Epidemiology of Gestational Trophoblastic Disease at a Tertiary Hospital in India over Last 8 Years

Jyoti, Ramesh Chandran; D, Sumangala Devi; Gorhatti, Sarah N

doi:10.5005/jp-journals-10006-1645

Journal of South Asian Federation of Obstetrics and Gynaecology

2019

DOI: 10.5005/jp-journals-10006-1645

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Epidemiology of Gestational Trophoblastic Disease at a Tertiary Hospital in India over Last 8 Years

Ramesh Chandran Jyoti¹,

Sumangala Devi D²,

Sarah N Gorhatti³

Abstract: The incidence of gestational trophoblastic disease (GTD) varies all around the world, highest being in Asian countries. This study provides a hospital-based incidence of GTD in a tertiary institution.

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2023

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Successful management of vascular invasive mole by uterine artery embolization and hysterectomy - A case report

Devalla¹,

Kalra²,

Kumar³

et al. 2023

IJOGR

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Gestational Trophoblastic Neoplasia (GTN) is a rare disease originating from pregnancy events that have varied incidences and clinical manifestations based on regional variation. We are reporting a case of a 36-year-old woman with Invasive mole from Central India who presented with abnormal uterine bleeding with severe anemia. She had three full-term vaginal deliveries and 2 spontaneous abortions, the last conception being an abortion around 7 years back. MRI pelvis demonstrated a hypervascular uterine mass suggestive of an Invasive Mole, supported by increased serum β-hCG levels of 31.8 IU/ml. There was no evidence of any metastases on adjunct radiological investigations. After a thorough counselling, the enlarged vascular uterine mass was managed by uterine artery embolization (UAE) followed by simple hysterectomy. Histopathology report confirmed the diagnosis of invasive mole with villi lying in the fibrinous blood clot sheath of the syncytial, and cytotrophoblasts were seen invading the myometrium foci. The patient being in the low risk FIGO scoring, calculated was 5, chemotherapy was not deemed necessary for the patient. Serial post operative β-hCG along with ultrasound pelvis and chest radiogram surveillance showed favourable results with no evidence of metastases even on 6 months follow up. Being a very rare condition, a high index of suspicion with prompt timely management ensures optimum care.

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Successful management of vascular invasive mole by uterine artery embolization and hysterectomy - A case report

Devalla¹,

Kalra²,

Kumar³

et al. 2023

IJOGR

View full text Add to dashboard Cite

show abstract

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Epidemiology of Gestational Trophoblastic Disease at a Tertiary Hospital in India over Last 8 Years

Abstract: The incidence of gestational trophoblastic disease (GTD) varies all around the world, highest being in Asian countries. This study provides a hospital-based incidence of GTD in a tertiary institution.

Cited by 1 publication

References 3 publications

Successful management of vascular invasive mole by uterine artery embolization and hysterectomy - A case report

Successful management of vascular invasive mole by uterine artery embolization and hysterectomy - A case report

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