Epidemiology of gastroesophageal reflux disease in Iran: a systematic review and meta-analysis

Karimian, Mohammad; Nourmohammadi, Hassan; Salamati, Majid; Ahmadi, Mohammad Reza; Kazemi, Fatemeh; Azami, Milad

doi:10.1186/s12876-020-01417-6

Cited by 18 publications

(20 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…43 A systematic review and meta-analysis study in Iranian population the daily, weekly, monthly, and overall prevalence of GERD symptoms was 5.64%, 12.50%, 18.62% and 43.07%, respectively. 44 The present meta-analysis has many strengths. We utilized a universal and repeated search to increase the ability to detect all related papers.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Dyspepsia in Iran: A Systematic Review and Meta-analysis

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background: Dyspepsia is a highly prevalent gastrointestinal problem. The present study was carried out to assess the prevalence of dyspepsia in Iran. Methods: The present study was registered at PROSPERO with the code CRD42019148610. It was carried out based on MOOSE and reporting was performed according to the PRISMA protocol. Systematic search of the literature was performed in July 2019 on international databases of PubMed/Medline, Web of Science (ISI), Cochrane Library, EBSCO, CINAHL, EMBASE, Scopus, Science Direct, and local databases as well as the Google Scholar search engine. Heterogeneity was evaluated using I 2 and Chi-square tests. All analyses were done using Comprehensive Meta-Analysis software. Results: Overall, 14 studies with a sample size of 54,118 subjects entered in this meta-analysis. The prevalence of dyspepsia in Iran was 14.6% (95% CI: 9.6-21.7). Large heterogeneity was detected among studies (I 2 = 99.62%, P < 0.001). The prevalence of dysmotility-like, ulcer-like, and unspecified dyspepsia was estimated to be 9.7% (95% CI: 4.9-18.4), 12.1% (95% CI: 5.2-25.7) and 17.0% (95% CI: 7.8-33.4), respectively. The prevalence of dyspepsia in Iranian men and women was found at 11.1% (95%

show abstract

Section: Discussionmentioning

confidence: 99%

Prevalence of Dyspepsia in Iran: A Systematic Review and Meta-analysis

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…GERD is known as another important risk factor for esophageal cancer which is associated with obesity as well [9]. A systematic review and meta-analysis conducted in Iran have shown that the overall prevalence of GERD in the Iranian population was about 40%, so it is an important risk factor to take into account [20]. Also, it was shown that the daily symptoms of GERD were significantly higher in females [20].…”

Section: Discussionmentioning

confidence: 99%

“…A systematic review and meta-analysis conducted in Iran have shown that the overall prevalence of GERD in the Iranian population was about 40%, so it is an important risk factor to take into account [20]. Also, it was shown that the daily symptoms of GERD were significantly higher in females [20]. Furthermore, obesity and smoking were known as possible risk factors for developing Barret's esophagus in GERD [21].…”

Section: Discussionmentioning

confidence: 99%

Investigating Trends of Incidence Rates of Esophageal Cancer Divided by Squamous Cell Carcinoma and Adenocarcinoma in Southern Iran: a 10-Year Experience

Hosseini-Bensenjan

Vardanjani

Haghpanah

et al. 2021

J Gastrointest Canc

View full text Add to dashboard Cite

Background Gastrointestinal cancers account for a significant number of deaths and new cancer cases worldwide. Our aim is to investigate stratum-specific incidence trends of EC in southern Iran considering age, gender, and morphological (adenocarcinoma/squamous cell carcinoma) subtypes. Method We used data on esophageal cancer incidence in the catchment area of Shiraz Population-Based Cancer Registry. New cancer cases with ICD-O-3 codes of C15.0 to C15.9 were retrieved and prepared. New annual cases were counted for categories defied based on age group, gender, and morphology. Average annual percentage change (AAPC) and its 95% CI was estimated for each trend using joinpoint regression. ResultsThe total number of esophageal cancer was higher in males than females. It is an increasing rate in esophageal adenocarcinoma in females and this increase was more prominent in older ages. Also, our study showed that SCC has a decreasing trend in females and a steady trend in males. Discussion Taken together, the increasing trend in adenocarcinoma in females in our study can be related to the increasing rate of obesity and smoking in females in recent years in our region. The incidence trend of different morphologic types of esophageal cancer is changing. This can be a consequence of alterations in the incidence trend of different risk factors. It is necessary to conduct more studies evaluating these risk factors.

show abstract

“…Gastroesophageal Re ux Disease (GERD) is a common gastrointestinal disorder that adversely affects the patients' quality of life (1)(2)(3). Considering wide use of over-the-counter medications and diagnostic procedures, it imposes a huge economic burden on the healthcare system (4).…”

Section: Introductionmentioning

confidence: 99%

The relationship between white tongue and gastroesophageal reflux disease

Jamali

Goodarzi

Jamali

et al. 2022

Preprint

View full text Add to dashboard Cite

Background Signs of gastroesophageal reflux disease (GERD) are limited, therefore, follow up of treatment are mainly based on patients’ symptoms. The aims of study were: 1) to compare the prevalence of white tongue (WT) between individuals with GERD and control group, 2) to evaluate the correlation between WT extension and severity of symptoms in GERD. Materials and methods This case-control study consisted of 100 consecutive individuals with GERD who were referred to the gastroenterology clinic of a referral hospital during 2019-2020. The diagnosis of GERD was made by a gastroenterologist if heart burn or regurgitation existed. The same number of healthy accompanies of patients without GERD participated as the control group. A single examiner defined WT if whitish-gray discoloration of tongue surface existed in two separate sessions [Kappa = 0.93; p < 0.01]. WT extension was estimated based on the approximate white discoloration of the tongue surface. Results All participants with GERD showed white tongue in the first observation and 98% in the second observation, while only 5% of the individuals in the control group revealed WT in both observations (p < 0.001). There was a positive correlation between the WT extension and GERD symptom severity (r: 0.44; p < 0.001). Conclusion It seems that WT might be a reliable sign of GERD. Considering the association between GERD symptoms severity and the extent of WT in this observation, further studies may assess the utility of WT extension as a reasonable objective in monitoring treatment response.

show abstract

Epidemiology of gastroesophageal reflux disease in Iran: a systematic review and meta-analysis

Cited by 18 publications

References 46 publications

Prevalence of Dyspepsia in Iran: A Systematic Review and Meta-analysis

Prevalence of Dyspepsia in Iran: A Systematic Review and Meta-analysis

Investigating Trends of Incidence Rates of Esophageal Cancer Divided by Squamous Cell Carcinoma and Adenocarcinoma in Southern Iran: a 10-Year Experience

The relationship between white tongue and gastroesophageal reflux disease

Contact Info

Product

Resources

About