Girish N.; Sidiropoulos, Christos

doi:10.1016/j.jocn.2016.03.005

Cited by 34 publications

(31 citation statements)

References 9 publications

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“…The respiratory tract and the urinary tract were the two most common infection sites among PD patients in this and other studies [ 5 , 10 ]. Our study revealed that pneumonia is the leading cause of sepsis-related mortality in PD patients; in contrast, urinary tract infections had the highest survival rates.…”

Section: Discussionsupporting

confidence: 68%

“…Therefore, infection is a common problem in patients with advanced PD. Several nationwide studies have demonstrated that respiratory tract and urinary tract infections are the leading cause of acute emergency admission in PD patients [ 3 – 5 ]. Since the number of PD patients is expected to double by the year 2030, how to manage infected PD patients in the emergency department (ED) is becoming an important issue [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

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Manifestations and Outcomes of Patients with Parkinson’s Disease and Serious Infection in the Emergency Department

Kung

Chen

et al. 2018

BioMed Research International

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Background Several comorbidities contribute to an increased risk of infections in Parkinson's disease (PD) as the disease progresses. However, few studies have examined the correlation between sepsis and PD. Aim The aim of this study is to disclose the presentation and outcome of serious infection in patients with PD in the emergency department. Methods This retrospective cohort study enrolled patients with PD who had serious infection and were admitted to the emergency department between January 2007 and December 2013. For clinical comparison, we compared the clinical features, laboratory data, and outcomes with those of age- and sex-matched patients who had serious infection but not PD. Results There were a total of 1,200 episodes of infected PD patients and 2,400 age- and sex-matched infected patients without PD as disease controls. PD patients had fewer comorbidities and lower severity of infectious disease but longer hospital stays than control group patients. The incidences of respiratory tract and urinary tract infections were higher in PD patients. The levels of inflammatory and organ dysfunction biomarkers in PD were lower and compatible with the severity of infectious disease. A total of 86 (7.2%) infected PD patients died during the 28-day admission compared to 339 (14.1%) in non-PD patients. Serum C-reactive protein, bandemia, and lactate could be used to predict mortality in infected PD patients. Conclusions In infected patients with PD, respiratory and urinary tract infections were the two most common infectious sources. Empiric therapy based on experience could treat both respiratory and urinary tract infections. Early diagnosis and treatment are essential for survival.

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Section: Discussionsupporting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Manifestations and Outcomes of Patients with Parkinson’s Disease and Serious Infection in the Emergency Department

Kung

Chen

et al. 2018

BioMed Research International

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“…The full text articles of 65 studies were then assessed for eligibility, and of these 56 articles were excluded with reasons. Twenty-three [11,16,17,20,[23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] of the 56 excluded articles reported reasons for admission among people with PD but did not report exact number of people admitted for the reasons they reported so were excluded. (supplementary material: table 2) Finally, data were captured from a total of nine articles: [14,18,19,[42][43][44][45][46][47].…”

Section: Selection Processesmentioning

confidence: 99%

Factors associated with hospitalisation among people with Parkinson's disease – A systematic review and meta-analysis

Okunoye

Kojima

Marston

et al. 2020

Parkinsonism & Related Disorders

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“…Just a "statistical" reminder: aspiration pneumonia is a major cause of morbidity and mortality in almost all neurologic diseases and a major cause of frequent hospital readmissions. 3,4 As a result, it would not be unreasonable to advocate this operation primarily as a dysphagia-improving surgery and secondarily as a voice-improving one! Petros Karkos, MD, PhD, MPhil Department of Otolaryngology, AHEPA University Hospital Agios Loukas Private Clinic Thessaloniki, Greece…”

mentioning

confidence: 99%

“…Just a “statistical” reminder: aspiration pneumonia is a major cause of morbidity and mortality in almost all neurologic diseases and a major cause of frequent hospital readmissions. 3,4…”

mentioning

confidence: 99%

Effects on Swallowing When Treating Unilateral Vocal Fold Palsy

Karkos¹

2016

Otolaryngol.--head neck surg.

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Letters to the Editor 543 centric environment, which makes us look at what patients prefer. My experience has been that when patients are given the choice of avoiding an inpatient hospital stay, they will choose to go home the same day if that is a safe option.Economics are a factor not just for hospitals and health plans but also for our patients who have higher copays.The education of residents should not be determined by the venue in which surgery is being performed but, rather, by the needs of residents to get good training as deemed by the Accreditation Council for Graduate Medical Education (ACGME) Otolaryngology Subsection. Issues concerning residency training should be brought to the Review Committee. Many of our head and neck procedures are already done on an outpatient basis, and this is the new reality that training programs should consider.

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Epidemiology of inpatient stay in Parkinson’s disease in the United States: Insights from the Nationwide Inpatient Sample

Cited by 34 publications

References 9 publications

Manifestations and Outcomes of Patients with Parkinson’s Disease and Serious Infection in the Emergency Department

Manifestations and Outcomes of Patients with Parkinson’s Disease and Serious Infection in the Emergency Department

Factors associated with hospitalisation among people with Parkinson's disease – A systematic review and meta-analysis

Effects on Swallowing When Treating Unilateral Vocal Fold Palsy

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