Epidemiology, Diagnosis, and Prevention of Sparganosis in Asia

Liu, W.; Gong, Teng-Fang; Chen, Shuyu; Liu, Quan; Zhou, Haoying; He, Jun-Lin; Yong, Wu; Li, Fen; Zeng, Jianguo

doi:10.3390/ani12121578

Cited by 13 publications

(4 citation statements)

References 63 publications

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“…In the Pantanal, periodic floods and drought distinctly modulate the occurrence of parasites, resulting in defined seasonal infection trends for species such as Spirometra spp. [ 100 , 106 , 109 , 110 , 111 , 112 ]. In contrast, the characteristics of the Cerrado influence the lifecycle of parasites that rely on direct contact with the soil or ingestion of infected prey, including Taenia spp.…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal Helminths in Wild Felids in the Cerrado and Pantanal: Zoonotic Bioindicators in Important Brazilian Biomes

Moraes,

Silva,

Andrade-Silva

et al. 2024

Animals

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Environmental changes in the Brazilian Pantanal and Cerrado facilitate the spread of parasitic diseases in wildlife, with significant implications for public health owing to their zoonotic potential. This study aimed to examine the occurrence and diversity of gastrointestinal parasites in wild felids within these regions to assess their ecological and health impacts. We collected and analyzed helminth-positive samples from 27 wild felids using specific taxonomic keys. Diverse parasitic taxa were detected, including zoonotic helminths, such as Ancylostoma braziliense, Ancylostoma caninum, Ancylostoma pluridentatum, Toxocara cati, Toxocara canis, Dipylidium caninum, Taenia spp., Echinococcus spp., and Spirometra spp. Other nematodes, such as Physaloptera praeputialis and Physaloptera anomala, were identified, along with acanthocephalans from the genus Oncicola and a trematode, Neodiplostomum spp. (potentially the first record of this parasite in wild felids in the Americas). Human encroachment into natural habitats has profound effects on wild populations, influencing parasitic infection rates and patterns. This study underscores the importance of continuous monitoring and research on parasitic infections as a means of safeguarding both wildlife and human populations and highlights the role of wild felids as bioindicators of environmental health.

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Section: Discussionmentioning

confidence: 99%

Gastrointestinal Helminths in Wild Felids in the Cerrado and Pantanal: Zoonotic Bioindicators in Important Brazilian Biomes

Moraes,

Silva,

Andrade-Silva

et al. 2024

Animals

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“…A meta-analysis review estimated the global prevalence of Spirometra in dogs to be 0.0723%, with S. mansoni being the most prevalent species (0.141%) in low-income countries (0.288%) of Africa (0.224%). In the same study, cats presented a higher prevalence (0.1040%), with S. erinaceieuropaei as the most prevalent species (0.268%) in lower-middle income countries (0.134%) of Oceania (0.203%) [ 129 , 132 ].…”

Section: Tapeworms In Prey: Cestode Diseases Associated To Predationmentioning

confidence: 94%

Zoonotic parasites associated with predation by dogs and cats

Roldan

Otranto

2023

Parasites Vectors

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One of the most common behaviors of cats that have an indoor/outdoor lifestyle is to bring hunted “gifts” to their owners, represented by small mammals, reptiles and birds. Access to the outdoors by dogs and cats may represent a problematic issue, since they may be at risk of diseases, traffic accidents and ingestion of toxins. Yet, the impact of this population of roaming dogs and cats predating wildlife is another concerning issue that receives less attention. Despite these risks, most owners still prefer to give outdoor access to their pets to allow them to express their “natural instincts,” such as hunting. Therefore, with a growing population of > 470 million dogs and 373 million cats worldwide, predation not only represents a threat to wildlife, but also a door of transmission for parasitic diseases, some of them of zoonotic concern. In this review, the role played by dogs, and especially cats, in the perpetuation of the biological life cycle of zoonotic parasites through the predation of rodents, reptiles and birds is discussed. Feral and domestics dogs and cats have contributed to the population collapse or extinction of > 63 species of reptiles, mammals and birds. Although the ecological impact of predation on wild populations is well documented, the zoonotic risk of transmission of parasitic diseases has not received significant attention. The parasitic diseases associated to predation vary from protozoan agents, such as toxoplasmosis, to cestodes like sparganosis and even nematodes such as toxocariasis. Raising awareness about predation as a risk of zoonotic parasitic infections in dogs and cats will aid to create responsible ownership and proper actions for controlling feral and free-roaming cat and dog populations worldwide. Graphical Abstract

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“…The plerocercoid (sparganum) of S. mansoni can parasitize humans and animals, causing a food/water-borne parasitic zoonosis known as sparganosis [ 3 ]. The occurrence of human sparganosis has been reported in Asian, African, American and European countries, with more than 2000 cases to date [ 3 – 5 ]. Humans are usually infected by drinking water with infected copepods, consuming raw or uncooked meat infected with plerocercoids (e.g., tadpoles, frogs or snakes) and directly contacting raw meat of secondary hosts used as a poultice through eyes or wounds [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Integrated transcriptomic and proteomic analyses of plerocercoid and adult Spirometra mansoni reveal potential important pathways in the development of the medical tapeworm

Wang,

Li,

Liu

et al. 2023

Parasites Vectors

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Background Spirometra mansoni can parasitize animals and humans through food and water, causing parasitic zoonosis. Knowledge of the developmental process of S. mansoni is crucial for effective treatment; thus, it is important to characterize differential and specific proteins and pathways associated with parasite development. Methods In this study, we performed a comparative proteomic analysis of the plerocercoid and adult stages using a tandem mass tag-based quantitative proteomic approach. Additionally, integrated transcriptomic and proteomic analyses were conducted to obtain the full protein expression profiles of different life cycle stages of the tapeworm. Results Approximately 1166 differentially expressed proteins (DEPs) were identified in adults versus plerocercoids, of which 641 DEPs were upregulated and 525 were downregulated. Gene Ontology (GO), Clusters of Orthologous groups (COG) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses indicated that most DEPs related to genetic information processing and metabolism of energy in adults seem to be more activated. In the plerocercoid stage, compared to metabolism, genetic information processing appears more dynamic. Protein-protein interaction (PPI) revealed six key proteins (phosphomannomutase, glutathione transferase, malate dehydrogenase, cytoplasmic, 40S ribosomal protein S15, ribosomal protein L15 and 60S acidic ribosomal protein P2) that may play active roles in the growth and development of S. mansoni. Finally, the combination of transcriptomic and proteomic data suggested that three pathways (ubiquitin-mediated proteolysis, phagosome and spliceosome) and five proteins closely related to these pathways might have a significant influence in S. mansoni. Conclusions These findings contribute to increasing the knowledge on the protein expression profiles of S. mansoni and provide new insights into functional studies on the molecular mechanisms of the neglected medical tapeworm. Graphical Abstract

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Epidemiology, Diagnosis, and Prevention of Sparganosis in Asia

Cited by 13 publications

References 63 publications

Gastrointestinal Helminths in Wild Felids in the Cerrado and Pantanal: Zoonotic Bioindicators in Important Brazilian Biomes

Gastrointestinal Helminths in Wild Felids in the Cerrado and Pantanal: Zoonotic Bioindicators in Important Brazilian Biomes

Zoonotic parasites associated with predation by dogs and cats

Integrated transcriptomic and proteomic analyses of plerocercoid and adult Spirometra mansoni reveal potential important pathways in the development of the medical tapeworm

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