Epidemiology of Bowel Endometriosis

Ferrero, Simone; Barra, Fabio; Altieri, Michele; Orsi, Andrea; Icardi, Giancarlo; Noberasco, Giovanni

doi:10.1007/978-3-030-50446-5_2

Cited by 3 publications

(3 citation statements)

References 83 publications

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“…However, this subpopulation is less represented in our study as the Endotest® was developed in women aged between 18 and 43 years. Moreover, MRI and ultrasound are highly effective for diagnosing endometriosis with colorectal involvement, 7 observed in 5%–12% of patients with deep endometriosis, 42 possibly rendering the Endotest® less cost‐effective in this setting. However, for patients with other and more common locations of deep endometriosis – mainly the torus uterinum, uterosacral ligament and vagina – the Endotest® could be relevant, as there is poor accuracy in the diagnostic imaging for these sites.…”

Section: Discussionmentioning

confidence: 99%

Saliva microRNA signature to diagnose endometriosis: A cost‐effectiveness evaluation of the Endotest®

Ferrier

Bendifallah

Suisse³

et al. 2022

BJOG

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To evaluate a saliva diagnostic test (Endotest®) for endometriosis compared with the conventional algorithm. Design: A cost-effectiveness analysis with a decision-tree model based on literature data. Setting: France. Population: Women with chronic pelvic pain. Methods: Strategy I is the French algorithm, representing the comparator. For strategy II, all patients have an Endotest®. For strategy III, patients undergo ultrasonography to detect endometrioma and patients with no endometrioma detected have an Endotest®. For strategy IV, patients with no endometrioma detected on ultrasonography undergo pelvic magnetic resonance imaging (MRI) to detect endometrioma and/or deep endometriosis. An Endotest® is then performed for patients with a negative result on MRI. Main outcomes measures: Costs and accuracy rates and incremental costeffectiveness ratios (ICERs). Three analyses were performed with an Endotest® priced at €500, €750, and €1000. Probabilistic sensitivity analysis was conducted with Monte Carlo simulations. Results: With an Endotest® priced at €750, the cost per correctly diagnosed case was €1542, €990, €919 and €1000, respectively, for strategies I, II, III and IV. Strategy I was dominated by all other strategies. Strategies IV, III and II were, respectively, preferred for a willingness-to-pay threshold below €473, between €473 and €4670, and beyond €4670 per correctly diagnosed case. At a price of €500 per Endotest®, strategy I was dominated by all other strategies. At €1000, the ICERs of strategies II and III were €724 and €387 per correctly diagnosed case, respectively, compared with strategy I. Conclusion:The present study demonstrates the value of the Endotest® from an economic perspective.

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Section: Discussionmentioning

confidence: 99%

Saliva microRNA signature to diagnose endometriosis: A cost‐effectiveness evaluation of the Endotest®

Ferrier

Bendifallah

Suisse³

et al. 2022

BJOG

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“…Although there is wide heterogeneity on the prevalence of AppE, it is estimated to be present in 15% of women with bowel endometriosis [1,2,11]. When the appendix is affected, endometriosis generally involves the appendiceal body in 56% of cases and the tip in 44%.…”

Section: Appendiceal Endometriosismentioning

confidence: 99%

“…The base of the appendix is not typically affected. Of the four distinct histological layers within the appendix (mucosa, submucosa, muscularis propria and serosa), the muscularis is affected in two-thirds of cases and the serosa in one-third of cases [11][12][13][14].…”

Section: Appendiceal Endometriosismentioning

confidence: 99%

Appendectomy in endometriosis: an update on surgical indications and management of uncommon diseases

Galaviz

Nguyen

Sticco

et al. 2023

Current Opinion in Obstetrics &Amp; Gynecology

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Purpose of reviewAbnormal appendiceal disease is commonly encountered following an appendectomy when performed in patients with endometriosis. Appendiceal endometriosis is the most notable finding and can affect up to 39% of patients with endometriosis. Despite this knowledge, guidelines for performing an appendectomy have not been formally established. In this article, we review the surgical indications for an appendectomy at the time of endometriosis surgery and discuss the management of other diseases that may be encountered following the histopathologic evaluation of an excised appendix.Recent findingsRemoval of the appendix in patients with endometriosis contributes to optimal surgical management. Relying on abnormal appendiceal appearance for removal may leave endometriosis-affected appendices. For this reason, utilizing risk factors to guide surgical management is essential. Common appendiceal diseases are sufficiently managed with appendectomy. Uncommon diseases may require further surveillance.SummaryEmerging data in our field support the performance of an appendectomy at the time of endometriosis surgery. Guidelines for performing a concurrent appendectomy should be formalized to encourage preoperative counselling and management for patients with risk factors for appendiceal endometriosis. Abnormal diseases is frequently encountered after appendectomy in the setting of endometriosis surgery and further management is based on the histopathology of the specimen.

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