Epidemiology of gastroesophageal reflux disease in Tehran, Iran

Ehsani, Mohammad Javad; Maleki, Iradj; Mohammadzadeh, Fatemeh; Mashayekh, Ameneh

doi:10.1111/j.1440-1746.2006.04616.x

Cited by 18 publications

(23 citation statements)

References 28 publications

(44 reference statements)

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“…In our study, 635 subjects (28%) suffered from GERD, which was more prevalent in women. Our finding was similar to some studies reported around the country(16); Tehran (21.2% and 39.7%), 17,18 Mashhad, 19 Firoozkooh and Damavand (29.2%), 20 and Tabriz (26.8%). 21 It was higher compared with some other studies, ie.…”

Section: Discussionsupporting

confidence: 92%

Review of Clinical Spectrum of Gastroesophageal Reflux Disease in a General Population; A Study from South-East Iran

Darvishmoghadam

Zahedi

Abbasi

et al. 2016

Middle East J Dig Dis

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BACKGROUNDGastroesophageal reflux disease (GERD) is one of the most common gastrointestinal problems worldwide. The aim of this study was to evaluate the clinical spectrum, prevalence, and some of the variables that are supposed to be the risk factors of this chronic disorder.METHODSThis population- based cross-sectional study was conducted in a one-stage randomized clustered sample of adult inhabitants in Kerman city in 2011-2012. A total of 2265 subjects with age range of 15-85 years were enrolled. Face to face interview was performed for all the subjects. GERD was defined as at least weekly heart burn and/or acid regurgitation during the past year. Association of GERD with factors like demographic variables, medical condition, diet and life habits were analyzed.RESULTS A total of 2265 subjects including 988 (43.8%) male and 1275 (56.3%) female patients were evaluated. The prevalence of GERD was 28%. The prevalence was higher in female patients and with aging. There was also a significant association between GERD and the following risk factors: lower educational level (p <0.0001), higher body mass index (p =003), presence of depression(p<0.0001), and anxiety (p <0=0001). CONCLUSIONGERD as a common disorder in our region was seen more in elderly and female patients and was associated with some anthropometric, metabolic, medical conditions, and behavioral habits.

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Section: Discussionsupporting

confidence: 92%

Review of Clinical Spectrum of Gastroesophageal Reflux Disease in a General Population; A Study from South-East Iran

Darvishmoghadam

Zahedi

Abbasi

et al. 2016

Middle East J Dig Dis

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“…Similarly, a sedentary type of living was shown to poorly correlate with reflux disease (19, 26). Similar to previous literature, cigarette smoking was considered as a risk factor for reflux in our study (16, 19, 26). In contrast, tea consumption (17, 19, 26, 36) n addition to fast food (36) have been introduced as common risk factors for GERD.…”

Section: Discussionsupporting

confidence: 74%

“…There is a significant correlation between a depressed sense of well-being and the severity of GERD (14, 15). In Iran, significantly different prevalence rates for GERD have been reported by different studies, reflecting the varying methodologies and definitions implemented (16-20). Body mass index (BMI) is a risk factor for GERD, yet weight loss does not improve the disease.…”

Section: Introductionmentioning

confidence: 99%

An Epidemiological Study of Gastroesophageal Reflux Disease and Related Risk Factors in Urban Population of Mashhad, Iran

Vossoughinia¹,

Salari²,

Amirmajdi³

et al. 2014

Iran Red Crescent Med J

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Background:Gastroesophageal Reflux Disease (GERD) is a chronic and common disease, which is characterized by heartburn and regurgitation. In the last couple of decades, GERD has received much attention and studies have shown an increase in its prevalence. Although there have been a few studies on the prevalence of GERD in Iran, no study has yet been done in the northeastern part of the country. The aim of our study was to evaluate the prevalence of GERD and its risk factors in a population from Mashhad.Objectives:To evaluate the epidemiology of GERD based on a population study in Mashhad.Patients and Methods:This was a cross sectional descriptive study conducted in 2010. In total, 2500 participants were selected based on cluster sampling. Modified and validated Mayo Clinic questionnaire for GERD was used for data collection. Overall, 1685 questionnaires were retrieved. Fifty-one participants were excluded because of pregnancies, history of abdominal surgery and being less than 18 years old. We analyzed data using the SPSS software version 16. Prevalence of GERD and significant risk factors (P value < 0.05) were determined.Results:In total, 420 participants (25.7%) had GERD symptoms. Risk factors with significant effects consisted of smoking, consumption of non-steroidal anti-inflammatory drugs (NASIDs), overeating, chronic diseases, tea and coffee consumption and GERD in spouse.Conclusions:The prevalence of GERD among people living in Mashhad was above the average prevalence in other cities of Iran. However, risk factors seemed to be similar to those reported by other studies.

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“…In Asia, the reported prevalence of GERD varies, but generally is about 2.3-6.2% [6]. In Iran, the prevalence of GERD and dyspepsia is about 8.3 and 7.7%, respectively [7,8,9,10,11,12]. It has been shown that upper GI disorders have negative effects on health-related quality of life, are associated with great costs for the patient and society, and can increase the risk of esophageal cancer [13,14,15,16].…”

Section: Introductionmentioning

confidence: 99%

Smoking Status and Prevalence of Upper Gastrointestinal Disorders

Esmaillzadeh¹,

Keshteli

Tabesh³

et al. 2014

Digestion

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Background: Lifestyle and environmental factors affecting upper gastrointestinal (GI) disorders are different in developing countries than those in developed nations. Objective: This study aimed to examine the association between smoking status and upper GI disorders among a large group of the Iranian adult population. Methods: This cross-sectional study was conducted among 1,933 adult men in Isfahan, Iran. Smoking status was assessed by a self-administered questionnaire. Required information on GI health was collected through the use of the validated ROME III questionnaire. Individuals who reported having heartburn sometimes, often, or always in the last 3 months were considered as having epidemiologic gastroesophageal reflux disease (GERD), and those who reported having heartburn often or always were considered as having clinical GERD. Subjects who reported having functional dyspepsia (FD) symptoms (based on the ROME III criteria) sometimes, often, or always in the last 3 months were considered as having epidemiologic FD, and those who reported having these disorders often or always were considered as having clinical FD. Results: Smoking was prevalent among 7.8% of the study population. FD and GERD was prevalent among 12.6% (n = 244) and 22.3% (n = 432), respectively. Smoking was not associated with GERD by either the epidemiologic or clinical definition. Although the association between smoking and FD (epidemiologic definition) was not statistically significant, smokers had an 83% higher risk of suffering from clinical FD compared with nonsmokers after taking potential confounders into account [odds ratio (OR) = 1.83, 95% CI: 1.12-3.00; p = 0.01]. Smokers had a 57% higher risk for epidemiologic postprandial fullness (OR = 1.57, 95% CI: 1.05-2.33; p = 0.02) and a 92% higher risk for clinical epigastric pain compared with nonsmokers (OR = 1.92, 95% CI: 1.02-3.62; p = 0.04). We found no significant association between smoking and severity of upper GI disorders. Conclusion: This large population-based study indicated that smoking was not associated with GERD and epidemiologic FD. However, smoking was significantly associated with clinical FD, postprandial fullness, and epigastric pain.

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Epidemiology of gastroesophageal reflux disease in Tehran, Iran

Cited by 18 publications

References 28 publications

Review of Clinical Spectrum of Gastroesophageal Reflux Disease in a General Population; A Study from South-East Iran

Review of Clinical Spectrum of Gastroesophageal Reflux Disease in a General Population; A Study from South-East Iran

An Epidemiological Study of Gastroesophageal Reflux Disease and Related Risk Factors in Urban Population of Mashhad, Iran

Smoking Status and Prevalence of Upper Gastrointestinal Disorders

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