Epidemiology and Economic Impact of Foot Ulcers

Boyko, Edward J.; Monteiro‐Soares, Matilde

doi:10.1002/9781119445821.ch1

Cited by 6 publications

(6 citation statements)

References 84 publications

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“…These conditions contribute to impaired wound repair, heightened susceptibility to infection and in extreme instances, necrosis of the affected limb. 3,4 The conventional methodology for overseeing diabetic ulcers comprises an array of interventions, such as diligent glycaemic regulation, debridement, infection prevention, revascularization and sophisticated wound care modalities. 5 Notwithstanding these traditional interventions, prognosis for diabetic lower limb lesions continues to be uncertain, thereby necessitating the development of novel adjunct therapies.…”

Section: Introductionmentioning

confidence: 99%

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The efficacy of electroacupuncture in among early diabetic patients with lower limb arteriosclerotic wounds

Sang,

Zhao,

Yang

2023

International Wound Journal

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Diabetic foot ulcers are the prevalent complication of diabetes mellitus, frequently culminating in arteriosclerosis of the lower extremities and consequent development of chronic wounds. The effectiveness of electroacupuncture (EA) as therapeutic intervention for promoting wound healing in this particular group of patients has been comprehensively assessed in this study. A randomized controlled trial involving 380 early diabetic patients with arteriosclerotic lesions of the lower limbs was conducted. Standard wound care plus EA was administered to the treatment group, while standard wound care alone was administered to the control group. The principal outcome assessed was the reduction in lesion size following the 8‐week treatment period. Pain scores, recuperation time, and quality of life (QoL) evaluations constituted secondary outcomes. In comparison to the control group, the treatment group exhibited a significantly greater reduction in wound size (p < 0.05). The treatment group exhibited significantly reduced pain scores and significantly higher QoL scores (p < 0.05). The duration of recovery did not vary substantially among the groups (p > 0.05). Electroacupuncture thus appeared to be an effective adjunctive treatment for early diabetic patients with lower limb arteriosclerotic lesions, promoting pain relief and quality of life. Additional investigation is necessary to validate these results and delve into the underlying mechanisms of action.

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Section: Introductionmentioning

confidence: 99%

“…The wounds in question are frequently ascribed to the convergence of peripheral arterial disease, diabetic peripheral neuropathy, and immune dysfunction. These conditions contribute to impaired wound repair, heightened susceptibility to infection and in extreme instances, necrosis of the affected limb 3,4 …”

Section: Introductionmentioning

confidence: 99%

The efficacy of electroacupuncture in among early diabetic patients with lower limb arteriosclerotic wounds

Sang,

Zhao,

Yang

2023

International Wound Journal

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“…Millions of Americans are affected by peripheral vascular disorders associated with pain, functional impairment, amputation, and higher risk of death (Nelson et al, 2007;Sen et al, 2009;Boyko et al, 2018). In addition, diabetes affects the entire vascular system due to long duration of high blood glucose levels, which causes changes in blood viscosity and arterial wall tension.…”

Section: Foot Ulcer Imagingmentioning

confidence: 99%

Dual-modal photoacoustic and ultrasound imaging: from preclinical to clinical applications

Nyayapathi,

Zheng,

Zhou

et al. 2024

Front. Photon.

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Photoacoustic imaging is a novel biomedical imaging modality that has emerged over the recent decades. Due to the conversion of optical energy into the acoustic wave, photoacoustic imaging offers high-resolution imaging in depth beyond the optical diffusion limit. Photoacoustic imaging is frequently used in conjunction with ultrasound as a hybrid modality. The combination enables the acquisition of both optical and acoustic contrasts of tissue, providing functional, structural, molecular, and vascular information within the same field of view. In this review, we first described the principles of various photoacoustic and ultrasound imaging techniques and then classified the dual-modal imaging systems based on their preclinical and clinical imaging applications. The advantages of dual-modal imaging were thoroughly analyzed. Finally, the review ends with a critical discussion of existing developments and a look toward the future.

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“…In association with the infection, it increases the risk of mortality among the diabetic population, having an adverse impact both clinically and economically ( 20 ). Ischemia in the form of peripheral arterial disease provides an important contribution to causing diabetic foot, which mainly affects the lower limb, specifically the parts distal to the knee joint ( 21 ). In patients with diabetes, the risk of developing a diabetic foot ulcer is between 19 and 34% ( 18 ).…”

Section: Introductionmentioning

confidence: 99%

Risk assessment of amputation in patients with diabetic foot

Tănăsescu

Sabău²,

Moisin³

et al. 2022

Exp Ther Med

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The prevalence of diabetes has increased dramatically over the past decade, especially in developing countries, reaching pandemic proportions. Although has been the most important factor influencing the prevalence of type 2 diabetes, the prevalence of type 2 diabetes is on the increase among younger adults. The subsequent rate of increase with age is variable, which is more evident in societies where the general prevalence of the disease is higher. Based on clinical and statistical data obtained from the patients who were admitted to The First and Second Surgery Wards in the Sibiu County Emergency University Clinical Hospital (Sibiu, Romania) and the Proctoven Clinic (Sibiu, Romania) between January 2018 and December 2020, the present study attempted to devise a risk score that can be applied for the benefit of patients. The ultimate aim was that this risk score may be eventually applied by diabetologists and surgeons to assess the risk of amputation in patients with diabetic foot lesions. An important part in the therapeutic management of diabetic foot injuries is the assessment of risk factors. Using this risk score system devised, the risk factors that were found to exert influence in aggravating diabetic foot injuries are smoking, obesity, dyslipidaemia, unbalanced diabetes mellitus (glycated haemoglobin ≥7.5%), duration of diabetes >5 years, hepatic steatosis and the co-existence of various heart diseases. To conclude, all these risk factors aforementioned can decrease the effectiveness of treatment and can have a significant impact on the quality of life, if they are not well known.

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Epidemiology and Economic Impact of Foot Ulcers

Cited by 6 publications

References 84 publications

The efficacy of electroacupuncture in among early diabetic patients with lower limb arteriosclerotic wounds

The efficacy of electroacupuncture in among early diabetic patients with lower limb arteriosclerotic wounds

Dual-modal photoacoustic and ultrasound imaging: from preclinical to clinical applications

Risk assessment of amputation in patients with diabetic foot

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