Epidemiology of cancer of the prostate

Abstract

This study of the epidemiology of cancer of the prostate was based on a retrospective investigation of 300 patients with cancer of the prostate and 400 controls, a review of the charts of an additional 350 patient with prostate cancer, and a review of the literature. The main etiologic lead to which this study could not contribute is the rarity of clinical prostatic cancer in Japan and its increase among Japanese immigrants in the U.S. However, the low rate among Jewish males in the U.S. seems to be related to a lower rate of prostatic cancer among immigrants from Eastern Europe. U.S. Negroes have a higher incidence rate than Caucasians. No significant relationship was found to socioeconomic status, marital status, fertility, social habits, previous diseases, weight, height, hair distribution, or laboratory data.

Descriptive epidemiology of testicular and prostatic cancer in Los Angeles

“…It seems unlikely that these differences have an entirely genetic basis, since in African blacks this disease is reportedly much less common (Wynder et al, 1971 ; HIigginson & Oettle, 1960). In Rhodesian blacks, for example, cancer rates for all sites combined are higher than for American blacks, but rates for cancer of the prostate are less than half the American rates (Doll et al, 1970).…”

“…Studies of male genital cancer, particularly of the testis and prostate, have been less frequent, despite the fact that testicular cancer rates have substantially increased in recent years (Clemmesen, 1968;Petersen & Lee, 1972) and that in the United States the prostate is already the second commonest site of cancer in the male (Cutler & Young, 1975). Prostatic cancer rates have also been reported to be rising in various populations (Wynder et al, 1971;Krain, 1973). In fact, age-adjusted prostatic cancer rates for black males in Los Angeles County are higher than the rates for any other site for either sex or any racial-ethnic group.…”

Diabetes Mellitus Reduces Prostate Cancer Risk - No Function of Age at Diagnosis or Duration of Disease

“…Later in 2006, another meta-analysis containing 19 studies (Wynder et al, 1971;Ragozzino et al, 1982;Mishina et al, 1985;Thompson et al, 1989;Smith et al, 1992;Steenland et al, 1995;Coughlin et al, 1996;Will et al, 1999;Rosenberg et al, 2002;Tavani et al, 2002;Weiderpass et al, 2002;Coker et al, 2004;Lightfoot et al, 2004;Zhu et al, 2004;Gonzalez-Perez et al, 2005;Rodriguez et al, 2005;Tavani et al, 2005) was published (Kasper et al, 2006). They both showed that diabetic patients have a statistically significant (9% in 2004 and 16% in 2006) decrease in the risk of developing PCa.…”

“…The first meta-analysis including 14 studies (Wynder et al, 1971;Ragozzino et al, 1982;Checkoway et al,…”

A cohort study of mortality from cancer of the prostate in Catholic priests

“…Evidence for and against the first two hypotheses has been presented extensively elsewhere (Wynder et al, 1971; Ross et al, 1979). Support for the third theory comes from a number of epidemiological findings.…”