Epidemiology, Clinical Features, and Prescribing Patterns of Aortic Aneurysm in Asian Population From 2005 to 2011

Abstract

Aortic aneurysm (AA) is a leading cause of death in Asia and the world. The prevalence in Western countries is around 1.3% to 8%. However, it is still unclear about the incidence, prevalence, and mortality of AA in Asian population. The aim of this study is to investigate the epidemiology of AA for all subtypes in Taiwan, and describe the clinical features and prescribing patterns for AA population.A population-based study was conducted using information from National Health Insurance Research Database (NHIRD) in Taiwan. Patients who were diagnosed with AA and also received computed tomography (CT) were included in this study. Incidence, prevalence, and mortality were calculated in each year during 2005 to 2011. Prevalent comorbidities and prescribing patterns were both evaluated among study population.The average annual incidence of AA in Taiwan was 7.35 per 100,000 population, and the prevalence was 29.04 per 100,000 population. It showed an increased trend of incidence from 2005 to 2011, so as prevalence and mortality. The incidence was associated with age and sex difference. It was much higher in those older than 65 years, especially for male. Hypertension, coronary artery disease (CAD), and chronic obstructive pulmonary disease (COPD) were prevalent comorbidities. Eighty-eight percentages of patients were prescribed antihypertensive agents in acute phase, where 61.4% of calcium channel blocker (CCB) was the most one.Our study found that incidence of AA was lower in Taiwan than in other countries. Nevertheless, it showed an increased trend of AA disease for incidence, prevalence, and also mortality during 2005 to 2011.

Association between use of oral-antidiabetic drugs and the risk of aortic aneurysm: a nested case–control analysis

“…Finally, comparing with epidemiological studies in Western countries, our study showed a relatively low prevalence among Taiwanese population, which was consistent with previous studies from Asian countries (0.3–0.5 %) [30]. However, the prevalence and incident rate in Taiwan NHI database were even lower than reported rates among other Asian countries [30]. The prevalence calculated from diagnosis-specific claim data might be lower than those epidemiological data from the reports of screening programs.…”

Increased risk of deep vein thrombosis and pulmonary thromboembolism in patients with aortic aneurysms: A nationwide cohort study

“…Notably, the risk of AA increases dramatically after 60 years of age [ 1 ]. Patients older than or equal to 75 years predominated in our AA cohort (56.4%), and males accounted for most cases (73.3%), which is consistent with prior studies [ 1 , 14 ].…”

Impact of chronic obstructive pulmonary disease on patients with aortic aneurysms: a nationwide retrospective cohort study in Taiwan

“…Data regarding hospital visits, emergency care and prescriptions were provided by the National Health Insurance Research Institutes. The diagnosis of AA in the NHIRD has previously been described 9. This study was approved by the Institutional Review Board of Kaohsiung Medical University Hospital (KMUH-IRB-EXEMPT-20130199).…”

“…The diagnosis of AA in the NHIRD has previously been described. 9 This study was approved by the Institutional Review Board of Kaohsiung Medical University Hospital (KMUH-IRB-EXEMPT-20130199).…”