Epidemiology and outcomes from out-of-hospital cardiac arrests in England

Hawkes, Claire; Booth, Scott; Ji, Chen; Brace-McDonnell, Samantha J.; Whittington, Andrew; Mapstone, James; Cooke, Matthew; Deakin, Charles D.; Gale, Chris P; Fothergill, Rachael; Nolan, Jerry P.; Rees, Nigel; Soar, Jasmeet; Siriwardena, Aloysius Niroshan; Brown, Terry; Perkins, Gavin D.

doi:10.1016/j.resuscitation.2016.10.030

Cited by 277 publications

(226 citation statements)

References 28 publications

Supporting

Mentioning

184

Contrasting

Unclassified

Order By: Relevance

“…The incidence of OHCA was comparable to other countries such as England (53), North America (56) and Denmark (62) . Also similar to international services such as England, the proportion of OHCA occurring in males was higher than that of females …”

Section: Discussionsupporting

confidence: 68%

Incidence and outcomes of out‐of‐hospital cardiac arrest: A New Zealand perspective

Dicker

Davey

Smith

et al. 2018

Emerg Medicine Australasia

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 68%

Incidence and outcomes of out‐of‐hospital cardiac arrest: A New Zealand perspective

Dicker

Davey

Smith

et al. 2018

Emerg Medicine Australasia

View full text Add to dashboard Cite

show abstract

“…A systematic review of cardiac arrest randomised controlled trials published between 2002 and 2012 identified 61 trials, of which only three (5%) included in-hospital cardiac arrest patients [29]. Differences between out-of-hospital and in-hospital cardiac arrest in terms of patient characteristics and clinical response limit the direct generalisability of research findings between these settings [1, 30]. Furthermore, it likely means that experience and lessons learned from the successful delivery of out-of-hospital cardiac arrest research cannot necessarily be directly transferred to the in-hospital setting [31].…”

Section: Discussionmentioning

confidence: 99%

Mechanical versus manual chest compressions in the treatment of in-hospital cardiac arrest patients in a non-shockable rhythm: a randomised controlled feasibility trial (COMPRESS-RCT)

Couper

Quinn

Lall

et al. 2018

Scand J Trauma Resusc Emerg Med

Self Cite

View full text Add to dashboard Cite

BackgroundMechanical chest compression devices consistently deliver high-quality chest compressions. Small very low-quality studies suggest mechanical devices may be effective as an alternative to manual chest compressions in the treatment of adult in-hospital cardiac arrest patients. The aim of this feasibility trial is to assess the feasibility of conducting an effectiveness trial in this patient population.MethodsCOMPRESS-RCT is a multi-centre parallel group feasibility randomised controlled trial, designed to assess the feasibility of undertaking an effectiveness to compare the effect of mechanical chest compressions with manual chest compressions on 30-day survival following in-hospital cardiac arrest.Over approximately two years, 330 adult patients who sustain an in-hospital cardiac arrest and are in a non-shockable rhythm will be randomised in a 3:1 ratio to receive ongoing treatment with a mechanical chest compression device (LUCAS 2/3, Jolife AB/Stryker, Lund, Sweden) or continued manual chest compressions. It is intended that recruitment will occur on a 24/7 basis by the clinical cardiac arrest team. The primary study outcome is the proportion of eligible participants randomised in the study during site operational recruitment hours. Participants will be enrolled using a model of deferred consent, with consent for follow-up sought from patients or their consultee in those that survive the cardiac arrest event.The trial will have an embedded qualitative study, in which we will conduct semi-structured interviews with hospital staff to explore facilitators and barriers to study recruitment.DiscussionThe findings of COMPRESS-RCT will provide important information about the deliverability of an effectiveness trial to evaluate the effect on 30-day mortality of routine use of mechanical chest compression devices in adult in-hospital cardiac arrest patients.Trial registrationISRCTN38139840, date of registration 9th January 2017.Electronic supplementary materialThe online version of this article (10.1186/s13049-018-0538-6) contains supplementary material, which is available to authorized users.

show abstract

“…un-witnessed cardiac arrest, no bystander CPR for more than 15 minutes, asystolic rhythm and absence of a potentially reversible cause (e.g. hypothermia)) may lead to resuscitation being withheld (27). In other countries resuscitation would be provided in such circumstances (28).…”

Section: Smart Technologies For Activation Of Lay Respondersmentioning

confidence: 99%

Out-of-hospital cardiac arrest: prehospital management

2018

View full text Add to dashboard Cite

(no more than 150 words)Sudden out of hospital cardiac arrest is the most time critical medical emergency. In this expert opinion and literature review, we consider important issues in the pre-hospital management of cardiac arrest. Successful resuscitation is reliant on a strong chain of survival drawn from the community, dispatch center, ambulance and hospital working together. Early cardiopulmonary resuscitation and defibrillation has the greatest impact on survival. If the community response does not restart the heart, resuscitation is continued by emergency medical services staff. There is uncertainty about the best approaches for airway management and the effectiveness of current drug treatments. Prognostic factors and termination of resuscitation rules may guide the duration of a resuscitation attempt and decision to transport to hospital. If return of spontaneous circulation is achieved, the focus of treatment shifts to stabilization, restoring normal physiological parameters and transporting to hospital for on-going care.2

show abstract

Epidemiology and outcomes from out-of-hospital cardiac arrests in England

Abstract: Introduction: This study reports the epidemiology and outcomes from out-of-hospital

Cited by 277 publications

References 28 publications

Incidence and outcomes of out‐of‐hospital cardiac arrest: A New Zealand perspective

Incidence and outcomes of out‐of‐hospital cardiac arrest: A New Zealand perspective

Mechanical versus manual chest compressions in the treatment of in-hospital cardiac arrest patients in a non-shockable rhythm: a randomised controlled feasibility trial (COMPRESS-RCT)

Out-of-hospital cardiac arrest: prehospital management

Contact Info

Product

Resources

About