Epidemiology and outcome of pediatric acute respiratory distress syndrome according to pediatric acute lung injury consensus conference 2015 (PALICC) definition: A single center prospective study

Vinayaka, HS; Basavaraj, GV; Kumar, T Ramesh; Benakappa, Asha

doi:10.21304/2017.0404.00209

Cited by 1 publication

(1 citation statement)

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“…For testing with a closed suction catheter, the T-piece closed suction catheter with Ballard technology (14Fr (adult) or 12Fr (paediatric), Halyard Health, United States) was placed between the wye and ETT. The ventilator settings used to simulate adult ( 24 ), and paediatric (30-kg patient) mechanical ventilation ( 27 , 28 , 29 ) are listed in Table 2 . The ventilator bias flow for each test condition was recorded at the wye using a flow sensor as previously described in Joyce et al ( 30 ).…”

Section: Methodsmentioning

confidence: 99%

An in vitro study of the effects of respiratory circuit setup and parameters on aerosol delivery during mechanical ventilation

Reilly,

Mac Giolla Eain,

Murphy

et al. 2024

Front. Med.

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IntroductionAerosol therapy is often prescribed concurrently during invasive mechanical ventilation (IMV). This study determines the effects of nebuliser position, circuit humidification source, and most importantly, lung health on the delivery of aerosol in simulated adult and paediatric IMV patients. Furthermore, the influence of closed suction catheters on aerosol delivery is also addressed.MethodsA vibrating mesh nebuliser was used to deliver Albuterol to simulated adult and paediatric IMV patients with differing states of lung health. Four different nebuliser positions and two types of humidification were analysed. Closed suction catheter mounts, a mainstay in IMV therapy, were incorporated into the circuits. The mean ± SD dose of aerosol (%) was assayed from a filter at the distal end of the endotracheal tube.ResultsNebuliser placement and circuit humidification source had no effect on the delivered dose (%) in adults, yet both significantly did in the simulated paediatric patients. The use of closed suction catheter mounts significantly reduced the delivered dose (%) in adults but not in paediatric patients. A simulated healthy lung state generated the largest delivered dose (%), irrespective of nebuliser position in the adult. However, different lung health and nebuliser positions yielded higher delivered doses (%) in paediatrics.ConclusionLung health and respiratory circuit composition significantly affect aerosol delivery in both adult and paediatric IMV patients. Nebuliser placement and respiratory circuit humidification source do not affect the delivered dose in adult but do in paediatric IMV patients.

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