Epidemiology of Chronic Kidney Disease and Associated Metabolic Risk Factors in an Old Chinese Population

Abstract

Chronic kidney disease (CKD) has become a worldwide health problem among aging populations. However, epidemiological information on Chinese elderly people with CKD is still lacking. This study aimed to investigate the epidemiological features and associated risk factors of CKD in aging population in China. In this cross-sectional study, a total of 37,533 individuals aged ≥65 years were enrolled in Binhai from January to December 2018. The crude and standardized prevalence of CKD were calculated. Associations of metabolism-related indicators with CKD were examined using univariate and multivariate analysis. The overall prevalence of CKD was 17.7% (95% confidence interval [CI], 17.3%-18.1%) in this Chinese elderly population. The prevalence was 17.5% among men (95% CI, 17.0%-18.1%) and 17.8% among women (95% CI, 17.3 -18.4%). The mean eGFR was 84.22 (SD ± 12.87) mL/min/1.73 m2, with the median value higher for women than for men. Aging, pre-HTN, HTN, elevated triglyceride and FBG were found to be independent risk factors for CKD. Our study shows a high prevalence of CKD among Chinese elderly population. Aging, pre-HTN, HTN, elevated triglyceride and FBG were all independent risk factors associated with CKD. More attention should be paid to metabolic diseases to prevent CKD in the elderly.