Epidemiology and perinatal services

Martin, Richard J.; Fanaroff, Avroy A.; Walsh, Michele C.

doi:10.1016/b978-0-323-06545-0.00011-x

Cited by 3 publications

(8 citation statements)

References 44 publications

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“…The predominant clinical feature of malaria in neonates is fever (88-100%). Other manifestations include respiratory distress (20-57%), pallor and anemia (38% each), hepatomegaly (31-80%), refusal to feed (40-70%), and jaundice and diarrhea (25% each) [11][12]15]. In this case series, none of the neonates had fever at presentation.…”

Section: Discussionmentioning

confidence: 74%

“…Malaria in neonates is caused by Plasmodium infection. Mother-to-newborn transmission, a bite from an infected anopheles mosquito, and transfusion of infected blood are the modes of transmission [12][13]. Even though one of the mothers in the case series had a malaria diagnosis during pregnancy, it was challenging to determine whether the malaria infection in the case series was congenital or acquired neonatal malaria.…”

Section: Discussionmentioning

confidence: 99%

“…The predominant clinical feature of malaria in neonates is fever (88-100%). Other manifestations include respiratory distress, pallor and anemia, hepatomegaly, refusal to feed, jaundice, and diarrhea [11,12]. The signs and symptoms are similar to those of neonatal sepsis and congenital TORCH (Toxoplasmosis, Others (syphilis, hepatitis B), Rubella, Cytomegalovirus, Herpes simplex) infections and may cause misdiagnoses.…”

Section: Introductionmentioning

confidence: 99%

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Plasmodium Falciparum neonatal malaria with atypical presentation: A case series from southwestern Ethiopia

Tesso,

Gossaye,

Bekena

et al. 2024

Preprint

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Introduction: Neonatal malaria detection of asexual stages of plasmodium species within the first 28 days of life. It can be congenital or acquired through mosquito bites or blood transfusions. Neonatal malaria is generally considered to be rare due to the multiple innate and acquired physiological protective effects present in neonates. However, in areas where malaria is endemic, the prevalence of malaria in neonates is high. The predominant clinical feature of malaria in neonates is fever. respiratory distress, pallor and anemia, hepatomegaly, refusal to feed, jaundice and diarrhea can be manifestations. Atypical presentations without fever can lead to inaccurate diagnosis and contribute to neonatal morbidity and mortality. Neonates from endemic areas with any of the above symptoms should be screened for malaria. Case presentation: We present a series of three cases of Neonatal plasmodium falciparum malaria Presented atypically without febrile episodes, who were diagnosed at Mizan-Tepi University Teaching Hospital between July and September 2023. The first patient presented with vomiting, refusal to feed, pallor, severe anemia, and splenomegaly. The second patient presented with an inconsolable cry, failure to pass feces, abdominal distention, and anemia. The third patient presented with vomiting and anemia. All patients received a 7-day course of intravenous artesunate; the first patient also received a blood transfusion. All patients recovered and were discharged. Conclusions Partial immunity resulting from repeated malaria infections in endemic regions may result in the transfer of high levels of maternal Immunoglobulin G (IgG) antibodies through the placenta, which bind to various plasmodial components and can produce different atypical clinical presentations. In malaria-endemic areas, neonates presenting with any of the presenting signs and symptoms of malaria, including afebrile presentation, require malaria screening to avoid delays in diagnosis.

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Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Plasmodium Falciparum neonatal malaria with atypical presentation: A case series from southwestern Ethiopia

Tesso,

Gossaye,

Bekena

et al. 2024

Preprint

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“…ABS with multifactorial etiology is a congenital anomaly of the fetus, in which the fetal body parts have deformities due to amniotic band wrapped around them, resulting in fetal structural abnormalities and dysfunctions [1]. Usually, the diagnosis is made by deformities that are consistent with amniotic bands (such as limb deformities) in the absence of visible bands [2]. Prenatal diagnosis of ABS mainly depends on fetal ultrasound (US) scans [1].…”

Section: Introductionmentioning

confidence: 99%

“…Prenatal diagnosis of ABS mainly depends on fetal ultrasound (US) scans [1]. But it is difficult to identify the amniotic bands with standard prenatal imaging, including ultrasound and MRI [2]. It has been reported to have the prevalence of 0.19 to 8.1 per 10000 live births [3].…”

Section: Introductionmentioning

confidence: 99%

A neonate with Amniotic Band Syndrome and osteomyelitis

Zafaranloo¹,

Mohagheghi²,

Beigi³

et al. 2023

JENT

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Amniotic band syndrome (ABS) comprises of a broad term for a group of congenital anomalies involving the limbs more often, but any other anatomic region of fetus could be involved. The prevalence of amniotic band has been reported from 0.19 to 8.1 per 10000 live births. Different theories exist for explaining the etiology of amniotic bands, but it has been considered to have a multifactorial etiology. Fetoscopic release of amniotic bands affecting one or more extremities can prevent limb loss or preserve limb function when distal fellow is still identifiable on preoperative ultrasound scans. Congenital anomalies of amniotic band syndrome will happen approximately in 77% of fetuses. There has been reported equal involvement between male and female. In general, we do not have osteomyelitis in neonates, but it would be connected to a long-term hospital admission and possible long‐term complications if not diagnosed on time. The long bones are the most frequently affected sites. Here we are introducing a neonate with left upper extremity necrosis due to ABS which needed amputation and it was associated with severe chronic osteomyelitis.

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Epidemiology of Low Birth Weight in the Town of Sidi Bel Abbes (West of Algeria): A Case-Control Study

H¹

2014

J Nutr Food Sci

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Introduction:The Low birth weight is defined as a live birth weighting less than 2500 g and it is considered to be a major determinant of the child survival, his health and development.Objective: This study examined the frequency and risk factors that influence birth weight <2.5 kg (LBW) in the region of Sidi bel Abbes (west of Algeria). Materials and methods:A descriptive prospective case-control study was done during the period of June 2012 to January 2013. Total samples were 1828 pregnant women and their newborns in neonatology department of Hospital Obstetrics and Gynecology in Sidi bel Abbes west Algeria. Results:At the end of this work, it appears a prevalence of 1828 new born, including maximum newborn babies 92.97% had birth weight 2.5 Kg or more and 128 newborns with low birth weight <2.5 Kg, or a rate of 7.02%. It was found that mean weight of newborn babies was 3386.95 ± 560.70 (g). This study confirms the close association between low birth weight newborn and prematurity, primiparity, short interpregnancy interval, multiple pregnancy, previous history of low birth weight, delayed of first antenatal visit, low pre-pregnancy BMI, gestational weight gain less than the recommendations, primary educated mothers, other complications and diseases which contributed to high prevalence of LBW included hypertension and gestational diabetes. Conclusion:It is essential to do a searching for pregnancies with higher risk of LWB like those who are primiparous or have short birth intervals, and it is also important to have better and more attentive prenatal care in order to reduce the incidence of LBW.

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Epidemiology and perinatal services

Cited by 3 publications

References 44 publications

Plasmodium Falciparum neonatal malaria with atypical presentation: A case series from southwestern Ethiopia

Plasmodium Falciparum neonatal malaria with atypical presentation: A case series from southwestern Ethiopia

A neonate with Amniotic Band Syndrome and osteomyelitis

Epidemiology of Low Birth Weight in the Town of Sidi Bel Abbes (West of Algeria): A Case-Control Study

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