Epidemiology and Susceptibility of 3,051
            <i>Staphylococcus aureus</i>
            Isolates from 25 University Hospitals Participating in the European SENTRY Study

Fluit, Ad C.; Wielders, C. L. C.; Verhoef, J.; Schmitz, F.-J.

doi:10.1128/jcm.39.10.3727-3732.2001

Cited by 249 publications

(164 citation statements)

References 17 publications

Supporting

Mentioning

131

Contrasting

Unclassified

Order By: Relevance

“…The frequency of infections and outbreaks due to MRSA considerably differs by country. It is extremely high in Japan, where it is around 60% (Otsuki and Nishino, 2000), while in Switzerland and The Netherlands this percentage is approximately 2% (Fluit et al, 2001), and in hospitals of the USA 26.9% of the S. aureus and 71.5% of CNS strains are methicillin resistant .…”

Section: Discussionmentioning

confidence: 98%

“…Since methicillin-resistant S. aureus (MRSA) was first recognised in England in 1961, MRSA strains have become common aetiologic agents of serious hospital infections in humans throughout the world (Fluit et al, 2001). According to the results of the SENTRY Antimicrobial Surveillance Program, between 1997 and 2000 the incidence of MRSA increased from 23% to 34% in Europe, from 26% to 36% in North America and from 49% to 54% in the AsiaPacific region.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Antibiotic resistance of staphylococci from humans, food and different animal species according to data of the Hungarian resistance monitoring system in 2001

Kaszanyitzky¹,

Jánosi²,

Egyed³

et al. 2003

Acta Veterinaria Hungarica

View full text Add to dashboard Cite

Based on data of the Hungarian resistance monitoring system the antibiotic resistance of Staphylococcus strains of human and animal origin was studied. No methicillin-resistant staphylococci harbouring mecA gene were isolated from animals in 2001. Penicillin resistance, mediated by penicillinase production, was the most frequent among Staphylococcus aureus strains isolated from humans (96%), from bovine mastitis (55%), from foods (45%) and from dogs. In staphylococci isolated from animals low resistance percentages to aminoglycosides (0-2%), fluoroquinolones (0.5-3%) and sulphonamides (0.5-4%) were found but in strains isolated humans these figures were higher (1-14%, 5-18% and 3-31%, r espectively). The most frequent antibiotic resistance profiles of strains isolated from animals and food were penicillin/tetracycline, penicillin/lincomycin and penicillin/lincomycin/tetracycline. Penicillin/tetracycline resistance was exhibited by strains from mastitis (3), samples from the meat industry (31), poultry flocks (1), poultry industry (1), noodle (1) and horses (2). Penicillin/lincomycin resistance was found in 10 Staphylococcus strains from mastitis, 1 from the dairy industry, 1 from the meat industry and 6 from dogs. Isolates from mastitis (2), from the dairy industry (2), from pigs (1), from the meat industry (1) and from poultry (1) harboured penicillin/lincomycin/tetracycline resistance pattern. Multiresistant strains were usually isolated only from one and sometimes from two animal species; therefore, the spread of defined resistant strains (clones) among different animal species could not be demonstrated. These results also suggest that the transfer of antibiotic resistance of S. aureus from animals to humans probably occurs less frequently than is generally assumed.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Antibiotic resistance of staphylococci from humans, food and different animal species according to data of the Hungarian resistance monitoring system in 2001

Kaszanyitzky¹,

Jánosi²,

Egyed³

et al. 2003

Acta Veterinaria Hungarica

View full text Add to dashboard Cite

show abstract

“…Apesar da menor freqüência de resistência de Staphylococcus aureus à linezolida, o achado de resistência associada a este antimicrobiano é preocupante, visto que esta droga tem sido considerada uma das últimas opções terapêuticas para infecções graves causadas por isolados de ORSA, frequentemente multirresistentes 7 . Desta forma, estes resultados sugerem o uso mais restrito da linezolida, a fim de garantir o máximo da sua atividade em infecções mais graves.…”

Section: Altas Taxas De Resistência Individual Entre Os Isolados Deunclassified

Determinação da resistência antimicrobiana associada em isolados clínicos de Staphylococcus aureus e Pseudomonas aeruginosa em um hospital público de Goiânia, Estado de Goiás

Kobayashi

Sadoyama

Vieira

2009

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Este estudo avaliou a resistência antimicrobiana associada de Pseudomonas aeruginosa e Staphylococcus aureus a um agente antimicrobiano com outras drogas. A resistência antimicrobiana associada foi calculada através do risco relativo. Houve uma relação óbvia entre resistência à oxacilina e a outros agentes antimicrobianos entre os isolados de Staphylococcus aureus resistentes à oxacilina (68,5%) superior a 32%, com exceção da linezolida (6,7%). Resistência associada pronunciada entre drogas foi observada para isolados de Pseudomonas aeruginosa, particularmente entre ciprofloxacina e os carbapenens (59,6% a 60,7%), entre aminoglicosídeos e carbapenens (66,3% a 67,7%) e os demais β-lactâmicos (52,3% a 85,8%). O presente trabalho enfatiza a importância da cultura diagnóstica e do teste de suscetibilidade na seleção de um correto agente antimicrobiano com relação ao impacto clínico no aumento da multirresistência e na seleção de resistência antimicrobiana associada.

show abstract

“…12 MRSA has become resistant to multiple other antimicrobial agents, including aminoglycosides, fluoroquinolones, tetracyclines and macrolideslincosamides-streptogramins. 13 Various MRSA control strategies have been proposed, ranging from contact precautions and active surveillance to topical treatment and more aggressive policies, such as the Dutch MRSA program. 14,15 A recent prospective study performed in two English ICUs, though, demonstrated no reduction of MRSA cross-infection with isolation/cohorting of MRSA-positive patients.…”

Section: Discussionmentioning

confidence: 99%

In vitro activity of minocycline combined with fosfomycin against clinical isolates of methicillin-resistant Staphylococcus aureus

et al. 2011

View full text Add to dashboard Cite

This study aimed to evaluate the in vitro activity of minocycline combined with fosfomycin against isolates of methicillinresistant Staphylococcus aureus (MRSA). A total of 87 clinical isolates of MRSA collected from three Chinese hospitals were included in the study. The checkerboard method with determination of the fractional IC index (FICI) was used to determine whether antibiotic combinations act synergistically against these isolates. The susceptibility results for minocycline and fosfomycin were interpreted according to the most relevant criteria. The results demonstrated the following interactions: 76 isolates (87.4%) showed synergistic interactions (FICIp0.5) and 11 isolates (12.6%) showed indifferent interactions (0.5oFICIo4). No antagonistic interactions (FICIX4) were observed. The combination of minocycline and fosfomycin can be synergistic against MRSA. Further studies are required to determine the potential clinical role of this combination regimen as a therapeutic alternative for certain types of MRSA infections.

show abstract

Epidemiology and Susceptibility of 3,051 Staphylococcus aureus Isolates from 25 University Hospitals Participating in the European SENTRY Study

Cited by 249 publications

References 17 publications

Antibiotic resistance of staphylococci from humans, food and different animal species according to data of the Hungarian resistance monitoring system in 2001

Antibiotic resistance of staphylococci from humans, food and different animal species according to data of the Hungarian resistance monitoring system in 2001

Determinação da resistência antimicrobiana associada em isolados clínicos de Staphylococcus aureus e Pseudomonas aeruginosa em um hospital público de Goiânia, Estado de Goiás

In vitro activity of minocycline combined with fosfomycin against clinical isolates of methicillin-resistant Staphylococcus aureus

Contact Info

Product

Resources

About