Abstract:sage:The Indian disease pattern is going through a phase of epidemiological transition with a surge in the incidence of IBD. The epidemiology and disease characteristics of IBD mirror the patterns observed in the West.
“…This is the first such report from Asia, especially when this region is experiencing a rise in disease burden of IBD 6. Diet is an important component of the management plan of any disease and in case of IBD there are many perspectives to diet as perceived by both patient and the physician: as a triggering agent for IBD, as a part of therapeutic strategy, and as a component of nutritional plan.…”
Section: Discussionmentioning
confidence: 98%
“…Diet is also perceived by many patients as an important trigger for relapse and many patients do modify their diet with various phases of disease activity which may compromise their nutritional status. There has been a steady rise in the prevalence of IBD in India and other Asian countries and as per a recent report, the projected disease burden of IBD in India is second highest in the world after USA 5, 6…”
Background and AimPatients with inflammatory bowel disease (IBD) are at a risk of nutritional deficits because of poor dietary beliefs and practices. There are no data on this aspect from Asia, which is experiencing a rise in IBD incidence. We aimed to establish dietary beliefs and practices in patients of IBD from India.MethodsPatients with ulcerative colitis (UC) and Crohn's disease (CD) followed up between November 2016 and March 2017 were included. A questionnaire extracted information on the patients' sociodemographic, nutritional and disease profile, smoking and drinking habits, dietary beliefs and practices, current dietary preferences, intake and avoidance, dietary changes made after diagnosis of IBD, dietary changes made during relapse, frequency of consumption of major food groups, and the attitudes toward dietary advice.ResultsA total of 316 patients (218 UC and 98 CD; mean age: 38.5 ± 12.2 years) were included. Forty‐four percent patients perceived food as a risk factor for IBD, 52% felt dietary habits to have a more important role than medicines in disease control, 77% reported certain foods improve symptoms during relapse, 86% had modified their diet since the diagnosis of IBD (UC > CD, P = 0.04), 90% imposed food restrictions, and <50% had received dietary counseling. About 40% of patients could not meet their dietary requirements and 66% had decreased their dietary intake since diagnosis, which further decreased during relapse (85%).ConclusionDietary beliefs and practices play a central role in perception of disease in IBD patients. A large majority of them make dietary changes which can lead to undernutrition. Proper dietary counseling is required in these patients to prevent malnutrition.
“…This is the first such report from Asia, especially when this region is experiencing a rise in disease burden of IBD 6. Diet is an important component of the management plan of any disease and in case of IBD there are many perspectives to diet as perceived by both patient and the physician: as a triggering agent for IBD, as a part of therapeutic strategy, and as a component of nutritional plan.…”
Section: Discussionmentioning
confidence: 98%
“…Diet is also perceived by many patients as an important trigger for relapse and many patients do modify their diet with various phases of disease activity which may compromise their nutritional status. There has been a steady rise in the prevalence of IBD in India and other Asian countries and as per a recent report, the projected disease burden of IBD in India is second highest in the world after USA 5, 6…”
Background and AimPatients with inflammatory bowel disease (IBD) are at a risk of nutritional deficits because of poor dietary beliefs and practices. There are no data on this aspect from Asia, which is experiencing a rise in IBD incidence. We aimed to establish dietary beliefs and practices in patients of IBD from India.MethodsPatients with ulcerative colitis (UC) and Crohn's disease (CD) followed up between November 2016 and March 2017 were included. A questionnaire extracted information on the patients' sociodemographic, nutritional and disease profile, smoking and drinking habits, dietary beliefs and practices, current dietary preferences, intake and avoidance, dietary changes made after diagnosis of IBD, dietary changes made during relapse, frequency of consumption of major food groups, and the attitudes toward dietary advice.ResultsA total of 316 patients (218 UC and 98 CD; mean age: 38.5 ± 12.2 years) were included. Forty‐four percent patients perceived food as a risk factor for IBD, 52% felt dietary habits to have a more important role than medicines in disease control, 77% reported certain foods improve symptoms during relapse, 86% had modified their diet since the diagnosis of IBD (UC > CD, P = 0.04), 90% imposed food restrictions, and <50% had received dietary counseling. About 40% of patients could not meet their dietary requirements and 66% had decreased their dietary intake since diagnosis, which further decreased during relapse (85%).ConclusionDietary beliefs and practices play a central role in perception of disease in IBD patients. A large majority of them make dietary changes which can lead to undernutrition. Proper dietary counseling is required in these patients to prevent malnutrition.
“…Yang [1] highlights a number of differences in Korean patients compared to their Western counterparts, including the greater prevalence of CD in males, the Western countries acquire the risk of the baseline population [4] . In general, current data, including those presented by Yang [1] and Kedia and Ahuja [2] , do suggest a close similarity between patients diagnosed with IBD in Asia and those diagnosed in the Western world, with few notable differences. A final answer might take a long time to come.…”
mentioning
confidence: 69%
“…IBD natural history, response to biologic therapy, and disease evolution over time appear similar to those reported in the West. By contrast, in their article, Kedia and Ahuja [2] stress some of the striking similarities between IBD in India and IBD in the Western world, including microbial and (mostly) genetic profiles, disease location, disease phenotype, and incidence of colorectal cancer. Interestingly, most studies [3] , including the authors' own, do not confirm the well-known deleterious effect of smoking on CD development and natural history in Asia.…”
mentioning
confidence: 96%
“…In the present issue of the journal, Yang [1] and Kedia and Ahuja [2] revisit this subject in light of recent acquisitions in the field and their own outstanding contributions. Yang [1] highlights a number of differences in Korean patients compared to their Western counterparts, including the greater prevalence of CD in males, the Western countries acquire the risk of the baseline population [4] .…”
Inflammatory bowel disease (IBD) is a continual ailment condition which engrosses the entire alimentary canal. The IBD can be primarily distinguished into two forms, ulcerative colitis, and Crohn's disease. The major symptoms of IBD include pustules or abscesses, severe abdominal pain, diarrhea, fistula, and stenosis, which may directly affect the patient's quality of life. A variety of mediators can stimulate the circumstances of IBD, some examples include infections by microbes such as bacteria, perturbation of the immune system and the surrounding environment of the intestines. Severe colitis was stimulated in the experimental animals through administering 4% dextran sulfate sodium (DSS) which is mixed in water ad libitum for 6 days. Eriocitrin (30 mg/kg) was then administered to the experimental animals followed by the induction of severe colitis to evaluate the therapeutic prospective of eriocitrin against the colon inflammation stimulated by DSS. In this study, eriocitrin (30 mg/kg) demonstrated significant (P < .05) attenuation activity against the DSS-stimulated severe colitis in experimental animals. Eriocitrin counteracted all of the clinical deleterious effects induced by DSS, such as body-weight loss, colon shortening, histopathological injury, accretion of infiltrated inflammatory cells at the inflamed region and the secretion of inflammatory cytokines. The results clearly showed that eriocitrin effectively attenuated DSS-induced acute colitis in experimental animals. K E Y W O R D S colitis, colon and ulceration, dextran sulfate sodium, eriocitrin, inflammation
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