Epidemiology, Clinical, and Laboratory Characteristics of Bronchiolitis in Hospitalized Children

Soleimani, Gholamreza; Shahri, Elham Shafighi; Rashidi, Somayeh; Salari, Zahra; Moghadam, Alireza Ansari

doi:10.17795/compreped-18808

Cited by 5 publications

(9 citation statements)

References 14 publications

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“…observed apnea in 14% of children. [ 28 29 ] Sahleh et al . found more than half of his patients were having chest wall retractions and in our study also subcostal (83%) and intercostal (70%) retractions were seen in more than half patients.…”

Section: Discussionmentioning

confidence: 99%

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Clinico demographic profiling of the Respiratory syncytial virus (RSV) infected children admitted in tertiary care hospital in North India

Singh

Angurana

Bora

et al. 2021

J Family Med Prim Care

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Background: Acute bronchiolitis is fatal disease involving lower respiratory tract of infants and children of paediatric age group. Respiratory Syncytial Virus (RSV) is responsible for causing more than 70% hospital admissions of children aged less than 2 years thus making a necessity for accurate and timely diagnosis. Aims: The main aim of study was clinicodemographic correlation of RSV positive children presenting to our tertiary care hospital. Setting and Design: It is a retrospective study done between December to January 2018. Materials and Methods: Detection of RSV antigen from nasophyrangeal aspirates using Mouse Monoclonal anti RSV Antibody (by Novatetra) and Goat Anti Mouse Antibody conjugated with FITC as secondary antibody. Results: A total of 147 samples were received in the laboratory and 20 were tested as positive for RSV Antigen. Totally, 19/20 children were aged less than 1 year and with a male predominance. The most common symptom was cough and respiratory distress. Eight percent of the children showed wheezing and 18/20 required assisted ventilation. The clinical course in one child deteriorated leading to death of that patient. Conclusions: The timely diagnosis and management of RSV infected children is utmost needed to prevent morbidity and mortality. The premorbid conditions can assist to differentiate the viral from bacterial pneumonia and thus enable speedy recovery of the child.

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Section: Discussionmentioning

confidence: 99%

“…[ Table 1 ] Crepititions were seen in 15/20 (75%) patients which is similar to findings in a study from Doha in which 73.5% patients had crepts. [ 29 30 31 ]…”

Section: Discussionmentioning

confidence: 99%

Clinico demographic profiling of the Respiratory syncytial virus (RSV) infected children admitted in tertiary care hospital in North India

Singh

Angurana

Bora

et al. 2021

J Family Med Prim Care

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“…Another study conducted in 2016 reported a HBoV prevalence of 1.8% in children with a mean age of 2.1 months [ 27 ]. According to previous studies, the prevalence of HBoV infection is generally higher within the ages of 3 to 6 months [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…Because the lungs and immune system of young children are not fully maturated, acute bronchiolitis can be a serious clinical condition leading to the blockage of airways in these children. Acute bronchiolitis is generally diagnosed based on clinical and chest X-ray (CXR) examinations; however, complete blood cell count (CBC) can also be helpful [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

The prevalence of human bocavirus in <2-year-old children with acute bronchiolitis

Falahi

Sayyadi

Abdoli

et al. 2020

New Microbes and New Infections

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Acute bronchiolitis is one of the most common lower respiratory tract infections in children with less than 2 years of age. Nowadays, molecular methods provide an opportunity to better understand the etiology of bronchiolitis. Several viral agents including Respiratory syncytial virus (RSV), Rhinovirus, Parainfluenza and Human bocavirus (HBoV) are responsible for acute bronchiolitis. There are growing studies on the prevalence of HBoV in patients with bronchiolitis. The present systematic review and meta-analysis were conducted to determine the pooled prevalence of HBoV in the respiratory samples of children with acute bronchiolitis. A literature search was conducted in the databases of PubMed, Scopus and Web of Science to recruit studies reporting the frequency of HBoV in <2-year-old children with acute bronchiolitis from 2005 to 2019. Only studies that used polymerase chain reaction (PCR)-based methods to detect the virus in nasopharyngeal samples were included. A total of 22 studies assessing 6751 cases were analyzed. According to the meta-analysis based on the random-effects model, the overall prevalence of HBoV in children with <2 years old was obtained 13% (95% CI: 0.09-0.17). Additionally, the rates of single (as the sole organism) and mixed (in combination with other viruses) HBoV infections were 4% and 9%, respectively. This study showed a high rate of HBoV detection in children with acute bronchiolitis. This should be considered as part of a diagnostic test panel for respiratory infections in children with bronchiolitis.

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“…Therefore, some studies suggested specific clinical factors for increasing the sensitivity of the diagnosis (12) . Soleimani et al study demonstrated that most of such common clinical signs include cough, wheezing, rhinorrhea, fever, and dyspnea, consecutively among Iranian population (13) . Moreover, radiologic findings including hyperinflation was the most prevalent finding (13) .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Radiographic Findings in Children with Different Severity of Pneumonia Aged from 1 Month to 18 Years Old

2021

IJFMT

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Objectives: to evaluate the relationship between different chest X-ray (CXR) radiologic findings in pediatric patients admitted with different severity of pneumonia. Material and methods: The present descriptiveanalytical cross-sectional study took place in Ali Ibn Abitaleb Hospital (Zahedan, Iran). Every pediatric patient with the clinical diagnosis of pneumonia enrolled and the study population was divided into nonsevere, severe, and very severe groups based on the world health organization criteria of pneumonia severity. The CXR findings of every pediatric patient were reported and the correlation between the radiologic findings and disease severity was evaluated. Results: A total of 352 patients with a mean age of 22.63 months enrolled and the majority of patients were male (212, 60.2%). The intensity of disease was nonsevere in the majority of patients (279, 79.3%) and severe in 17.6%. There was a significant difference between disease severity groups in terms of age (p<0.001) and radiographic findings (p<0.001). There was a significant relationship between severe disease and age (p=0.002, OR=0.964, 95% CI for OR: 0.942, 0.986). Moreover, there was a significant relationship between very severe disease and reticular pattern (p=0.042, OR=9.543, 95% CI for OR: 1.086, 83.886). Conclusion: The present study demonstrated that CXR findings in children with pneumonia are correlated with disease severity and consolidation and reticular patterns are the important findings indicating disease severity in children.

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Epidemiology, Clinical, and Laboratory Characteristics of Bronchiolitis in Hospitalized Children

Cited by 5 publications

References 14 publications

Clinico demographic profiling of the Respiratory syncytial virus (RSV) infected children admitted in tertiary care hospital in North India

Clinico demographic profiling of the Respiratory syncytial virus (RSV) infected children admitted in tertiary care hospital in North India

The prevalence of human bocavirus in <2-year-old children with acute bronchiolitis

Evaluation of Radiographic Findings in Children with Different Severity of Pneumonia Aged from 1 Month to 18 Years Old

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