Epidemiology of cardiovascular diseases related admissions in a referral hospital in the South West region of Cameroon: A cross-sectional study in sub-Saharan Africa

Nkoké, Clovis; Jingi, Ahmadou Musa; Makoge, Christelle; Teuwafeu, Denis; Nkouonlack, Cyrille; Dzudie, Anastase

doi:10.1371/journal.pone.0226644

Cited by 14 publications

(14 citation statements)

References 23 publications

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“…More females than males were hospitalized for CVDs within the study period. Similar observation was reported by Adedapo 15 , Oguanobi et al 40 , Njoku et al 14 , Nwafor et al 29 and Nkoke et al 16 in Ibadan, Enugu, Keffi, Portharcourt and Southwest Cameroun respectively but contradicts those of some other researchers from within Nigeria 26,28 . This could be because the present study spanned over 10 years with more participants than the other studies which were for a period of 2-3 years with fewer study populations.…”

Section: Discussionsupporting

confidence: 79%

“…In a hospital based study in Keffi 14 , Northcentral Nigeria, CVDs were the predominant NCDs causing hospitalization followed by diabetes mellitus (DM) related complications at 37.7% and 23.7% respectively. In another hospital based study in South-western Nigeria 15 , CVDs accounted for 37.0% of all medical admissions with an overall mortality of 17% while in a hospital based study in Southwest Cameroun 16 , CVDs accounted for 15.9% of medical admissions with 15.8% in-hospital case fatality. In a Pakistan 17 cross sectional study, the pattern of NCDs noted were systemic hypertension, ischemic heart diseases and DM at 38.7%, 34.4% and 14.6% respectively with identified risk factors being tobacco use (48.2%), drug abuse (13.6%) and alcohol consumption (1.8%).…”

Section: Introductionmentioning

confidence: 94%

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Emerging Trends in the Burden of Cardiovascular Diseases in the Southeast Region of Nigeria

Nkpozi

Adukwu

Ezeude

et al. 2020

J. Drug Delivery Ther.

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Background and Objective: Cardiovascular diseases (CVDs) are leading causes of non-communicable diseases and are increasingly becoming the major causes of morbidity and mortality in Nigeria. Published literature on the changing patterns and outcome of CVD admissions in the southeast region of Nigeria is scanty. This study, therefore, set out to bridge this gap in knowledge. Subjects and Methods: This was a 10-year retrospective descriptive study in which data about patients admitted on account of the CVDs to the medical wards of Abia State University Teaching Hospital (ABSUTH), Aba from May 1, 2007 to April 30, 2017 were extracted from the Admission/Discharge registers in the medical wards. Relevant data obtained were analyzed using Statistical Package for Social Sciences (SPSS) version 23.0 software. Results: A total of 2044 patients were admitted because of CVDs, made up of 927 (45.4%) males and 1117 (54.6%) females. Cerebrovascular disease (stroke), heart failure (HF) and uncontrolled systemic hypertension (SHTN) were the major cardiovascular indications for hospitalization at 44.08%, 38.85% and 15.31% respectively. With an overall CVD mortality of 24.9% of the medical admissions, the commonest cause of CVD deaths was stroke. Majority of the CVD deaths (70.9%) occurred within the first 7 days of hospitalization Conclusion: Contribution of cardiovascular diseases to medical admissions is considerable in Aba, Southeast Nigeria. In-patient mortality of the CVDs is high especially from stroke. It is recommended that every effort should be made to control the modifiable risk factors of CVDs while early detection and treatment of CVDs be effected. Keywords: Aba, cardiovascular diseases, medical wards, non-communicable diseases, Southeast, Nigeria

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Section: Discussionsupporting

confidence: 79%

Section: Introductionmentioning

confidence: 94%

Emerging Trends in the Burden of Cardiovascular Diseases in the Southeast Region of Nigeria

Nkpozi

Adukwu

Ezeude

et al. 2020

J. Drug Delivery Ther.

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“…Cardiovascular disease (CVD) is a leading cause of death and in sub Saharan Africa; women are more likely to die of heart disease compared to the men. [1,2] Overall, incidence of heart disease and other non-communicable diseases is on the on the rise in resource limited settings. [3] Prior history of pre-eclampsia or eclampsia increases cardiovascular risk later in life.…”

Section: Introductionmentioning

confidence: 99%

Perceptions on preeclampsia and eclampsia among older women in rural southwestern Uganda

Nabulo

Ruzaaza

Mugabi

et al. 2020

Preprint

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Background Eclampsia is among the leading causes of maternal mortality. It is a serious hypertensive (HT) complication of pregnancy and increases the risk of cardiovascular disease (CVD) in later life. Pregnancy-related HT complications predispose to chronic hypertension and premature heart attacks. A significant proportion of women with preeclampsia/eclampsia does not reach the formal healthcare system or arrive too late because of certain African cultural beliefs about the condition. The older senior women in the community play a significant role in decision making regarding where mothers should maternal health care. Therefore, the purpose of this study was to explore the perceptions of older women regarding the manifestation of, risk factors and possible causes of preeclampsia/eclampsia. Methods We conducted a qualitative study in a rural area in southwestern Uganda. The key informants were older women including community elders, village health team members and traditional birth attendants who were believed to hold local knowledge and influence on birth and delivery. We purposively selected key informants (KI) and data were collected till we reached saturation point. We analyzed data using a combined inductive and deductive approach to identify themes. Analysis was completed using N-Vivo version 12. Results We interviewed 20 key informants. Four themes emerged namely: traditional local naming, causes and risk factors, remedies, and effects of preeclampsia/eclampsia. There was no identifiable local name from the interviews. Women carried several myths regarding the cause and these included little blood, witchcraft, stress from marital tension and ghost attacks. The remedies identified included herbal treatment, prayers and corrective nutrition. Women were generally aware of the outcomes of eclampsia. Conclusion Eclampsia is associated with significant myths and misconceptions in this rural community. We recommend interventions to increase awareness and dispel the myths and misconceptions regarding eclampsia in the community.

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“…More than 80% of CDV deaths occur in low and middle-income countries, affecting men and women at the same rates [4]. A recent study carried out in Cameroon showed that deaths related to CDV (in-hospital case-fatality) were 15.8% [5].…”

Section: Introductionmentioning

confidence: 99%

Screening and molecular characterization of cholesterol-lowering lactic acid bacteria isolated from African oil palm wine (Elaeis guineensis) and corn beer.

Fossi¹,

Ekabe²,

Toukam³

et al. 2020

Preprint

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Background: High serum cholesterol is a risk factor for cardiovascular disease (CVD), leading to many fatalities. Probiotic supplementation improves health benefits by lowering serum cholesterol. African oil palm (Elaeis guineensis) wine and corn beer have been described as potential sources of probiotic bacteria, but their cholesterol lowering activity has not been extensively investigated. Therefore in this study, we isolated and characterized lactic acid bacteria with probiotic and cholesterol lowering properties from these sources.Methods: A total of fifty lactic acid bacteria (LAB) were isolated from palm wine and corn beer using de Man Rogosa and Sharpe (MRS) agar by pour plate method. Catalase negative and Gram positive colonies were considered as presumptive LAB. For probiotic properties and selection, acid and bile salt tolerance were evaluated based on viable colony count on MRS agar and cholesterol assimilation from culture media was performed by spectrophotometry. The data analysis was performed by One Way Analysis of Variance and p value< 0.05 was considered significant. The isolates with excellent cholesterol assimilation properties were selected and identified with species of morphology and biochemical analysis using API 50 CHL kit and genotypic identification by sequencing of 16 S rRNA gene.Results: Fifty isolates had morphological features similar to LAB. They were catalase negative and Gram positive colonies. Among the fifty isolates, five were considered as acid and bile tolerant (viable count exceeded 6logCFU/ml), with two isolates having excellent cholesterol assimilation property (>80%). The result obtained using API 50 CHL kit did not agree with the genotypic identification which was used to confirm the identity of the isolates as most closely related to Lactobacillus brevis ATCC (Accession No.NR116238) and Enterococcus faeccium NBRC (Accession No. NR113904).Conclusions: The two strains isolated from traditionally fermented drinks in Buea can be considered as potential probiotics. They can therefore be used to formulate food supplement needed to lower cholesterol in hypercholesterolemia patients.

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Epidemiology of cardiovascular diseases related admissions in a referral hospital in the South West region of Cameroon: A cross-sectional study in sub-Saharan Africa

Cited by 14 publications

References 23 publications

Emerging Trends in the Burden of Cardiovascular Diseases in the Southeast Region of Nigeria

Emerging Trends in the Burden of Cardiovascular Diseases in the Southeast Region of Nigeria

Perceptions on preeclampsia and eclampsia among older women in rural southwestern Uganda

Screening and molecular characterization of cholesterol-lowering lactic acid bacteria isolated from African oil palm wine (Elaeis guineensis) and corn beer.

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