Epidemiology of ANCA-associated Vasculitis

Ntatsaki, Eleana; Watts, Richard A.; Scott, David G. I.

doi:10.1016/j.rdc.2010.04.002

Cited by 198 publications

(130 citation statements)

References 51 publications

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“…36 Patients with EGPA present with a fairly characteristic constellation of symptoms including asthma, peripheral eosinophilia, neuropathy, and cardiac disease. 37 Asthma may precede other symptoms for years.…”

Section: Microscopic Polyangiitismentioning

confidence: 99%

Pathology of Antineutrophil Cytoplasmic Antibody–Associated Pulmonary and Renal Disease

Smith¹

2017

Archives of Pathology &Amp; Laboratory Medicine

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Context.—Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis commonly presents with pulmonary and renal involvement that may present diagnostic challenges. Objectives.—To highlight the updates in the classification of small vessel vasculitis, present the patterns of pulmonary and renal pathology in which ANCA-associated vasculitis is included in the differential diagnosis, analyze the screening and specific antineutrophil cytoplasmic antibody testing methods in the clinical laboratory, compare and contrast the 3 major ANCA-associated vasculitis diseases, and review the pathophysiologic mechanisms of tissue injury in this setting. Data Sources.—Data are derived from published literature and clinical experience. Conclusions.—Although rare, ANCA-associated vasculitis diseases are often considered in the differential diagnosis of many pathologic patterns of pulmonary and renal disease. Histopathologic diagnosis of specific entities in this context nearly always requires correlation of the pathology with clinical and serologic data.

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Section: Microscopic Polyangiitismentioning

confidence: 99%

Pathology of Antineutrophil Cytoplasmic Antibody–Associated Pulmonary and Renal Disease

Smith¹

2017

Archives of Pathology &Amp; Laboratory Medicine

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“…Its etiopathogenesis is not known but environmental factors such as infection and drug exposure have been studied as potential risk factors. 2 In the present case, a female patient presenting with pyuria, treated initially for urinary infection but diagnosed with ANCA negative vasculitis upon history, physical examination, laboratory and imaging findings was reported. And, she was diagnosed as having immune complex glomerulonephritis by renal biopsy.…”

Section: Introductionmentioning

confidence: 74%

Presentation antineutrophil cytoplasmic autoantibody negative-associated granulomatosis with polyangiitis with pyuria

et al. 2016

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“…The average incidence of AAV in Japan appears to be similar to that in the UK, which have 22.6 and 21.8 cases per million individuals annually, respectively [8]. Collectively, there is believed to be an overall incidence of approximately 10-20 cases per million individuals annually in Caucasian patients of European descent [9]. There are also multiple reports that demonstrate differences in incidence relative to latitude.…”

Section: Anca-associated Vasculitidesmentioning

confidence: 99%