Epidemiology of Hypertension in Asia

Sy, Rody G.; Llanes, Elmer Jasper B.; Punzalan, Felix Eduardo R.; Aherrera, Jaime Alfonso M.; Cheng, Paula Victoria Catherine Y.

doi:10.1007/978-3-030-95734-6_1

Cited by 4 publications

(3 citation statements)

References 91 publications

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“…Hypertension is one of the leading causes of cardiovascular diseases (CVDs) and premature death worldwide and is the most common risk factor for myocardial infarction, stroke, heart failure, atrial fibrillation, and peripheral arterial disease. , The global prevalence of hypertension has risen dramatically over the past two decades, with an estimated 1.13 billion people living with hypertension today, and this number is expected to reach 1.5 billion by 2025 . The prevention and treatment of hypertension have become a problem of increasing concern.…”

mentioning

confidence: 99%

Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Rice (Oryza sativa L.) Bran Protein

Zhang

Miao

Guo

et al. 2023

J. Agric. Food Chem.

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To realize the high-value utilization of rice byproducts, the rice bran protein hydrolysate was separated and purified by ultrafiltration and reversed-phase high-performance liquid chromatography (RP-HPLC), then the sequences of peptides were identified by liquid chromatography with tandem mass spectrometry (LC–MS/MS), and their molecular docking analysis and activities in vitro and in the cell were carried out. Two novel peptides FDGSPVGY (840.3654 Da) and VFDGVLRPGQ (1086.582 Da) were obtained with IC50 values of 0.079 mg/mL (94.05 μM) and 0.093 mg/mL (85.59 μM) on angiotensin I-converting enzyme (ACE) inhibitory activity in vitro, respectively. Molecular docking results showed that two peptides interacted with ACE receptor protein through hydrogen bonding, hydrophobic interactions, etc. Through the EA.hy926 cells, it was found that FDGSPVGY and VFDGVLRPGQ could promote the release of nitric oxide (NO) and reduce the content of ET-1 to achieve the effect of antihypertension. In conclusion, the peptides from rice bran protein exhibited significant antihypertension activity and may be expected to realize the high-value utilization of rice byproducts.

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mentioning

confidence: 99%

Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Rice (Oryza sativa L.) Bran Protein

Zhang

Miao

Guo

et al. 2023

J. Agric. Food Chem.

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“…Overall, the study evaluated the incidence of hypertension, diabetes, and asthma in the Iraqi population and showed a relatively higher incidence of hypertension and diabetes, along with a lower incidence of asthma, compared to several countries. The study compared the incidence of these diseases in Iraq with that of the United Kingdom [ 15 - 18 ], the United States [ 19 , 20 ], Saudi Arabia [ 21 - 23 ], and Egypt [ 24 - 26 ]. Each country was selected based on a specific criterion to enable meaningful comparisons.…”

Section: Discussionmentioning

confidence: 99%

Stress as a possible cause of a high incidence of hypertension and diabetes and a low incidence of asthma in the Iraqi population

et al. 2023

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Hypertension and diabetes represent a significant public health burden worldwide and are significant risk factors for heart disease and stroke. Nevertheless, Iraqi people, in particular, experience higher levels of stress due to political instability and economic issues. The study aimed to investigate the prevalence of common morbidities among Iraqi patients and the possible relationship with exposure to stress. The data was collected from patients (n=500) who attended the health center in Najaf, Iraq, between 25 August 2021 and 30 September 2021. The prevalence of hypertension, diabetes, and asthma among Iraqi people was determined along with patients’ awareness and control of these conditions. In addition, patients were asked about their experiences with stress, including the type of stress they encountered. Our findings revealed that nearly 47% of patients involved in this study had hypertension, with the highest percentage in patients over 40. Moreover, the incidence of diabetes was 12%, with the highest incidence in the age group of 40-59. The incidence of asthma was lower in all groups. Data analysis concerning exposure to stress demonstrated that about 60% of patients suffer from a stressful life. We found that the incidence of hypertension and diabetes was high while the incidence of asthma was low. This study also reveals that a considerable number of people were unaware of their hypertension and diabetes. Exposure to daily life stress among Iraqi people may play a role in the observed incidence of these morbidities.

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“…The fact that 41 million people could die from NCDs by 2025, primarily due to preventable conditions such as CVD (48%), cancer (21%), and diabetes (3%), highlights the urgent need for effective prevention strategies worldwide [ 3 ]. With an estimated 1.13 billion individuals worldwide having hypertension and staggering two-thirds residing in LMICs, this condition poses a major public health challenge [ 4 ]. The increase in hypertension (HTN) in LMICs compared to its stability or decrease in developed nations is a concerning and well-documented trend in global health research [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Systematic review and meta-analysis on the prevalence and associated factors of depression among hypertensive patients in Ethiopia

Tassew,

Nigate,

Assefa

et al. 2024

PLoS ONE

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Background Identifying individuals at increased risk for depression allows for earlier intervention and treatment, ultimately leading to better outcomes and potentially preventing severe symptoms. However, to date, no systematic reviews or meta-analyses have estimated the prevalence of depression among hypertensive patients. Thus, this review was initiated to determine the prevalence and factors associated with depression among patients with hypertension in Ethiopia. Methods Multiple databases, such as PubMed, African Journals Online, the Cochrane Library, and Google Scholar, were used to ensure wider coverage of relevant studies. The data extracted from Microsoft Excel were imported into STATA version 11 (Stata Corp LLC, TX, USA) for further analysis. The pooled prevalence of depression was estimated using a random effects model. To evaluate statistical heterogeneity, the Cochrane Q test and I2 statistic were used. Results The random effect model indicated that the pooled prevalence of depression in 12 studies conducted in Ethiopia was 32.43% (95% CI: 25.18, 39.67%). Being female (POR = 2.41; 95% CI: 1.89, 3.07, I2 = 17.7%, P = 0.302), having comorbid illnesses (POR = 3.80; 95% CI: 2.09, 6.90, I2 = 81%, P = 0.005), having poor blood pressure control (POR = 3.58; 95% CI: 2.51, 5.12, I2 = 0.0%, P = 0.716), having a family history of depression (POR = 3.43; 95% CI: 1.98, 5.96, I2 = 62.6%, P = 0.069), being single (POR = 2.30; 95% CI: 1.35, 3.99, I2 = 48.0%, P = 0.146) and having poor social support (POR = 4.24; 95% CI: 1.29, 13.98, I2 = 95.8%, P<0.001) were positively associated with depression among hypertensive patients. Conclusion Overall, the results of our review showed that depression affects a significant number of Ethiopians who have hypertension. Being female, being single, having comorbidities, having poor blood pressure control, having a family history of depression, and having poor social support were factors associated with depression among patients with hypertension. For those who are depressed, improving the psycho-behavioral treatment linkage with the psychiatric unit can result in improved clinical outcomes. Trial registration Prospero Registration number: CRD42024498447. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024498447.

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Epidemiology of Hypertension in Asia

Cited by 4 publications

References 91 publications

Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Rice (Oryza sativa L.) Bran Protein

Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Rice (Oryza sativa L.) Bran Protein

Stress as a possible cause of a high incidence of hypertension and diabetes and a low incidence of asthma in the Iraqi population

Systematic review and meta-analysis on the prevalence and associated factors of depression among hypertensive patients in Ethiopia

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