Epidemiology and the Natural Course of Inflammatory Bowel Disease

Andres, Pietro G.; Friedman, Lawrence S.

doi:10.1016/s0889-8553(05)70056-x

Cited by 261 publications

(196 citation statements)

References 109 publications

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“…Among patients with IUC, 12 (11.7%) needed some type of surgical procedure in the course of the disease, in patients with CD this amount corresponded to 27 (26.2%). As for the site of the disease, among patients with CD, 24 (58.5%) presented ileal/ileocecal, 4 (9.8%) colonic, 7 (17.1%) ileocolonic, 1 (2.4%) upper digest tract and 5 (12.2%) perianal and rectal; these findings match other studies (20,25) . As for the extension of the IUC involvement, we have found the following: 32 (51.6%) patients with proctitis/ proctosigmoiditis, 7 (11.3%) with left-sided colitis and 23 (37.1%) with pancolitis, these findings are compatible with those found by some authors (20) .…”

Section: Remarksupporting

confidence: 89%

Qualidade de vida de pacientes portadores de doença inflamatória intestinal

Souza¹,

Barbosa

Espinosa

et al. 2011

Acta paul. enferm.

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Objectives:To assess the quality of life (QV) in patients with inflammatory bowel disease (DII), and relate it to demographic data and morbidity. Methods: Cross-sectional study with 103 patients with DII, registered in the high cost pharmacy of Cuiabá -Mato Grosso, who responded to the Standard Medical Record, the general QV questionnaire SF-36 and the specific IBDQ. Results: Among 103 patients with DII, 62 had ulcerative colitis and 41 had Crohn's disease; 62% were women; 69.9% were married; 48.5% were of mixed race; 49.5% were smokers; 37.9% required surgery; and, 40.8% had active disease. We observed significant changes in QV in men, smokers and those with active disease. Conclusion: DII affect QV in several respects. Measures for maintenance of QV, psychological, social and education support should be considered for patients with DII. Keywords: Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Colitis; Quality of life RESUMOObjetivos: Avaliar a qualidade de vida (QV) de portadores de doenças inflamatórias intestinais (DII) e relacionar dados sociodemográficos e mórbidos à QV. Métodos: Estudo transversal, realizado com 103 portadores de DII, cadastrados na farmácia de alto custo de Cuiabá -Mato Grosso que responderam ao Prontuário-Padrão, ao questionário de QV geral SF36 e ao específico IBDQ. Resultados: Dentre os 103 pacientes com DII, 62 tinham retocolite ulcerativa idiopática e 41 doença de Crohn; 62% eram mulheres; 69,9%, casados; 48,5%, pardos; 49,5%, fumantes, 37,9% necessitaram de cirurgia e 40,8% apresentavam doença em atividade. Foi observada alteração significativa da QV em homens, fumantes e entre aqueles com doença em atividade. Conclusão: DII afetam a QV em diversos aspectos. Medidas para manutenção da QV, suporte psicológico, social e educacional devem ser considerados para portadores de DII. Descritores: Doença inflamatória intestinal; Doença de Crohn; Retocolite ulcerativa; Colite; Qualidade de vida RESUMEN Objetivos: Evaluar la calidad de vida (CV) de portadores de enfermedades inflamatorias intestinales (EII) y relacionar datos sociodemográficos y mórbidos a la CV. Métodos: Se trata de un estudio transversal, realizado con 103 portadores de EII, registrados en la farmacia de alto costo de Cuiabá -Mato Grosso que respondieron a la Historia Clínica-Patrón, al cuestionario de CV general SF36 y al específico IBDQ. Resultados: De los 103 pacientes con EII, 62 tenían rectocolitis ulcerosa idiopática y 41 enfermedad de Crohn; 62% eran mujeres; 69,9%, casados; 48,5%, pardos; 49,5%, fumadores, 37,9% necesitaron de cirugía y 40,8% presentaban la enfermedad en actividad. Fue observada una alteración significativa de la CV en hombres, fumadores y en aquellos con la enfermedad en actividad. Conclusión: Las EII afectan la CV en diversos aspectos. Para la manutención de la CV, deben ser considerados el soporte psicológico, social y educacional de los portadores de EII. Descriptores: Enfermedad inflamatoria intestinal; Enfermedad de Crohn; Colite ulcerosa; Colite; Calidad de vida

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Section: Remarksupporting

confidence: 89%

Qualidade de vida de pacientes portadores de doença inflamatória intestinal

Souza¹,

Barbosa

Espinosa

et al. 2011

Acta paul. enferm.

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“…While pregnancy has not been shown to specifically increase the risks of IBD "flares" [19] , approximately 30%-40% of women with IBD active at the time of conception will develop more intense disease or endure disease flares during pregnancy [33,34] . Some studies show that disease outcomes and flares in IBD outside of pregnancy are linked to environmental factors and lifestyle including hormone use, diet, mental health status, cigarette smoking, and vitamin D levels [35] .…”

Section: Disease Activity During Pregnancymentioning

confidence: 99%

Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management

Hosseini‐Carroll¹,

Mutyala²,

Seth³

et al. 2015

WJGPT

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Manas K made critical revisions of the manuscript; Becker F and Alexander JS contributed equally as senior authors. Conflict-of-interest statement:There are no known conflicts of interest. The authors (Pegah Hosseini-Carroll, Monica Mutyala, Abhishek Seth, Shaheen Nageeb, Demiana Soliman, Moheb Boktor, Ankur Sheth, Jonathon Chapman, James Morris, Paul Jordan, Kenneth Manas, Felix Becker, and J Steven Alexander) have no relevant financial considerations related to this proposal, and the study was not supported by any corporate entity. There is no known intellectual property associated with this report. AbstractInflammatory bowel diseases (IBD) are chronic idiopathic inflammatory conditions characterized by relapsing and remitting episodes of inflammation which can affect several different regions of the gastrointestinal tract, but also shows extra-intestinal manifestations. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While IBD therapy has improved dramatically with enhanced surveillance and more abundant and powerful treatment options, IBD disease can have important effects on pregnancy and presents several challenges for maintaining optimal outcomes for mothers with IBD and the developing fetus/neonate. Women with IBD, the medical team treating them (both gastroenterologists and obstetricians/gynecologists) must often make highly complicated choices regarding conception, pregnancy, and post-natal care (particularly breastfeeding) related to their choice of treatment options at different phases of pregnancy as well as post-partum. This current review discusses current concerns and recommendations for pregnancy during 157November 6, 2015|Volume 6|Issue 4| WJGPT|www.wjgnet.com Hosseini-Carroll P et al . Pregnancy and inflammatory bowel diseases IBD and is intended for gastroenterologists, general practitioners and IBD patients intending to become, (or already) pregnant, and their families. We have addressed patterns of IBD inheritance, effects of IBD on fertility and conception (in both men and women), the effects of IBD disease activity on maintenance of pregnancy and outcomes, risks of diagnostic procedures during pregnancy and potential risks and complications associated with different classes of IBD therapeutics. We also have evaluated the clinical experience using "top-down" care with biologics, which is currently the standard care at our institution. Post-partum care and breastfeeding recommendations are also addressed. Core tip: Inflammatory bowel diseases (IBD) are chronic inflammatory conditions characterized by relapsing and remitting episodes of intestinal inflammation. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While therapies have improved dramatically, IBDs have important effects on pregnancy and present challenges for maintaining optimal outcomes for mothers and their developing fetus/ neonate. Women with IBD and physician...

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“…In ammatory bowel diseases (IBD) most commonly affect women of childbearing age (1). The effect of the disease on women's fertility and pregnancies is a subject of controversy (2).…”

Section: Introductionmentioning

confidence: 99%

Pregnancy outcomes of women with inflammatory bowel disease

Tunç¹,

Akbulut²,

Parlak³

et al. 2013

Med gl Ins stit Zlatibor

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Background:In ammatory bowel diseases (IBD) generally affect women of childbearing age. In this study we investigated the effects of IBD on pregnancy, pregnancy outcomes and on newborns by comparing with a healthy control group.Methods: Data on the productive history were collected both in the question-and-answer format, and also from hospital records. The control group was made up of healthy volunteers of the same age group, who were living in the same region and who had a similar sociocultural structure. Control group data were also collected by asking questions on reproductive history in the question-and-answer format, and also from the obstetrical medical records.

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Epidemiology and the Natural Course of Inflammatory Bowel Disease

Cited by 261 publications

References 109 publications

Qualidade de vida de pacientes portadores de doença inflamatória intestinal

Qualidade de vida de pacientes portadores de doença inflamatória intestinal

Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management

Pregnancy outcomes of women with inflammatory bowel disease

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