Epidemiology and medical cost of hospitalization due to rotavirus gastroenteritis among children under 5 years of age in the central-east of Tunisia

Soltani, M.S.; Salah, A. Ben; Bouanène, Inès; Trabelsi, Abdelhalim; Sfar, Mohamed Taher; Harbi, A.; Gueddiche, M; Farhat, Essia Ben

doi:10.26719/2015.21.8.584

Cited by 10 publications

(14 citation statements)

References 23 publications

(16 reference statements)

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“…G1P [8] was the most prevalent in 11 of those studies, accounting for between 6 (6%) and 171 (69%) of genotyped RV gastroenteritis samples in those countries. G9P [8] (34,35). In addition, G2P [4] was detected in all countries except Islamic Republic of Iran, Tunisia, and UAE.…”

Section: Distribution Of Human Rv G and P Combination In Children Witmentioning

confidence: 92%

“…Overall, G1P [8] combination represented the predominant genotype followed by G9P [8] and G2P [4] in the MENA region, in 1535 (37.7%), 916 (22.5%), and 331 (8.1%) of all RV positive samples, respectively. G1P [8] combination was detected in 14 studies from 10 countries (10,11,14,(23)(24)(25)28,29,31,32,(34)(35)(36)(37). G1P [8] was the most prevalent in 11 of those studies, accounting for between 6 (6%) and 171 (69%) of genotyped RV gastroenteritis samples in those countries.…”

Section: Distribution Of Human Rv G and P Combination In Children Witmentioning

confidence: 96%

“…We reviewed 145 articles/abstracts to select a total of 28 that met the inclusion criteria of the current review (Figure 1). The selected studies covered Bahrain (10), Egypt (11,12), Islamic Republic of Iran (13)(14)(15)(16)(17)(18)(19)(20)(21), Iraq (22,23), Jordan (24,25), Libya (26), Morocco (27)(28)(29), Saudi Arabia (30-32), Tunisia (33), Turkey (34,35), United Arab Emirates (UAE) (36), and Yemen (37). All studies from Algeria, Jordan, Leb-anon, Oman, Palestine, and Qatar were excluded because these did not meet our inclusion criteria whereas no studies were available from Kuwait and the Syrian Arab Republic.…”

Section: Studies Selected For Reviewmentioning

confidence: 99%

“…Nineteen studies from nine countries including Bahrain (10), Islamic Republic of Iran (13,(15)(16)(17)(18)(19)(20)(21), Iraq (22), Jordan (25), Morocco (29), Saudi Arabia (30-32), Tunisia (33), Turkey (34,35), and Yemen (37) contained data on gender distribution. All studies found that the frequency of diarrhoea for Rotavirus was higher in males ( Table 2).…”

Section: Gender Distribution Of Children With Rv Gastroenteritismentioning

confidence: 99%

“…Out of 28 studies, 15 studies from 11 countries -Bahrain (10), Egypt (11), Islamic Republic of Iran (14), Iraq (23), Jordan (24,25), Morocco (28,29), Saudi Arabia (31,32), Tunisia (33), Turkey (34,35), UAE (36) and Yemen (37) -studied the human RV G-P combinations in 4070 hospitalized children with RV gastroenteritis. Overall, G1P [8] combination represented the predominant genotype followed by G9P [8] and G2P [4] in the MENA region, in 1535 (37.7%), 916 (22.5%), and 331 (8.1%) of all RV positive samples, respectively.…”

Section: Distribution Of Human Rv G and P Combination In Children Witmentioning

confidence: 99%

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Rotavirus gastroenteritis among hospitalized children under 5 years of age in the Eastern Mediterranean Region: a review

Shaheen¹

2019

East Mediterr Health J

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Background: Rotavirus(RV) is one of the primary causes globally of acute diarrhoea in children below 5 years of age. Aims: This literature research aims to evaluate the rotavirus diarrhoea among hospitalized children < 5 years of age in the Eastern Mediterranean Region from 2010 to 2016. Data from each country were extracted and compared. Methods: An extensive literature search was carried out using the following databases: PubMed, Google Scholar and Science Direct, with the keyword "Rotavirus". The search was limited to articles published from January 2010 to December 2016. Results: The search identified 28 studies. Rotavirus gastroenteritis (RVGE) identification in studies countries ranged from from 19%-78.2% of all tested diarrhoeal specimens, primarily in children ≤ 1 year of age. RV occurred throughout the year, with peak incidence during autumn and winter seasons. G1P[8] was the predominant circulating genotype combination followed by G9P[8] and G2P[4]. Out of 28 studies, only one examined the economic burden which ranged from US$ 245 to $345 per hospitalized child due to RV diarrhoea. Moreover, three days were the minimum duration of hospitalization. No available data on the mortality rates due to RVGE among the selected studies. Conclusions: This research documents that RV is one of the most significant pathogens that cause morbidity and mortality in the paediatric population in Eastern Mediterranean Region countries. The data from this literature research may help public healthcare workers in decreasing mortality and morbidity resulting from RVGE in the region.

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Section: Distribution Of Human Rv G and P Combination In Children Witmentioning

confidence: 92%

Section: Distribution Of Human Rv G and P Combination In Children Witmentioning

confidence: 96%

Section: Studies Selected For Reviewmentioning

confidence: 99%

Section: Gender Distribution Of Children With Rv Gastroenteritismentioning

confidence: 99%

Section: Distribution Of Human Rv G and P Combination In Children Witmentioning

confidence: 99%

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Rotavirus gastroenteritis among hospitalized children under 5 years of age in the Eastern Mediterranean Region: a review

Shaheen¹

2019

East Mediterr Health J

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Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar

Mathew

Ansari

Thani

et al. 2021

Eur J Clin Microbiol Infect Dis

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Cost of Nine Pediatric Infectious Illnesses in Low- and Middle-Income Countries: A Systematic Review of Cost-of-Illness Studies

Broucker¹,

Sim

Brenzel

et al. 2020

PharmacoEconomics

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Background Cost-of-illness data from empirical studies provide insights into the use of healthcare resources including both expenditures and the opportunity cost related to receiving treatment. Objective The objective of this systematic review was to gather cost data and relevant parameters for hepatitis B, pneumonia, meningitis, encephalitis caused by Japanese encephalitis, rubella, yellow fever, measles, influenza, and acute gastroenteritis in children in low- and middle-income countries. Data Sources Peer-reviewed studies published in public health, medical, and economic journals indexed in PubMed (MEDLINE), Embase, and EconLit. Study Eligibility Criteria, Participants, and Interventions Studies must (1) be peer reviewed, (2) be published in 2000–2016, (3) provide cost data for one of the nine diseases in children aged under 5 years in low- and middle-income countries, and (4) generated from primary data collection. Limitations We cannot exclude missing a few articles in our review. Measures were taken to reduce this risk. Several articles published since 2016 are omitted from the systematic review results, these articles are included in the discussion. Conclusions and Implications of Key Findings The review yielded 37 articles and 267 sets of cost estimates. We found no cost-of-illness studies with cost estimates for hepatitis B, measles, rubella, or yellow fever from primary data. Most estimates were from countries in Gavi preparatory (28%) and accelerated (28%) transition, followed by those who are initiating self-financing (22%) and those not eligible for Gavi support (19%). Thirteen articles compared household expenses to manage illnesses with income and two articles with other household expenses, such as food, clothing, and rent. An episode of illness represented 1–75% of the household’s monthly income or 10–83% of its monthly expenses. Articles that presented both household and government perspectives showed that most often governments incurred greater costs than households, including non-medical and indirect costs, across countries of all income statuses, with a few notable exceptions. Although limited for low- and middle-income country settings, cost estimates generated from primary data collection provided a ‘real-world’ estimate of the economic burden of vaccine-preventable diseases. Additional information on whether common situations preventing the application of official clinical guidelines (such as medication stock-outs) occurred would help reveal deficiencies in the health system. Improving the availability of cost-of-illness evidence can inform the public policy agenda about healthcare priorities and can help to operationalize the healthcare budget in local health systems to respond adequately to the burden of illness in the community.

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Epidemiology and medical cost of hospitalization due to rotavirus gastroenteritis among children under 5 years of age in the central-east of Tunisia

Cited by 10 publications

References 23 publications

Rotavirus gastroenteritis among hospitalized children under 5 years of age in the Eastern Mediterranean Region: a review

Rotavirus gastroenteritis among hospitalized children under 5 years of age in the Eastern Mediterranean Region: a review

Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar

Cost of Nine Pediatric Infectious Illnesses in Low- and Middle-Income Countries: A Systematic Review of Cost-of-Illness Studies

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