Epidemiology of cancer from the oral cavity and oropharynx

Lambert, René; Sauvaget, Catherine; Cancela, Marianna de Camargo; Sankaranarayanan, Rengaswamy

doi:10.1097/meg.0b013e3283484795

Cited by 212 publications

(157 citation statements)

References 61 publications

Supporting

Mentioning

134

Contrasting

Unclassified

Order By: Relevance

“…A large number of studies have confirmed the roles of tobacco smoking, alcohol drinking and betel quid chewing in aetiology (Lambert et al, 2011). Infection with Human papillomavirus (HPV) has also been shown to be a major risk factor for oral cancer in recent studies (Kreimer et al, 2005).…”

Section: Introductionmentioning

confidence: 92%

Risk Factors for Oral Cancer in Northeast Thailand

Loyha

Vatanasapt

Promthet³

et al. 2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Oral cancer is a common site of head and neck cancer, and is relatively frequent in Northeast Thailand. The objective of this hospital-based, case-control study was to determine associations with risk factors. A total of 104 oral cancer cases diagnosed between July 2010 and April 2011 in 3 hospitals were matched with control subjects by age, sex and hospital. Data were collected by personal interview. There were significant associations between oral cancer and tobacco smoking (OR=4.47; 95%CI=2.00 to 9.99), alcohol use among women (OR=4.16; 95%CI=1.70 to 10.69), and betel chewing (OR=9.01; 95%CI=3.83 to 21.22), and all three showed dose-response effects. Smoking is rare among Thai women (none of the control women were smokers), but betel chewing, especially among older women, is relatively common. We did not find any association between practicing oral sex and oral cancer.

show abstract

Section: Introductionmentioning

confidence: 92%

Risk Factors for Oral Cancer in Northeast Thailand

Loyha

Vatanasapt

Promthet³

et al. 2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…The incidence rate in males exceeds 20 per 100,000 in regions of Hong Kong, the Indian subcontinent, parts of Europe and among African Americans in the United States [3]. In Europe, there were approximately 250,000 cases and 63,500 deaths in 2012 [4].…”

Section: Introductionmentioning

confidence: 99%

Bone Marrow Failure in HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Ka¹,

Newbold²,

Thway³

et al. 2018

JOENTR

View full text Add to dashboard Cite

A 56-year-old gentleman presented with bleeding from his mouth and gums. He also had a left neck lump and throat discomfort. He was found to have a p16+ oropharyngeal squamous cell carcinoma (OPSCC) of his left tonsil with ipsilateral level II and III nodal involvement. A PET scan revealed extremely diffuse metastatic disease involving all vertebral bodies, both humeri, femora and scapulae, pelvis, skull and other sites. He was anaemic and profoundly thrombocytopaenic as a result of his bony metastatic disease.During the course of his disease his pain was difficult to control and he received regular packed red cells and platelets to support his failing bone marrow. A high suspicion of, and thorough investigation for, a second malignancy provided no answers. He received 2 cycles of dose-adjusted Paclitaxel chemotherapy but sadly did not respond to this and died 10 weeks following presentation due to bone marrow failure. Keywords:

show abstract

“…Oral squamous cell carcinoma (OSCC) is the most common oral and maxillofacial malignancy (Lambert et al 2011). Currently, the morbidity and mortality rates of OSCC are still high in most countries.…”

Section: Introductionmentioning

confidence: 99%

Non-Invasive Techniques for Detection and Diagnosis of Oral Potentially Malignant Disorders

Liu

Zhao

Zeng

et al. 2016

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

Oral squamous cell carcinoma (OSCC) is the most common oral and maxillofacial malignancy, and its morbidity and mortality rates are still high in most countries. Oral potentially malignant disorders (PMDs) are used to refer to a heterogeneous group of conditions that are characterized by increased risk for malignant transformation to OSCC. Currently identified oral PMDs include leukoplakia, erythroplakia, palatal lesions associated with reverse smoking, oral lichen planus, oral submucous fibrosis, actinic keratosis, and discoid lupus erythematosus. The early detection and diagnosis of these lesions are important for cancer prevention and disease management. In recent years, there has been a growing and persistent demand for new non-invasive, practical diagnostic techniques that might facilitate the early detection of oral PMDs. The non-invasive detection techniques evaluated in this review are divided into four categories: vital staining with a solution that can be used as a mouth rinse or applied onto a suspected area of the mouth, light-based detection systems, optical diagnostic technologies that employ returned optical signals to reflect structural and morphological changes within tissues, and salivary biomarkers. Most of these techniques have shown great potential for screening and monitoring oral PMDs. In this review article, the authors critically assess these non-invasive detection techniques for oral PMDs. We also provide a summary of the sensitivity and specificity of each technique in detecting oral PMDs and oral cancer, as well as their advantages, disadvantages, clinical applications, and indications.

show abstract

Epidemiology of cancer from the oral cavity and oropharynx

Cited by 212 publications

References 61 publications

Risk Factors for Oral Cancer in Northeast Thailand

Risk Factors for Oral Cancer in Northeast Thailand

Bone Marrow Failure in HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Non-Invasive Techniques for Detection and Diagnosis of Oral Potentially Malignant Disorders

Contact Info

Product

Resources

About