Epidemiology of catheter-related infections in adult patients receiving home parenteral nutrition: A systematic review

Dreesen, Mira; Foulon, Veerle; Spriet, Isabel; Goossens, Godelieve; Hiele, Martin; Pourcq, Lutgart De; Willems, Ludo

doi:10.1016/j.clnu.2012.08.004

Cited by 152 publications

(133 citation statements)

References 49 publications

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“…We identified CRBSI by positive blood culture in a symptomatic child with fever and/or signs of sepsis. 7,10 Blood culture was taken when body temperature was recorded as more than 38.5 C on at least one occasion or the child had other symptoms such as temperature instability, unusual lethargy or any new, otherwise inexplicable symptom that in the individual patient had been associated with a previous episode of septicaemia. CRBSIs were treated with intravenous antibiotics according to our local microbiology protocol.…”

Section: Methodsmentioning

confidence: 99%

“…6 Repeated CVC change can lead to occlusion of access sites. 7,8 Hence, every effort should be directed to safeguard the longevity of CVCs as the risk of accumulated complications and the loss of vascular access can have direct life-threatening consequences. 5 The principle of aseptic non-touch technique (ANTT) is based on the fact that if a key part is not touched, it cannot be contaminated.…”

Section: Introductionmentioning

confidence: 99%

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Aseptic non‐touch technique and catheter‐related bloodstream infection in children receiving parenteral nutrition at home

et al. 2015

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Objectives: Parenteral nutrition (PN) at home is an acceptable form of delivering long-term PN for children with intestinal failure. Catheter-related bloodstream infection (CRBSI) is one of the serious complications of long-term PN and can lead to increasing morbidity and mortality. Using aseptic non-touch technique (ANTT) was proven to decrease the incidence of CRBSI in hospital patients. In this study we aimed to review the incidence of CRBSI in children receiving PN at home in our institution using the ANTT and a simplified training programme for parents and carers. Methods: We retrospectively collected clinical and microbiological data on all children with intestinal failure (IF) who were on treatment with PN at home under our specialist IF rehabilitation service between November 2012 and November 2013. Results: Thirty-five children were included, 16 of whom did not have any infection recorded during the study period. The overall CRBSI rate was 1.3 infections per 1000 line-days, with Staphylococcus being the commonest organism. Twenty-one children did not require catheter change and the overall catheter changes were 1.8 per 1000 line-days. Conclusion: In this article, we report a low incidence of CRBSI in a single institution by using the principle of ANTT for accessing central venous catheters combined with a simplified, nurse-led, two-week standardised training programme for parents of children going home on PN.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Aseptic non‐touch technique and catheter‐related bloodstream infection in children receiving parenteral nutrition at home

et al. 2015

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“…The infection rate is highly variable and depends on the patient's clinical conditions and the antiseptic techniques used by the administrators. The CRBSI rate has been reported to be 0.38-4.58/1,000 days (12)(13)(14). Four of the present seven cases experienced CRBSI.…”

Section: Discussionmentioning

confidence: 76%

Home Parenteral Nutrition Therapy in Seven Patients with Anorexia Nervosa: The Role and Indications

Hotta

Araki

Urano³

et al. 2014

Intern. Med.

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Home parenteral nutrition (HPN) is a well-established intervention to sustain life in malnourished patients at home. Because it is difficult for patients with anorexia nervosa (AN) to gain weight or stop purging, such patients require repeated hospitalizations. Although HPN has not been commonly used for AN patients in Japan, we utilized this approach to treat seven AN patients. We herein present the clinical course and outcome of these seven patients, the application criteria for HPN in our institution, and the potential problems associated with HPN. Despite its complications, HPN may be a useful measure to help patients with persistent AN avoid multiple hospitalizations.

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“…This corresponds with the results of previous studies: 28.6% had at least one catheter sepsis and 50% had at least one catheter change. CVC infection rate ranged between 0.38 and 4.58 episodes per 1,000 catheter days [19,20] . To prevent infections and other catheter-related complications, good clinical practice and an experienced multidisciplinary team are mandatory [21] .…”

Section: Discussionmentioning

confidence: 99%

Management of Home Parenteral Nutrition: A Prospective Multicenter Observational Study

et al. 2015

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BACKGROUND: There are no specific Swiss home parenteral nutrition (HPN) data showing patient characteristics, quality of life (QoL) and complications. The goal of this study was to collect representative nationwide data on current adult HPN patients in Switzerland for international comparability and benchmarking. METHODS: This was a multicenter, nationwide, observational study. We conducted interviews for demographics, PN characteristics, QoL and complications. The data were assessed at baseline and after a follow-up of 3 months using a questionnaire. RESULTS: Thirty-three adult patients were included. The most common underlying diseases were cancer, radiation enteritis and state after bariatric surgery, and the most prevalent indication was short bowel syndrome. During the 3-month observation period, significant increase or stabilization of body weight occurred in the patients, physical activity scores improved from 34.0 to 39.4 and mental scores improved from 41.9 to 46.4. HPN dependency and traveling restrictions were of the greatest concern. Diarrhea, xerostomia and/or thirst were frequent complaints. CONCLUSION: Anthropometric parameters and QoL improved during the observational period in this HPN cohort. These Swiss HPN data are prerequisite for evaluation and comparison of HPN recommendations and best clinical practice, status of professional care instructions related to HPN effectiveness, quality of treatment and patient safety.

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Epidemiology of catheter-related infections in adult patients receiving home parenteral nutrition: A systematic review

Cited by 152 publications

References 49 publications

Aseptic non‐touch technique and catheter‐related bloodstream infection in children receiving parenteral nutrition at home

Aseptic non‐touch technique and catheter‐related bloodstream infection in children receiving parenteral nutrition at home

Home Parenteral Nutrition Therapy in Seven Patients with Anorexia Nervosa: The Role and Indications

Management of Home Parenteral Nutrition: A Prospective Multicenter Observational Study

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