Epidemiology of <i>Staphylococcus aureus</i> in Pigs and Farmers in the Largest Farm in Dakar, Senegal

Fall, Cheikh; Seck, Abdoulaye; Richard, Vincent; Ndour, Moustapha; Sembène, Mbacké; Laurent, François; Breurec, Sébastien

doi:10.1089/fpd.2012.1197

Cited by 52 publications

(77 citation statements)

References 9 publications

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“…CC88 is a widespread human lineage from which MRSA strains evolved that are common in Australia [145] and Sub-Saharan Africa [119,146,147,148,149]. It has been described from laboratory mice [35], from retail food [143] and from pigs [150]. …”

Section: Resultsmentioning

confidence: 99%

Diversity of Staphylococcus aureus Isolates in European Wildlife

et al. 2016

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Staphylococcus aureus is a well-known colonizer and cause of infection among animals and it has been described from numerous domestic and wild animal species. The aim of the present study was to investigate the molecular epidemiology of S. aureus in a convenience sample of European wildlife and to review what previously has been observed in the subject field. 124 S. aureus isolates were collected from wildlife in Germany, Austria and Sweden; they were characterized by DNA microarray hybridization and, for isolates with novel hybridization patterns, by multilocus sequence typing (MLST). The isolates were assigned to 29 clonal complexes and singleton sequence types (CC1, CC5, CC6, CC7, CC8, CC9, CC12, CC15, CC22, CC25, CC30, CC49, CC59, CC88, CC97, CC130, CC133, CC398, ST425, CC599, CC692, CC707, ST890, CC1956, ST2425, CC2671, ST2691, CC2767 and ST2963), some of which (ST2425, ST2691, ST2963) were not described previously. Resistance rates in wildlife strains were rather low and mecA-MRSA isolates were rare (n = 6). mecC-MRSA (n = 8) were identified from a fox, a fallow deer, hares and hedgehogs. The common cattle-associated lineages CC479 and CC705 were not detected in wildlife in the present study while, in contrast, a third common cattle lineage, CC97, was found to be common among cervids. No Staphylococcus argenteus or Staphylococcus schweitzeri-like isolates were found. Systematic studies are required to monitor the possible transmission of human- and livestock-associated S. aureus/MRSA to wildlife and vice versa as well as the possible transmission, by unprotected contact to animals. The prevalence of S. aureus/MRSA in wildlife as well as its population structures in different wildlife host species warrants further investigation.

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Section: Resultsmentioning

confidence: 99%

Diversity of Staphylococcus aureus Isolates in European Wildlife

et al. 2016

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“…First, this similarity, despite different study designs and considerable temporospatial separation of the study populations, suggests that these lineages may be widely distributed among commercial swine populations. However, data from a study of a single farm in Senegal, 7 and observations on wild boar in Spain, 25 indicate that these MSLT lineages are not universal among swine populations. Second, while ST398 is the predominant lineage of livestock-associated MRSA in Europe, 13 ST9 has been predominant in most Asian countries studied, 33 and ST5 MRSA has been commonly isolated from pigs in North America.…”

Section: Discussionmentioning

confidence: 98%

The effect of anatomic site and age on detection of Staphylococcus aureus in pigs

et al. 2014

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Abstract. Despite active research into methicillin-resistant Staphylococcus aureus (MRSA) in pigs since 2004, the ecology of the susceptible ancestral organism has been neglected. A longitudinal study of pigs in 2 intensive production systems was conducted to investigate the effects of age and anatomical site on detection of S. aureus. Sampling was replicated in 2 cohorts per farm, with swabs collected from the nares, tonsils, skin (axilla), and rectum in lactating sows, suckling, weaned, and market-age pigs, plus the vagina of sows. No MRSA were isolated, but S. aureus was detected in a least 1 site in 175 (91.1%) out of 192 pigs. Pig-level prevalence did not differ among the age groups, but the proportion of positive samples (all sites) was higher in market-age pigs (75.2%) and nursery-age pigs (63.2%) than in sows (40.7%) and suckling piglets (38%). Prevalence did not differ among nasal (67.9%), skin (62.3%), and tonsil (61.7%) swabs, but was lower in rectal (42%) and vaginal swabs (39.6%). Multiple multilocus sequence typing (MLST) and spa types were found in both production systems, but all isolates were of ST398, ST9, or ST5. These MLST lineages have been variably predominant among reports of MRSA in pigs on 3 continents, and the presence of methicillin-sensitive variants in several countries raises the likelihood that MRSA in pigs has likely resulted from independent acquisition of the mecA gene by multiple S. aureus lineages that have been adapted to swine over the long term, rather than recent introduction of novel clones into swine populations.

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“…Although few studies have been performed on the epidemiology of LA-MRSA in Africa [18,[149][150][151][152], several lineages have been detected, such as the humanassociated ST5-SCCmec IV and ST88-SCCmec IV in pigs from Senegal [151] and ST153-SCCmec NT from healthy sheep in Tunisia [152]. Moreover, one veterinarian from Tunisia carried an ST80-SCCmec IVc isolate [153], but interestingly, human-associated S. aureus lineages have been described in chimpanzees, possibly as the result of humanosis [18].…”

Section: La-mrsa In Other Parts Of the Worldmentioning

confidence: 99%

Livestock-Associated MRSA and Its Current Evolution

Butaye

Argudín

Smith

2016

Curr Clin Micro Rpt

116

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Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a relatively recent phenomenon in veterinary medicine. Although in the beginning it was restricted to a single clonal complex (CC), CC398, it has expanded into several clonal complexes, and the diversity of subtypes in the clonal complexes is increasing also. The prevalence of each type is determined somewhat geographically; for instance, the most prevalent clonal complex in Europe is CC398, whereas in Asia, it is CC9. Although few data exist regarding North America, the situation appears to be mixed there. The SCCmec cassettes detected in LA-MRSA are limited mainly to SCCmec IVa and SCCmec V, although non-typeable cassettes and SCCmec type XI, containing mecC, also have been found.The source of the SCCmec in LA-MRSA was discovered to be animals. In searching from which bacteria the SCCmec cassettes in LA-MRSA have been transferred, the most obvious species to consider are the methicillin-resistant non-S. aureus staphylococci (MRNaS). However, very few data are available from those species in animals, and the data that do exist are not detailed enough to determine the origin. Nevertheless, similar cassettes were found in MRNaS, indicating a possible origin that needs to be investigated further.

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Epidemiology of Staphylococcus aureus in Pigs and Farmers in the Largest Farm in Dakar, Senegal

Cited by 52 publications

References 9 publications

Diversity of Staphylococcus aureus Isolates in European Wildlife

Diversity of Staphylococcus aureus Isolates in European Wildlife

The effect of anatomic site and age on detection of Staphylococcus aureus in pigs

Livestock-Associated MRSA and Its Current Evolution

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