Epidemiology and prevention of surgical site infections after cardiac surgery

Lepelletier, Didier; Bourigault, C.; Roussel, J; Lasserre, Camille; Leclère, Brice; Corvec, Stéphane; Pattier, Sabine; Lepoivre, Thierry; Baron, Olivier; Despins, Philippe

doi:10.1016/j.medmal.2013.07.003

Cited by 71 publications

(74 citation statements)

References 43 publications

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“…The contamination of the surgical site is often derived from the commensal flora of the human body (patient or health care team) [5]. …”

Section: Discussionmentioning

confidence: 99%

“…Factors contributing to the development of post-surgical mediastinitis are multiple and dependent on the type of surgery: covers of sternotomy; postoperative bleeding and those dependent on patient history including chronic obstructive pulmonary disease, smoking, diabetes and obesity [1, 2, 5, 6, 8, 10]. …”

Section: Discussionmentioning

confidence: 99%

“…Treatment of mediastinitis includes: the treatment of septic shock and associated visceral failures, antibiotic therapy and aspiration guided by ultrasound or surgical exploration with drainage [2, 5, 11]. …”

Section: Discussionmentioning

confidence: 99%

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Exceptional association of two species of bacteria causing mediastinitis: Haemophilus influenzae (H. influenzae) and Aggregatibacter aphrophilus (A. aphrophilus)

et al. 2018

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BackgroundPost cardiac surgery mediastinitis is the major infectious complication, despite the development of surgical techniques and the application of strict preventive measures.The Haemophilus influenzae mediastinitis is very rare. The mediastinitis caused by the association between Haemophilus influenzae and Aggregatibacter aphrophilus has never been described to our knowledge.Case presentationWe report the case of an exceptional combination of Haemophilus influenzae and Aggregatibacter aphrophilus in a patient operated for single bypass which is complicated by mediastinitis the 10th day after the surgical act.ConclusionThe conclusion to be drawn from this work is to think in unusual seeds in case of mediastinitis post cardiac surgery for the elaboration of recommendations for antibiotic prophylaxis.

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“…The contamination of the surgical site is often derived from the commensal flora of the human body (patient or health care team) [5]. …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Exceptional association of two species of bacteria causing mediastinitis: Haemophilus influenzae (H. influenzae) and Aggregatibacter aphrophilus (A. aphrophilus)

et al. 2018

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“…; therefore, clinicians may not consider them a source of GNRB. According to the literature, Gram-negative organisms account for 22e28.3% of mediastinitis, 12,13 and 20e30% of surgical site infections. 3,14 This study provides evidence that several factors are associated with increased mortality from GNRB after CVS.…”

Section: Discussionmentioning

confidence: 99%

Gram-negative rod bacteremia after cardiovascular surgery: Clinical features and prognostic factors

Tago

Hirai

Ainoda

et al. 2017

Journal of Microbiology, Immunology and Infection

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“…In fact, an increase in the amount of Staphylococcus aureus has been reported in patients treated with VAC as well as in a case of staphylococcal toxic syndrome (29)(30)(31). S. aureus is very common in post-sternotomy mediastinitis (32,33) and its incidence has been shown to be as high as 40% in one study (34). However, from the wound swabs analysed by in our study, it was found that coagulase-negative staphylococci (31⋅5%) and coliforms (27⋅4%) were reported most frequently ( Table 2).…”

Section: Discussionmentioning

confidence: 99%

Assessment of vacuum‐assisted closure therapy on the wound healing process in cardiac surgery

Pericleous

Dimitrakakis

Photiades

et al. 2015

International Wound Journal

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Postoperative deep sternal wound infection (DSWI) is a serious complication in cardiac surgery (1-5% of patients) with high mortality and morbidity rates. Vacuum-assisted closure (VAC) therapy has shown promising results in terms of wound healing process, postoperative hospital length of stay and lower in-hospital costs. The aim of our retrospective study is to report the outcome of patients with DSWI treated with VAC therapy and to assess the effect of contributory risk factors. Data of 52 patients who have been treated with VAC therapy in a single institution (study period: September 2003-March 2012) were collected electronically through PAtient Tracking System PATS and statistically analysed using SPSS version 20. Of the 52 patients (35 M: 17 F), 88·5% (n = 46) were solely treated with VAC therapy and 11·5% (n = 6) had additional plastic surgical intervention. Follow-up was complete (mean 33·8 months) with an overall mortality rate of 26·9% (n = 14) of whom 50% (n = 7) died in hospital. No death was related to VAC complications. Patient outcomes were affected by pre-operative, intra-operative and postoperative risk factors. Logistic EUROscore, postoperative hospital length of stay, advanced age, chronic obstructive pulmonary disease (COPD) and long-term corticosteroid treatment appear to be significant contributing factors in the long-term survival of patients treated with VAC therapy.

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Epidemiology and prevention of surgical site infections after cardiac surgery

Cited by 71 publications

References 43 publications

Exceptional association of two species of bacteria causing mediastinitis: Haemophilus influenzae (H. influenzae) and Aggregatibacter aphrophilus (A. aphrophilus)

Exceptional association of two species of bacteria causing mediastinitis: Haemophilus influenzae (H. influenzae) and Aggregatibacter aphrophilus (A. aphrophilus)

Gram-negative rod bacteremia after cardiovascular surgery: Clinical features and prognostic factors

Assessment of vacuum‐assisted closure therapy on the wound healing process in cardiac surgery

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