2019
DOI: 10.17305/bjbms.2019.4053
|View full text |Cite
|
Sign up to set email alerts
|

Epidemiology and mechanism of drug resistance of Mycoplasma pneumoniae in Beijing, China: A multi-center study

Abstract: Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community-acquired respiratory tract infections (RTIs). We aimed to investigate the prevalence of M. pneumoniae infection, antibiotic resistance and genetic diversity of M. pneumoniae isolates across multiple centers in Beijing, China. P1 protein was detected by Nested PCR to analyze the occurrence of M. pneumoniae in pediatric patients with RTI. M. pneumoniae isolates were cultured and analyzed by Nested-PCR to determine their genotypes… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

5
33
2
1

Year Published

2020
2020
2023
2023

Publication Types

Select...
6
3

Relationship

0
9

Authors

Journals

citations
Cited by 32 publications
(41 citation statements)
references
References 36 publications
(46 reference statements)
5
33
2
1
Order By: Relevance
“…The mutation rate in this study was 56.07%, of which were all A2063G mutations. The rate of drug-resistant MP was lower than those reported in other studies in China, where the rates range from almost 70% to 90% [21][22][23] . This is the because point mutations in drug-resistance genes were detected by PCR in this study, while drug sensitivity tests were chosen by other researchers.…”
Section: Discussioncontrasting
confidence: 73%
“…The mutation rate in this study was 56.07%, of which were all A2063G mutations. The rate of drug-resistant MP was lower than those reported in other studies in China, where the rates range from almost 70% to 90% [21][22][23] . This is the because point mutations in drug-resistance genes were detected by PCR in this study, while drug sensitivity tests were chosen by other researchers.…”
Section: Discussioncontrasting
confidence: 73%
“…The mutation rate in this study was 56.07%, of which were all A2063G mutations. The rate of drug-resistant MP was lower than those reported in other studies in China, where the rates range from almost 70 to 90% [21,22,24]. This is the because point mutations in drug-resistance genes were detected by PCR in this study, while drug sensitivity tests were chosen by other researchers.…”
Section: Discussionmentioning
confidence: 57%
“…Drug resistance is another inevitable factor contributing to the development of RMPP [8] . Mutations at position 2063 or 2064 domain V in the 23S rRNA gene are considered to be related to macrolide resistance [22,23] . The mutation rate in this study was 56.07%, of which were all A2063G mutations.…”
Section: Discussionmentioning
confidence: 99%